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2-Methoxybenzoic acid

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Identification
Molecular formula
C8H8O3
CAS number
579-75-9
IUPAC name
2-methoxybenzoic acid
State
State

At room temperature, 2-Methoxybenzoic acid is in a solid state. It is less soluble in water but can be soluble in organic solvents like ethanol. Its solid-state makes it handy for various chemical, pharmaceutical applications, and as an intermediate in organic synthesis.

Melting point (Celsius)
105.00
Melting point (Kelvin)
378.00
Boiling point (Celsius)
285.00
Boiling point (Kelvin)
558.00
General information
Molecular weight
152.15g/mol
Molar mass
152.1470g/mol
Density
1.2390g/cm3
Appearence

2-Methoxybenzoic acid, also known as o-anisic acid, typically appears as a white crystalline solid or powder. It can sometimes display a slightly off-white color, depending on the purity and presence of impurities. The crystals are often needle-like or prismatic in structure, offering a sparkling appearance in light.

Comment on solubility

Solubility of 2-methoxybenzoic acid

2-methoxybenzoic acid, with the chemical formula C9H10O3, exhibits fascinating solubility characteristics influenced by its molecular structure. The presence of both a methoxy group and a carboxylic acid group greatly affects its solubility in various solvents.

Key Points of Solubility:

  • Polar Solvents: 2-methoxybenzoic acid is relatively soluble in polar solvents such as water and alcohols due to hydrogen bonding capabilities with the carboxylic acid group.
  • Nonpolar Solvents: The compound shows limited solubility in nonpolar solvents like hexane, which can be attributed to the polar nature of its functional groups.
  • Temperature Dependence: Solubility may also enhance with increasing temperature, resulting in better dissolution in solvents.
  • pH Influence: In aqueous solutions, the solubility of 2-methoxybenzoic acid can vary with pH, as the ionization of its carboxylic group can lead to increased solubility in alkaline conditions.

In summary, the solubility of 2-methoxybenzoic acid can be best described as moderate in polar solvents and limited in nonpolar environments. Understanding these properties is crucial for applications in areas such as pharmaceuticals and chemical synthesis, where solvent choice plays a vital role in achieving desired outcomes.

Interesting facts

Interesting Facts about 2-Methoxybenzoic Acid

2-Methoxybenzoic acid, also known as o-methoxybenzoic acid, is an intriguing compound that holds significance in various fields of chemistry and applications. Here are some key highlights:

  • Structural Insights: This compound is characterized by a methoxy group (-OCH3) attached to the ortho position of the benzoic acid structure. This positioning significantly influences its chemical properties and reactivity.
  • Natural Occurrence: Interestingly, 2-methoxybenzoic acid has been isolated from various natural sources including certain *plants and fungi*. Its presence in nature suggests potential roles in metabolic processes or ecological interactions.
  • Synthetic Utility: The compound serves as an essential intermediate in organic synthesis. Its versatile structure allows for modifications that lead to the production of various pharmaceuticals and agrochemicals.
  • Therapeutic Potential: Research has indicated that derivatives of 2-methoxybenzoic acid may exhibit *anti-inflammatory* and *antioxidant* properties, making it a compound of interest in medicinal chemistry.
  • Unique Reactions: It can undergo multiple types of chemical reactions, including esterification and amidation, which can lead to the formation of a wide array of compounds with distinct functionalities.

In conclusion, 2-methoxybenzoic acid's unique structure, occurrence in nature, and synthetic utility make it a fascinating subject of study in organic chemistry. As stated by chemists, “Understanding compounds like this one unveils pathways to innovative solutions in medicine and agriculture.”

Synonyms
2-METHOXYBENZOIC ACID
o-Anisic acid
O-Methylsalicylic acid
o-Methoxybenzoic acid
Benzoic acid, 2-methoxy-
Salicylic acid methyl ether
O-Methoxy benzoic acid
CHEBI:421840
UNII-49WA6Z7GZA
EINECS 209-447-8
49WA6Z7GZA
BRN 0509929
AI3-20226
O-Anisic acid, 8CI
NSC-3778
METHOXYBENZOIC ACID, O-
DTXSID3060376
FEMA NO. 3943
FEMA 3943
4-10-00-00130 (Beilstein Handbook Reference)
2-METHOXYBENZOIC ACID [FHFI]
o-anisate
oAnisic acid
o-methoxybenzoate
2Anisic acid
2-Anisate
2-methoxy-benzoate
oMethoxybenzoic acid
ortho-methoxybenzoate
OMethylsalicylic acid
Salicylate methyl ether
Benzoic acid, 2methoxy
Kyselina 2methoxybenzoova
DTXCID6042282
ilujqpxnxacgan-uhfffaoysa-n
inchi=1/c8h8o3/c1-11-7-5-3-2-4-6(7)8(9)10/h2-5h,1h3,(h,9,10
579-75-9
2-Anisic acid
529-75-9
2-Methoxy-benzoic acid
2-Methoxybenzoicacid
MFCD00002431
Kyselina 2-methoxybenzoova
NSC 3778
ortho-methoxybenzoic acid
BENZOIC ACID,2-METHOXY
Kyselina 2-methoxybenzoova [Czech]
71F
o-Anisic Acid; 2-Methoxybenzoic Acid; NSC 3778; O-Methylsalicylic Acid; Salicylic Acid Methyl Ether; o-Methoxybenzoic Acid
methyl salicylic acid
anisole carboxylic acid
2-methoxy benzoic acid
Epitope ID:124944
1-carboxy-2-methoxybenzene
o-Anisic acid, >=99%
SCHEMBL3527
TimTec1_004173
CHEMBL192311
NSC3778
HMS1545N15
HY-N1393
AB2883
BBL036896
s6295
STL168881
AKOS000103118
AC-3023
CS-W019888
FM00504
PS-5405
o-Anisic acid;Salicylic acid methyl ether
SY003594
DB-014137
DB-030864
A0481
A1729
NS00015109
2-Methoxybenzoic acid, ReagentPlus(R), 99%
EN300-18034
AQ-344/40173719
Q2018545
2-Methoxybenzoic acid, Vetec(TM) reagent grade, 98%
Z57127524
F9995-1670