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Fenofibric acid

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Identification
Molecular formula
C17H16O4
CAS number
42017-89-0
IUPAC name
2-methyl-2-(4-tetralin-1-ylphenoxy)propanoic acid
State
State

In standard conditions, fenofibric acid is a solid. It maintains its structural integrity with no tendency to liquefy or vaporize under normal environmental temperatures.

Melting point (Celsius)
158.00
Melting point (Kelvin)
431.15
Boiling point (Celsius)
429.00
Boiling point (Kelvin)
702.15
General information
Molecular weight
318.36g/mol
Molar mass
318.3640g/mol
Density
1.2110g/cm3
Appearence

Fenofibric acid typically appears as a white to off-white powder. It is crystalline in nature and does not exhibit any distinct smell. The powder is usually free-flowing and readily used for pharmaceutical preparations.

Comment on solubility

Solubility of 2-methyl-2-(4-tetralin-1-ylphenoxy)propanoic acid

The solubility of 2-methyl-2-(4-tetralin-1-ylphenoxy)propanoic acid presents unique characteristics that can be intriguing to explore. This compound largely depends on the nature of its functional groups and its molecular structure, which influences its interaction with solvents.

Key Factors Influencing Solubility:

  • Molecular Structure: The presence of a carboxylic acid group typically enhances solubility in polar solvents, while the bulky tetralin moiety can impede solvation.
  • Solvent Polarity: In general, polar solvents like water may dissolve the acidic form, while non-polar solvents might better solubilize the bulkier components.
  • Temperature: Higher temperatures often increase solubility as kinetic energy allows for greater molecular interactions.

Measurements indicate that 2-methyl-2-(4-tetralin-1-ylphenoxy)propanoic acid has moderate solubility in organic solvents but may have limited solubility in aqueous environments. As with many organic compounds, the interaction and solubility behavior can vary significantly depending on the conditions, making it essential to consider the solvent system during practical applications.

In summary, understanding the solubility profile of this compound is crucial for its utilization in various chemical reactions and applications. To quote a common saying in chemistry, “Like dissolves like,” which underscores the importance of matching solvent and solute characteristics for optimal solubility.

Interesting facts

Interesting Facts about 2-Methyl-2-(4-tetralin-1-ylphenoxy)propanoic Acid

2-Methyl-2-(4-tetralin-1-ylphenoxy)propanoic acid is a fascinating compound from the family of larger organic molecules known for its diverse applications and biochemical relevance. Here are some intriguing points to consider:

  • Pharmaceutical Significance: This compound exhibits potential therapeutic properties, making it important in medicinal chemistry research. Its structure is related to anti-inflammatory and analgesic agents.
  • Complex Hydrocarbon Structure: The presence of a tetralin moiety adds considerable complexity to its molecular architecture. Tetralin is a bicyclic compound, which is significant in organic synthesis and is often used as a solvent.
  • Mechanicity: The phenoxy group enhances the reactivity of the compound, making it a versatile building block in chemical synthesis. Scientists explore its reactivity in various chemical reactions, which contributes to the vast field of organic chemistry.
  • Environmental Impact: Compounds like this one are often examined for their stability and persistence in environmental contexts. Understanding their degradation pathways is crucial for assessing their ecological footprint.
  • Field of Study: Researchers in organic chemistry and pharmaceutical chemistry are particularly interested in such compounds, as they contribute to the development of new drugs and materials. The study of secondary metabolites in plants often leads scientists to explore structurally similar compounds.

As we continue to investigate compounds like 2-methyl-2-(4-tetralin-1-ylphenoxy)propanoic acid, one underlying theme becomes clear: the intricate relationship between structure and function in chemistry. Each functional group can impart unique properties that may lead to innovative applications in various fields.

Ultimately, this compound serves as a reminder of the beauty and complexity inherent in the molecular world, showcasing how even minor modifications can lead to significant changes in reactivity and biological activity.

Synonyms
Nafenopin
3771-19-5
Melipan
Nafenoic acid
2-Methyl-2-(4-(1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy)propanoic acid
Nafenopine
Nafenopinum
Nafenopino
SU-13437
Nafenopine [INN-French]
Nafenopinum [INN-Latin]
Nafenopino [INN-Spanish]
Ciba 13437 SU
CCRIS 421
Nafenopin [USAN:INN:BAN]
nafenopina
2-methyl-2-[4-(1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy]propanoic acid
C 13437 SU
BRN 2005820
DTXSID8020911
SU 13437
CHEBI:77649
CH 13-437
NAFENOPIN [INN]
NAFENOPIN [IARC]
NAFENOPIN [USAN]
093W78U96W
2-Methyl-2-(p-(1,2,3,4-tetrahydro-1-naphthyl)phenoxy)propionic acid
DTXCID40911
Propanoic acid, 2-methyl-2-(4-(1,2,3,4-tetrahydro-1-naphthalenyl)phenoxy)-
2-Methyl-2-(4-(1,2,3,4-tetrahydro-1-naphthalenyl)phenoxy)propanoic acid
2-Methyl-2-(4-(1,2,3,4-tetrahydro-1-naphthyl)phenoxy)propanoic acid
alpha-Methyl-alpha-(p-1,2,3,4-tetrahydronaphth-1-ylphenoxy)propionic acid
NAFENOPIN (IARC)
Nafenopine (INN-French)
Nafenopinum (INN-Latin)
Nafenopino (INN-Spanish)
Propionic acid, 2-methyl-2-(p-(1,2,3,4-tetrahydro-1-naphthyl)phenoxy)-
dl-Nafenopin
Acid, Nafenoic
Propanoic acid, 2-methyl-2-[4-(1,2,3,4-tetrahydro-1-naphthalenyl)phenoxy]-
Propionic acid, 2-methyl-2-[p-(1,2,3,4-tetrahydro-1-naphthyl)phenoxy]-
2-methyl-2-(4-(1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy)propionic acid
2-methyl-2-(p-(1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy)propanoic acid
2-methyl-2-(p-(1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy)propionic acid
2-methyl-2-[4-(1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy]propionic acid
2-methyl-2-[p-(1,2,3,4-tetrahydro-1-naphthyl)phenoxy]propionic acid
2-methyl-2-[p-(1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy]propanoic acid
2-methyl-2-[p-(1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy]propionic acid
D,L-nafenopin
rac-2-methyl-2-(4-(1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy)propanoic acid
rac-2-methyl-2-[4-(1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy]propanoic acid
(+-)-nafenopin
CHEBI:7449
CIBA 13437SU
CIBA 13,437SU
CIBA 13,437 SU
C 13437SU
SU 13.437
PROPIONIC ACID, 2-METHYL-2-(P-(1,2,3,4-TETRAHYDRO-1-NAPHTHYL)PHENOXY-
NCGC00160353-01
TPIA
2-methyl-2-{[4-(1,2,3,4-tetrahydronaphthalen-1-yl)phenyl]oxy}propanoic acid
2-methyl-2-(4-(1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy)propanoic acid; 2-Methyl-2-(4-(1,2,3,4-tetrahydro-1-naphthyl)phenoxy)propanoic acid; 2-Methyl-2-(p-(1,2,3,4-tetrahydro-1-naphthyl)phenoxy)propionic acid; alpha-Methyl-alpha-(p-1,2,3,4-tetrahydronaphth-1-ylphenoxy)propionic acid; BRN 2005820; C 13437 SU
CH 13437
CH-13437
UNII-093W78U96W
Nafenopin (USAN/INN)
SCHEMBL184232
CHEMBL1909070
Tox21_111758
MFCD00865724
AKOS000280603
AKOS027425187
AS-56090
CAS-3771-19-5
D05102
S12098
SR-01000945048
2-methyl-2-(4-tetralin-1-ylphenoxy)propanoic acid
Q6958167
SR-01000945048-1