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Methyl salicylate

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Identification
Molecular formula
C8H8O3
CAS number
119-36-8
IUPAC name
2-methoxycarbonylbenzoic acid
State
State

At room temperature, methyl salicylate is in a liquid state. Its clear to pale yellow appearance and distinct aroma contribute to its common use in topical analgesics and as a flavoring agent.

Melting point (Celsius)
-9.00
Melting point (Kelvin)
264.15
Boiling point (Celsius)
222.00
Boiling point (Kelvin)
495.15
General information
Molecular weight
152.15g/mol
Molar mass
152.1490g/mol
Density
1.1740g/cm3
Appearence

Methyl salicylate is a colorless or pale yellow liquid with an aroma of wintergreen. It is often recognized for its sweet, fruity scent and is used in various applications for its fragrance and flavor.

Comment on solubility

Solubility of 2-methoxycarbonylbenzoic acid

2-methoxycarbonylbenzoic acid, with its unique structure, presents interesting solubility characteristics that can be influenced by several factors. Its solubility profile is notable for the following reasons:

  • Polarity: The presence of both the carboxylic acid group and the methoxycarbonyl group enhances its polarity, making it soluble in polar solvents.
  • Solvent Interaction: It typically exhibits good solubility in water due to hydrogen bonding capabilities, but its solubility can vary considerably in non-polar solvents.
  • Temperature Dependency: Like many organic acids, the solubility of 2-methoxycarbonylbenzoic acid tends to increase with higher temperatures, making heat a critical factor for its dissolution.
  • pH Influence: The pH of the solution can significantly impact solubility, as the deprotonation of the carboxylic acid group under alkaline conditions enhances its solubility in water.

In brief, while 2-methoxycarbonylbenzoic acid is generally soluble in polar solvents, particularly under certain conditions, its solubility is affected by factors such as temperature, solvent choice, and solution pH. Understanding these aspects is key in applications where solubility plays a vital role.

Interesting facts

Interesting Facts about 2-Methoxycarbonylbenzoic Acid

2-Methoxycarbonylbenzoic acid, also known by its common name, is a fascinating compound with diverse applications in both chemical synthesis and pharmaceuticals. This compound is particularly interesting due to its unique structure and reactivity, making it a valuable intermediate in organic chemistry.

Key Characteristics:

  • Functional Diversity: The presence of both carboxylic acid and ester functional groups allows for a variety of chemical reactions, including esterification and amidation.
  • Biological Relevance: Compounds related to 2-methoxycarbonylbenzoic acid often exhibit biological activity, leading to its potential use in medicinal chemistry for developing new drugs.
  • Solvent Use: This compound can also be employed as a solvent or reagent in organic synthesis, thus facilitating multiple reactions in laboratory settings.

Applications:

  • Synthesis: It is widely used as a precursor in the synthesis of various organic compounds, particularly in creating more complex structures.
  • Pharmaceutical Industry: The reactivity of 2-methoxycarbonylbenzoic acid makes it a candidate for developing pharmaceuticals that target specific biological pathways.

The structure of 2-methoxycarbonylbenzoic acid lends itself to numerous applications and research avenues. As with many carboxylic acids, *exploring its reactivity* has broad implications in synthetic and medicinal chemistry. Scientists frequently investigate its derivatives for enhanced properties or effects, following the motto, "Innovation lies in variation."

In conclusion, 2-methoxycarbonylbenzoic acid serves as a prime example of how a single compound can bridge the gap between fundamental chemistry and practical applications in science.

Synonyms
2-(Methoxycarbonyl)benzoic acid
4376-18-5
MONOMETHYL PHTHALATE
Methyl hydrogen phthalate
o-(Methoxycarbonyl)benzoic acid
Phthalic acid, monomethyl ester
1,2-Benzenedicarboxylic acid, monomethyl ester
D 3 (ester)
Monomethyl 1,2-benzenedicarboxylate
NSC 8281
Methyl 2-Carboxybenzoate
Phthalic acid, methyl ester
2STT6D18JR
DTXSID9040001
2-(1-Methoxycarbonyl)benzoic Acid
NSC-8281
EINECS 224-476-6
O-(methoxycarbonyl)benzoate
2-(Methoxycarbonyl)benzoate
AI3-02332
DTXCID7020001
1,2-benzenedicarboxylic acid monomethyl ester
1,2-benzenedicarboxylic acid, 1-methyl ester
Monomethyl phthalic acid
Phthalic acid, monomethyl ester (8CI)
1,2-Benzenedicarboxylic acid, monomethyl ester (9CI)
224-476-6
inchi=1/c9h8o4/c1-13-9(12)7-5-3-2-4-6(7)8(10)11/h2-5h,1h3,(h,10,11
mono-Methyl phthalate
2-methoxycarbonylbenzoic acid
MFCD00002466
CHEBI:89749
Phthalic acid, mono-methyl ester
D 3
Phthalic acid monomethyl ester
Methyl phthalate (VAN)
UNII-2STT6D18JR
D 3 (VAN)
METHYLPHTHALATE
2-carbomethoxybenzoic acid
BIDD:PXR0156
SCHEMBL40534
mono-Methyl phthalate, 97%
2-(Methoxycarbonyl)benzoicacid
CHEMBL243609
Monomethyl phthalate (Standard)
HY-Y1097R
NSC8281
2-(Methoxycarbonyl)benzoic acid #
ALBB-024862
CS-D1453
HY-Y1097
Tox21_300735
STK387125
AKOS000278869
FM26065
NCGC00164438-01
NCGC00164438-02
NCGC00164438-03
NCGC00164438-04
NCGC00254641-01
BP-13059
mono-Methyl phthalate, analytical standard
SY010760
TS-02513
CAS-4376-18-5
DB-027127
NS00015621
EN300-67468
AB01334586-02
AR-360/13197749
Q26840745
F1791-1742
Z1080376828
1,2-Benzenedicarboxylic acid 1-methyl ester;Phthalic acid methyl ester;Phthalic acid monomethyl ester
R3O