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2-Methoxyaniline hydrochloride

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Identification
Molecular formula
C7H9NO · HCl
CAS number
637-58-1
IUPAC name
2-methoxyaniline;hydrochloride
State
State
At room temperature, 2-Methoxyaniline hydrochloride is in a solid state. It is stable under normal conditions but should be stored in a dry environment to prevent clumping or degradation.
Melting point (Celsius)
133.00
Melting point (Kelvin)
406.15
Boiling point (Celsius)
252.00
Boiling point (Kelvin)
525.15
General information
Molecular weight
157.61g/mol
Molar mass
157.6100g/mol
Density
1.2400g/cm3
Appearence

2-Methoxyaniline hydrochloride appears as a white to off-white crystalline solid. It is often sold as a powder or in a crystalline form, and it is hygroscopic, meaning it can absorb moisture from the air.

Comment on solubility

Solubility of 2-Methoxyaniline Hydrochloride

2-Methoxyaniline hydrochloride, a compound derived from methoxyaniline, exhibits interesting solubility characteristics, primarily influenced by its ionic nature owing to the presence of the hydrochloride salt form. When considering its solubility properties, several key aspects emerge:

  • Solvent Compatibility: This compound is typically soluble in water due to its ionic structure, which allows it to interact favorably with polar solvents.
  • Solubility in Organic Solvents: 2-Methoxyaniline hydrochloride shows varying solubility in organic solvents, being more soluble in ethanol and methanol, while generally having lower solubility in non-polar solvents.
  • Temperature Dependence: Solubility can be affected by temperature; typically, an increase in temperature leads to greater solubility in both polar and non-polar solvents.
  • pH Influence: As an amine salt, its solubility is also influenced by the pH of the solution, with higher solubility observed in acidic environments.

To summarize, 2-methoxyaniline hydrochloride is a compound with good solubility in polar solvents, especially water and alcohols, highlighting its practical utility in various chemical applications. Its ability to dissolve well in these solvents makes it a versatile compound for laboratory use.

Interesting facts

Interesting Facts About 2-Methoxyaniline Hydrochloride

2-Methoxyaniline hydrochloride, also known as o-Methoxyaniline hydrochloride, is a fascinating chemical compound with a variety of applications and properties that intrigue scientists and students alike.

Key Applications

  • Organic Synthesis: This compound serves as a versatile building block in organic synthesis, contributing to the development of various pharmaceuticals and dyes.
  • Intermediate in Dye Chemistry: It is utilized in the synthesis of azo dyes, which play a crucial role in textile coloring.
  • Analytical Chemistry: 2-Methoxyaniline hydrochloride is used as a reagent in various analytical methods, helping to identify different chemical substances.

Properties and Characteristics

Like many amines, 2-methoxyaniline exhibits interesting properties due to the presence of both the amine and methoxy functional groups. These groups contribute to its reactivity and the ability to undergo various chemical transformations.

Safety Considerations

As with many organic compounds, it is essential to handle 2-methoxyaniline hydrochloride with care. Some notable safety considerations include:

  • Toxicity: It is important to be aware of its potential toxic effects and handle it in a well-ventilated area.
  • Protective Equipment: Use appropriate protective gear such as gloves and goggles when preparing or using this compound.

Fun Fact

Did you know that the methoxy group (-OCH3) not only alters the reactivity of the aniline group but also enhances its solubility in organic solvents? This property makes 2-methoxyaniline hydrochloride a valuable compound in various chemical processes.

In conclusion, 2-methoxyaniline hydrochloride stands out due to its diverse applications in organic synthesis and analytical methods while also presenting certain health and safety considerations. This compound truly reflects the intricacy and beauty of organic chemistry.

Synonyms
O-ANISIDINE HYDROCHLORIDE
134-29-2
2-Methoxyaniline hydrochloride
O-Anisidine HCl
o-Anisidine.HCl
2-Methoxyaniline HCl
Fast Red BB Base
o-Anisidine, hydrochloride
Benzenamine, 2-methoxy-, hydrochloride
CCRIS 46
o-Methoxyaniline hydrochloride
2-Methoxybenzenamine hydrochloride
DTXSID8020092
C.I. 37115
MFCD00054334
Anisidine hydrochloride, o-
74SDU6V9SC
DTXCID3092
2-methoxyaniline;hydrochloride
2-Anisidine hydrochloride
2-Aminoanisole hydrochloride
o-Anisylamine hydrochloride
o-Aminoanisole hydrochloride
CAS-134-29-2
o-Methoxyphenylamine hydrochloride
NCI-C03747
2-Methoxybenzeneamine hydrochloride
2-Methoxy-1-aminobenzene hydrochloride
UNII-74SDU6V9SC
SCHEMBL892262
CHEMBL3183318
AAA13429
Tox21_201358
Tox21_302807
MFCD28397267
AKOS024272193
NCGC00256514-01
NCGC00258910-01
AS-11121
SY057256
SY277586
DB-240235
A0489
CS-0150305
Benzenamine, 2-methoxy-, hydrochloride (1:1)
D88267
EN300-1265941
F8881-5656