Skip to main content

Modafinil

ADVERTISEMENT
Identification
Molecular formula
C15H15NO2
CAS number
68693-11-8
IUPAC name
2-methyl-2-(1-naphthyl)-4-(1-piperidyl)butanamide
State
State

At room temperature, Modafinil is typically in a solid state as a crystalline powder.

Melting point (Celsius)
165.00
Melting point (Kelvin)
438.15
Boiling point (Celsius)
313.00
Boiling point (Kelvin)
586.15
General information
Molecular weight
273.35g/mol
Molar mass
273.3530g/mol
Density
1.3000g/cm3
Appearence

Modafinil appears as a white to off-white crystalline powder. It is practically insoluble in water and sparingly soluble in acetone and methanol.

Comment on solubility

Solubility of 2-methyl-2-(1-naphthyl)-4-(1-piperidyl)butanamide

The solubility of 2-methyl-2-(1-naphthyl)-4-(1-piperidyl)butanamide can be described through various considerations:

  • Polarity: This compound exhibits significant non-polar characteristics due to the presence of the naphthyl group, which can hinder its overall solubility in polar solvents like water.
  • Solvent Compatibility: While it may have limited solubility in aqueous environments, 2-methyl-2-(1-naphthyl)-4-(1-piperidyl)butanamide is more likely to dissolve well in organic solvents such as ethanol, DMSO, or acetone due to its hydrophobic characteristics.
  • Temperature Influence: As with many compounds, increasing the temperature can enhance solubility, making it possible to dissolve higher quantities in suitable solvents as thermal energy helps overcome intermolecular forces.
  • pH Dependency: The ionization state of the compound can also alter solubility; thus, adjusting the pH of the solution may facilitate the dissolution process, particularly in cases involving protonation or deprotonation of functional groups.

In summary, while 2-methyl-2-(1-naphthyl)-4-(1-piperidyl)butanamide may show limited water solubility, it possesses potential for solubility in various organic solvents, and its solubility can be influenced by factors such as temperature and pH.

Interesting facts

Interesting Facts about 2-methyl-2-(1-naphthyl)-4-(1-piperidyl)butanamide

2-methyl-2-(1-naphthyl)-4-(1-piperidyl)butanamide is a fascinating organic compound that exhibits both structural complexity and functional potential. Below are some engaging insights into this compound:

  • Structure & Functionality: This compound incorporates a variety of functional groups, characterized by a unique interaction between the naphthyl moiety and the piperidine ring. The presence of these groups contributes to its biological activity, making it a valuable subject of study in medicinal chemistry.
  • Pharmacological Relevance: Compounds like this one are often investigated for their potential therapeutic effects. They may exhibit properties such as anti-inflammatory, analgesic, or even antidepressant effects, making them candidates for further research in drug development.
  • Chemistry in Action: The synthesis of this compound typically involves advanced organic synthesis techniques. Understanding the reaction mechanisms can provide valuable insight into creating similar compounds with tailored properties.
  • Research Applications: Compounds with naphthyl and piperidine derivatives are often studied for their interactions in complex biological pathways. Their study can shed light on the mechanistic aspects of neurotransmission and their potential implications in treating neurological disorders.
  • Analytical Studies: Scientists employ various analytical techniques, such as NMR spectroscopy and mass spectrometry, to determine the structure and purity of this compound. These analyses are essential in confirming the efficacy of synthetic routes.

In summary, 2-methyl-2-(1-naphthyl)-4-(1-piperidyl)butanamide is more than just a chemical entity; it embodies the intersection of organic chemistry and pharmacology, paving the way for innovations in therapeutic agents. As research continues, it holds the promise of uncovering new avenues in medicinal chemistry.

Synonyms
1505-98-2
2-methyl-2-naphthalen-1-yl-4-piperidin-1-ylbutanamide
alpha-Methyl-alpha-(2-piperidinoethyl)-1-naphthaleneacetamide
BRN 1260015
Butyramide, 2-methyl-2-(1-naphthyl)-4-piperidino-
alpha-Methyl-alpha-(2-piperidinoethyl)-1-naphthylacetamide
1-NAPHTHALENEACETAMIDE, alpha-METHYL-alpha-(2-PIPERIDINOETHYL)-
DTXSID00933980
2-Methyl-2-(naphthalen-1-yl)-4-(piperidin-1-yl)butanimidic acid