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2-Methoxydibenzofuran-3-amine

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Identification
Molecular formula
C13H11NO2
CAS number
.
IUPAC name
2-methoxydibenzofuran-3-amine
State
State

At room temperature, 2-Methoxydibenzofuran-3-amine is a solid. It is not hygroscopic and remains stable under normal laboratory conditions. Appropriate storage is in a sealed container to limit exposure to moisture and air.

Melting point (Celsius)
233.00
Melting point (Kelvin)
506.15
Boiling point (Celsius)
380.00
Boiling point (Kelvin)
653.15
General information
Molecular weight
223.26g/mol
Molar mass
223.2560g/mol
Density
1.3480g/cm3
Appearence

2-Methoxydibenzofuran-3-amine usually appears as a crystalline solid. The crystals may vary in color ranging from white to pale yellow, depending on purity and conditions of observation. The compound can be manipulated as a powder or in larger crystalline form and it usually projects a distinct aromatic odor characteristic of dibenzofuran derivatives.

Comment on solubility

Solubility of 2-methoxydibenzofuran-3-amine

When considering the solubility of 2-methoxydibenzofuran-3-amine, several factors come into play that can significantly affect its dissolving capabilities. This compound exhibits moderate solubility in various solvents, typically influenced by its molecular structure:

  • Polarity: The presence of the methoxy group (-OCH3) contributes to the compound's polar character, enhancing its solubility in polar solvents like methanol and ethanol.
  • Hydrogen bonding: 2-methoxydibenzofuran-3-amine can engage in hydrogen bonding, which may facilitate dissolution in both polar and some less polar solvents.
  • Aromatic interactions: The aromatic rings present in the structure allow for π-π interactions, particularly in non-polar organic solvents like toluene or hexane. However, the extent of solubility may be limited.

In general, it is valuable to recognize the solubility trend:

  1. In polar solvents: Increased solubility due to favorable interactions.
  2. In non-polar solvents: Limited solubility, relying on π-π interactions and minimal polar character.
  3. Temperature effects: As with many compounds, solubility may improve with elevation in temperature, allowing more molecules to disperse in the solvent.

To summarize, the solubility of 2-methoxydibenzofuran-3-amine can be characterized as:

  • Moderate in polar solvents.
  • Limited in non-polar solvents.
  • Responsive to temperature changes.

Understanding these solubility properties is crucial for practical applications in research and industry, particularly in fields such as pharmaceuticals and material science.

Interesting facts

Interesting Facts about 2-Methoxydibenzofuran-3-amine

2-Methoxydibenzofuran-3-amine is a fascinating organic compound that has garnered interest in various areas of chemical research. Here are some intriguing aspects of this compound:

  • Structure and Functionality: The molecular architecture of 2-methoxydibenzofuran-3-amine features a dibenzofuran moiety, which is characterized by its fused aromatic rings. This unique structure not only enhances the stability of the compound but also its potential reactivity.
  • Biological Significance: Compounds like 2-methoxydibenzofuran-3-amine are often investigated for their pharmacological properties. Studies have suggested that this compound may interact with various biological targets, making it a candidate for drug development.
  • Research Applications: The compound may be utilized in various fields, such as medicinal chemistry, materials science, and organic synthesis. Its diverse applications stem from its ability to act as a versatile building block in the creation of more complex molecules.
  • Chemical Synthesis: Synthesis of 2-methoxydibenzofuran-3-amine can be achieved through a series of well-known organic reactions, highlighting the ingenuity and efficiency of modern synthetic techniques in organic chemistry.
  • Safety and Handling: As with many organic compounds, proper safety precautions should be taken when working with 2-methoxydibenzofuran-3-amine to minimize health risks and ensure a safe laboratory environment.

As a student or scientist, exploring compounds like 2-methoxydibenzofuran-3-amine opens doors to understanding complex interactions in both chemistry and biological systems. The study of such compounds not only enhances our foundational knowledge but inspires innovation in various scientific fields.

Synonyms
3-Amino-2-methoxydibenzofuran
5834-17-3
2-Methoxy-3-aminodibenzofuran
2-Methoxy-3-dibenzofuranamine
2-Amino-3-methoxydiphenylenoxyd
3-DIBENZOFURANAMINE, 2-METHOXY-
BRN 0176944
36C8S7H3NZ
2-Amino-3-methoxydiphenylenoxyd [German]
DTXSID9020825
DTXCID70825
4-18-00-07352 (Beilstein Handbook Reference)
METHOXY-3-AMINODIBENZOFURAN, 2-
611-644-2
2-Methoxydibenzo[b,d]furan-3-amine
(2-methoxydibenzo[b,d]furan-3-yl)amine
2-methoxydibenzofuran-3-amine
3-Amino-2-methoxydibenzo[b,d]furan
EN300-20521
UNII-36C8S7H3NZ
3-Amino-2-methoxy-dibenzofuran
MFCD00011554
2-(methyloxy)dibenzo[b,d]furan-3-amine
Oprea1_315231
SCHEMBL92042
CHEMBL3188571
BDBM626089
ALBB-024998
STR05048
Tox21_200262
BBL027784
STK400206
3-Amino-2-methoxydibenzofuran, 97%
AKOS000119461
2-Methoxydibenzo[b,d]furan-3-amine #
CCG-274808
FA02148
NCGC00248582-01
NCGC00257816-01
CAS-5834-17-3
CS-0204352
NS00033908
E85366
AG-690/11961982
SR-01000107582
SR-01000107582-1
Q27256551
F0919-0335
Z104478554
4-methoxy-8-oxatricyclo[7.4.0.0,2,7]trideca-1(9),2(7),3,5,10,12-hexaen-5-amine
4-METHOXY-8-OXATRICYCLO[7.4.0.0(2),?]TRIDECA-1(9),2(7),3,5,10,12-HEXAEN-5-AMINE
InChI=1/C13H11NO2/c1-15-13-6-9-8-4-2-3-5-11(8)16-12(9)7-10(13)14/h2-7H,14H2,1H