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Methamphetamine

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Identification
Molecular formula
C10H15N
CAS number
51-57-0
IUPAC name
2-methyl-1-phenyl-propan-2-amine
State
State

Methamphetamine is generally found in a crystalline solid state under room temperature conditions. It can be dissolved in a liquid solution for various forms of usage. The crystalline form is typically clear or slightly off-white.

Melting point (Celsius)
170.00
Melting point (Kelvin)
443.15
Boiling point (Celsius)
212.00
Boiling point (Kelvin)
485.15
General information
Molecular weight
149.23g/mol
Molar mass
149.2330g/mol
Density
0.9378g/cm3
Appearence

Methamphetamine typically appears as a white, odorless, crystalline powder in its pure form. It is often sold as a crystalline solid or as bright white shards resembling glass fragments or ice, hence the street name "crystal meth". The solution form of the compound is clear or colored depending on the impurities contained within.

Comment on solubility

Solubility of 2-methyl-1-phenyl-propan-2-amine (C10H15N)

The solubility of 2-methyl-1-phenyl-propan-2-amine presents an interesting profile due to its chemical structure. This compound, often classified as a secondary amine, exhibits limited solubility in water, primarily due to the hydrophobic characteristics imparted by its alkyl and phenyl groups. However, it can demonstrate enhanced solubility in organic solvents. Here are some key points regarding its solubility:

  • Solubility in Water: Generally low, owing to the bulky non-polar groups.
  • Solubility in Organic Solvents: Highly soluble in non-polar and mildly polar solvents, such as ethanol and acetone.
  • Influence of Temperature: Increased temperatures often enhance solubility in organic solvents.
  • pH Dependence: The presence of amine functional groups can alter solubility in various pH conditions, often leading to improved solubility in acidic environments.

In summary, while 2-methyl-1-phenyl-propan-2-amine might struggle to dissolve in polar solvents like water, it finds a more accommodating environment in non-polar or mildly polar organic solvents. As the saying goes, "like dissolves like," which aptly applies to this compound's solubility behavior.

Interesting facts

Exploring 2-methyl-1-phenyl-propan-2-amine

2-methyl-1-phenyl-propan-2-amine, commonly known in the scientific community for its role as a stimulant and psychoactive compound, has captured interest due to its unique chemical structure and properties. Here are some compelling facts about this compound:

  • Structural Significance: The presence of both a methyl group and a phenyl group makes this compound a notable example in organic chemistry, showcasing how substituents can significantly alter biochemical properties.
  • Psychoactive Effects: This compound is often associated with the central nervous system's stimulant effects, which can lead to increased alertness and energy levels, making it of interest in both medical and recreational contexts.
  • Medicinal Research: Compounds like 2-methyl-1-phenyl-propan-2-amine are studied for their potential in treating certain disorders, such as Attention Deficit Hyperactivity Disorder (ADHD) and narcolepsy, due to their ability to enhance focus and reduce fatigue.
  • Synthetic Pathways: The synthesis of 2-methyl-1-phenyl-propan-2-amine can involve various routes, including alkylation and amination processes, highlighting key techniques in organic synthesis chemistry.
  • Legal Status: The legal status of this compound can vary by region and its classification as a controlled substance in many areas reflects its potential for abuse and dependency.

Overall, 2-methyl-1-phenyl-propan-2-amine serves as an important case study within organic chemistry and pharmacology, illustrating the delicate balance between therapeutic benefits and risks associated with psychoactive substances. As research continues, the implications of this compound in real-world applications will likely evolve.

Synonyms
phentermine
122-09-8
2-methyl-1-phenylpropan-2-amine
Normephentermine
Duromine
Fentermina
Lipopill
Mirapront
Lonamin
Omnibex
Linyl
1,1-Dimethyl-2-phenylethylamine
alpha,alpha-Dimethylphenethylamine
Ionamin
Phenterminum
Obermine
Phentrol
Phentrol 2
Phentrol 3
Phentrol 4
2-Phenyl-tert-butylamine
Phenyl-tert-butylamine
Adipex-P
alpha-Benzylisopropylamine
Phenyl-tertiary-butylamine
Fentermina [INN-Spanish]
Phenterminum [INN-Latin]
RCRA waste number P046
2-Amino-2-methyl-1-phenylpropane
alpha,alpha-Dimethylbenzeneethanamine
Benzeneethanamine, alpha,alpha-dimethyl-
HSDB 3158
alpha,alpha-Dimethyl-beta-phenylethylamine
Phentermine resin
UNII-C045TQL4WP
EINECS 204-522-1
C045TQL4WP
Ethanamine, 1,1-dimethyl-2-phenyl-
NSC-759163
BRN 0970319
CHEBI:8080
Phenethylamine, alpha,alpha-dimethyl-
CHEMBL1574
DTXSID9023461
Benzeneethanamine, .alpha.,.alpha.-dimethyl-
EC 204-522-1
Phentermine-d5
QSYMIA COMPONENT PHENTERMINE
NSC 759163
DEA No. 1640
1,1-DIMETHYL-2-PHENYL-ETHYLAMINE
Fentermina (INN-Spanish)
Phenterminum (INN-Latin)
PHENTERMINE (MART.)
PHENTERMINE [MART.]
Phentermine [USAN:INN:BAN]
Phentermine (1 mg/ml in Methanol)
Phentermine (1.0mg/mL in Methanol)
SR-05000001805
(alpha,alpha)-Dimethylphenethylamine
MG 18570
Phentermine (USAN/INN)
RCRA waste no. P046
Phentermine ResinER
.alpha.,.alpha.-Dimethylphenethylamine
1246819-25-9
PHENTERMINE [MI]
PHENTERMINE [INN]
1-benzyl-iso-propyl amine
PHENTERMINE [HSDB]
PHENTERMINE [USAN]
PHENTERMINE [VANDF]
SCHEMBL26615
PHENTERMINE [WHO-DD]
DTXCID303461
GTPL7269
122-09-8 (free base)
A08AA01
HMS2093B16
Pharmakon1600-01505660
Phentermine 0.1 mg/ml in Methanol
Phentermine 1.0 mg/ml in Methanol
.alpha..alpha.Dimethylphenethylamine
BDBM50246598
NSC759163
AKOS004123261
PHENTERMINE COMPONENT OF QSYMIA
AB02355
DB00191
NCGC00263911-02
Phenethylamine, .alpha.,.alpha.-dimethyl-
SBI-0206817.P001
D1291
NS00008990
C07438
D05458
Q418157
SR-05000001805-1
SR-05000001805-2
BRD-K96319534-001-01-7
BRD-K96319534-003-03-9
InChI=1/C10H15N/c1-10(2,11)8-9-6-4-3-5-7-9/h3-7H,8,11H2,1-2H
204-522-1