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N-phenyl-2-methyl-1,3-dioxoisoquinoline-4-carboxamide

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Identification
Molecular formula
C17H12N2O4
CAS number
51638-09-8
IUPAC name
2-methyl-1,3-dioxo-N-phenyl-4H-isoquinoline-4-carboxamide
State
State

At room temperature, N-phenyl-2-methyl-1,3-dioxoisoquinoline-4-carboxamide is in a solid state, commonly in crystalline form.

Melting point (Celsius)
230.00
Melting point (Kelvin)
503.15
Boiling point (Celsius)
346.30
Boiling point (Kelvin)
619.45
General information
Molecular weight
278.28g/mol
Molar mass
278.2760g/mol
Density
1.3200g/cm3
Appearence

This compound typically appears as a crystalline solid with a white to off-white color. It may form as needles or powder.

Comment on solubility

Solubility of 2-methyl-1,3-dioxo-N-phenyl-4H-isoquinoline-4-carboxamide

The solubility of 2-methyl-1,3-dioxo-N-phenyl-4H-isoquinoline-4-carboxamide can be quite complex, influenced by various factors including polarity, molecular structure, and the presence of specific functional groups. Understanding its solubility properties is essential for applications in pharmaceuticals and chemical synthesis.

Factors Affecting Solubility

  • Polarity: The presence of polar functional groups typically increases solubility in polar solvents, while non-polar regions favor solubility in organic solvents.
  • Molecular Structure: The rigid structure of isoquinoline derivatives may hinder solubility in water.
  • Hydrogen Bonding: The ability to form hydrogen bonds can enhance solubility in specific solvents.

As a result, while this compound may exhibit limited solubility in water, it is likely to be more soluble in organic solvents such as dimethyl sulfoxide (DMSO) or ethanol. It is noteworthy to consider:

  1. Consulting relevant solubility data can provide insight into expected behavior.
  2. Conducting experiments in various solvents can yield a practical understanding of its solubility.

In conclusion, comprehending the solubility of 2-methyl-1,3-dioxo-N-phenyl-4H-isoquinoline-4-carboxamide is fundamental for its utilization in research and industrial applications, necessitating careful consideration of solvent choice.

Interesting facts

Interesting Facts about 2-methyl-1,3-dioxo-N-phenyl-4H-isoquinoline-4-carboxamide

The compound 2-methyl-1,3-dioxo-N-phenyl-4H-isoquinoline-4-carboxamide is a fascinating example of how complex organic molecules can be synthesized and utilized in various fields of chemistry. Here are some intriguing aspects of this compound:

  • Structural Complexity: This compound features a unique isoquinoline structure, which is known for its diverse biological activities. Its combination of a dioxo group and the phenyl moiety increases its versatility.
  • Applications: Compounds of this nature are often explored for their potential as pharmaceuticals. Research has shown that isoquinoline derivatives can exhibit anti-inflammatory, antimicrobial, and anticancer properties, making them of great interest in medicinal chemistry.
  • Research Significance: Studies involving isoquinoline derivatives contribute to the development of new drugs. There is ongoing research aimed at understanding how modifications in the molecular structure can enhance biological efficacy while reducing side effects.
  • Synthesis Techniques: The synthesis of such compounds often employs methods like condensation reactions and cyclization strategies. These techniques showcase the creativity and precision required in modern organic synthesis.
  • Analytical Interest: The characterization of this compound can be effectively conducted using techniques like NMR (Nuclear Magnetic Resonance) and IR (Infrared Spectroscopy), which allow scientists to confirm the structural integrity and functional groups present.

Overall, the exploration of 2-methyl-1,3-dioxo-N-phenyl-4H-isoquinoline-4-carboxamide not only enhances our understanding of organic compounds but also opens new avenues for innovation in drug development and materials science.

Synonyms
YI7IFA9P4W
1,2,3,4-TETRAHYDRO-2-METHYL-1,3-DIOXO-4-ISOQUINOLINE CARBOXANILIDE
21389-75-3
1,2,3,4-Tetrahydro-2-methyl-1,3-dioxo-N-phenyl-4-isoquinolinecarboxamide
4-Isoquinolinecarboxamide, 1,2,3,4-tetrahydro-2-methyl-1,3-dioxo-N-phenyl-
UNII-YI7IFA9P4W
SCHEMBL8280317
BDBM50057006
3-Hydroxy-2-methyl-1-oxo-1,2-dihydro-isoquinoline-4-carboxylic acid phenylamide