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2-methylindole

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Identification
Molecular formula
C9H9N
CAS number
95-20-5
IUPAC name
2-methyl-1H-indole;5-methyl-1H-indole
State
State
Solid at room temperature.
Melting point (Celsius)
58.00
Melting point (Kelvin)
331.15
Boiling point (Celsius)
251.00
Boiling point (Kelvin)
524.15
General information
Molecular weight
131.18g/mol
Molar mass
131.1780g/mol
Density
1.0617g/cm3
Appearence

2-Methylindole appears as a yellow to off-white solid with a distinctive odor. It may occur in crystalline or powder form.

Comment on solubility

Solubility of 2-methyl-1H-indole and 5-methyl-1H-indole

The solubility of 2-methyl-1H-indole and 5-methyl-1H-indole in various solvents can greatly influence their applications in chemical research and industry. Both of these compounds belong to the indole family, which is recognized for their unique molecular structure and properties.

Key Points on Solubility:

  • Non-polar Solvents: These compounds demonstrate higher solubility in non-polar solvents such as hexane or toluene, which is attributed to their hydrophobic nature.
  • Polar Solvents: In contrast, their solubility in polar solvents like water is quite limited, which can be a significant barrier for certain applications that require aqueous solutions.
  • Temperature Dependency: Solubility can often increase with temperature; therefore, adjustments in conditions can make them more soluble in some solvents under specific circumstances.

As stated, "The solubility of a compound is one of the most critical parameters in determining its functionality and applicability." Thus, understanding the solubility profile of 2-methyl-1H-indole and 5-methyl-1H-indole can help chemists design more effective experiments and applications.

In summary, these compounds are better suited for use in non-polar environments, and researchers may need to explore innovative methods to utilize them effectively in polar conditions.

Interesting facts

Interesting Facts about 2-methyl-1H-indole and 5-methyl-1H-indole

2-methyl-1H-indole and 5-methyl-1H-indole are fascinating organic compounds belonging to the indole family. This family of compounds is known for its rich structural diversity and significant role in biological systems. Here are some intriguing aspects of these compounds:

  • Structural Insight: Both compounds feature a methyl group attached to the indole ring at different positions, leading to distinct properties and potential applications.
  • Biological Relevance: Indoles are often found in various natural products and are known for their occurrence in many biological molecules like tryptophan, an essential amino acid.
  • Pharmaceutical Potential: Compounds in the indole class, including 2-methyl-1H-indole and 5-methyl-1H-indole, have garnered interest in medicinal chemistry for their ability to act as precursors to biologically active compounds. They have been studied for their potential anti-inflammatory and anti-cancer properties.
  • Electronic Properties: The presence and positioning of the methyl group can influence the electronic properties of these molecules, therefore affecting their reactivity and interaction with other compounds.
  • Research Applications: These compounds serve as important intermediates in synthetic organic chemistry, aiding in the development of novel materials and pharmaceuticals.

As a member of the indole derivatives, 2-methyl-1H-indole and 5-methyl-1H-indole showcase the beauty of organic chemistry, emphasizing the intricate link between structure and function in the chemical world. Their versatility continues to inspire research across numerous scientific disciplines.

Synonyms
27323-28-0
1H-Indole, methyl-
SCHEMBL29534949
DTXSID50950041
2-Methyl-1H-indole--5-methyl-1H-indole (1/1)