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2-(Methoxymethyl)-5-nitrofuran

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Identification
Molecular formula
C6H7NO4
CAS number
13728-47-9
IUPAC name
2-(methoxymethyl)-5-nitro-furan
State
State

At room temperature, 2-(methoxymethyl)-5-nitrofuran is typically in a solid state.

Melting point (Celsius)
45.00
Melting point (Kelvin)
318.15
Boiling point (Celsius)
313.00
Boiling point (Kelvin)
586.15
General information
Molecular weight
171.13g/mol
Molar mass
171.1410g/mol
Density
1.2758g/cm3
Appearence

2-(Methoxymethyl)-5-nitrofuran appears as a yellow crystalline solid.

Comment on solubility

Solubility of 2-(methoxymethyl)-5-nitro-furan

When examining the solubility of 2-(methoxymethyl)-5-nitro-furan, it is crucial to consider several factors that influence its dissolution in various solvents. This compound exhibits moderate solubility in polar organic solvents such as methanol and ethanol due to the presence of the methoxymethyl group, which enhances its interaction with these solvents.

However, its solubility in water is relatively low. This can be attributed to:

  • The hydrophobic nature of the furan ring
  • The electronegative nitro group, which may deter solvation by water molecules

Conversely, 2-(methoxymethyl)-5-nitro-furan is likely to be more soluble in:

  • Dimethyl sulfoxide (DMSO)
  • Acetonitrile

As a general guideline, the solubility of this compound can be summarized as:

  • Good: Methanol, Ethanol
  • Poor: Water
  • Moderate to Good: DMSO, Acetonitrile

Overall, the solubility characteristics of 2-(methoxymethyl)-5-nitro-furan underline the importance of selecting the right solvent for its application in chemical processes.

Interesting facts

Exploring 2-(methoxymethyl)-5-nitro-furan

The compound 2-(methoxymethyl)-5-nitro-furan is a fascinating member of the furan family, recognized for its intriguing chemical properties and potential applications in various fields. Here are some interesting facts about this compound:

  • Versatile Structure: The presence of a methoxymethyl group and a nitro substituent on the furan ring enhances its chemical reactivity, making it a subject of interest in synthetic organic chemistry.
  • Potential Applications: Compounds like 2-(methoxymethyl)-5-nitro-furan are investigated for their role in pharmaceuticals, particularly as intermediates in the synthesis of biologically active molecules.
  • Remarkable Reactivity: The nitro group on the furan ring can undergo various chemical transformations, such as nitration and reduction, leading to the formation of new compounds that could exhibit distinct biological properties.
  • Environmental Impact: The study of furan derivatives, including this compound, is paramount in environmental chemistry due to their potential impact as pollutants and their behavior in biological systems.
  • Historical Context: The exploration of nitro compounds has roots dating back to the late 19th century, marking major advancements in both scientific understanding and practical applications in fields such as agriculture and medicine.

As a student or scientist diving into the world of chemical compounds, the study of 2-(methoxymethyl)-5-nitro-furan invites one to appreciate the delicate balance between structure and reactivity in organic chemistry. The compound not only embodies essential chemical principles but also serves as a stepping stone for future innovations.

Synonyms
2-(METHOXYMETHYL)-5-NITROFURAN
Furaspor
Furamicid
Furbenal
5-Nitro-2-furfuryl methyl ether
Furan, 2-(methoxymethyl)-5-nitro-
N4EAX2HUWL
UNII-N4EAX2HUWL
NSC-1196
EINECS 209-586-4
NSC-404090
AI3-17341
DTXSID9041996
NITROFURFURYL METHYL ETHER
NF-45
NSC 1196
NSC 404090
2-(METHOXYMETHYL)-5-NITROFURAN [MI]
DTXCID7021996
209-586-4
586-84-5
NMFE
NF 45
SCHEMBL436038
CHEBI:34458
NSC1196
JXUMCVDPMJWGSI-UHFFFAOYSA-N
NSC404090
methyl (5-nitro-2-furyl)methyl ether
NS00033997
Q27116083