Skip to main content

Quinuclidine

ADVERTISEMENT
Identification
Molecular formula
C7H13N
CAS number
100-76-5
IUPAC name
2-methyl-2-azabicyclo[2.2.1]heptane
State
State
Quinuclidine is a solid at room temperature. It is commonly found in its crystalline form at ambient conditions.
Melting point (Celsius)
157.50
Melting point (Kelvin)
430.65
Boiling point (Celsius)
149.00
Boiling point (Kelvin)
422.15
General information
Molecular weight
111.18g/mol
Molar mass
111.1830g/mol
Density
1.0213g/cm3
Appearence

Quinuclidine is typically found as a white crystalline powder. It is hygroscopic in nature, meaning it can absorb moisture from the air. The crystals may appear slightly translucent and can be found in larger crystalline form or as a fine powder.

Comment on solubility

Solubility of 2-methyl-2-azabicyclo[2.2.1]heptane

2-methyl-2-azabicyclo[2.2.1]heptane, also known as a bicyclic amine, exhibits notable solubility characteristics that can be influenced by various factors. Consider the following points regarding its solubility:

  • Polar Nature: Due to the presence of the nitrogen atom in its structure, 2-methyl-2-azabicyclo[2.2.1]heptane displays a degree of polarity, which often contributes to its solubility in polar solvents.
  • Non-Polar Solvents: While it shows some solubility in polar solvents like water, it may also dissolve in non-polar solvents to a lesser extent due to its bicyclic framework.
  • Hydrogen Bonding: The nitrogen atom may enhance interactions through hydrogen bonding, specifically in aqueous solutions, which can aid in solubility in water and other polar solvents.
  • Temperature Dependency: The solubility can vary significantly with temperature; generally, higher temperatures increase solubility for many organic compounds.

In summary, the solubility of 2-methyl-2-azabicyclo[2.2.1]heptane can be described as being reasonably soluble in polar solvents while showing some capability in non-polar environments. This versatility makes it an interesting compound for various applications in chemistry.

Interesting facts

Interesting Facts about 2-methyl-2-azabicyclo[2.2.1]heptane

The compound 2-methyl-2-azabicyclo[2.2.1]heptane is a fascinating molecule that is often studied in the context of organic chemistry and medicinal applications. This bicyclic compound features a unique structure that offers a variety of intriguing characteristics and potential uses.

Unique Structural Features

  • Bicyclic Framework: The compound is structured as a bicyclic amine, with the nitrogen atom incorporated into the bicyclic framework, which provides interesting stereochemistry.
  • Methyl Substitution: The presence of a methyl group at the 2-position alters both its chemical reactivity and its physical properties, making it a valuable subject of study in organic synthesis.
  • Azabicyclic Nature: The azabicyclic structure contributes to its potential biological activity, as nitrogen-containing compounds often exhibit interesting pharmacological properties.

Potential Applications

This compound has garnered attention for its applications in various fields:

  • Pharmaceutical Development: Compounds with similar bicyclic structures are often utilized as scaffolds in drug design, particularly in the development of analgesics and other therapeutic agents.
  • Chemistry Education: Understanding the synthesis and reactions of 2-methyl-2-azabicyclo[2.2.1]heptane provides key insights into organic reaction mechanisms and stereochemistry, proving beneficial for students learning advanced organic chemistry.

Quote to Reflect On

As the chemist Linus Pauling said, "The best way to have a good idea is to have lots of ideas." The exploration of unique compounds like 2-methyl-2-azabicyclo[2.2.1]heptane certainly aligns with this sentiment, stimulating further inquiry and innovation in chemical research.

In summary, the structure and potential applications of 2-methyl-2-azabicyclo[2.2.1]heptane make it a subject worthy of exploration in both academic and practical contexts. Its distinctive features not only reveal the complexities of organic chemistry but also pave the way for new discoveries in medicinal chemistry.

Synonyms
Thancat AN 10
2-Methyl-2-azanorbornane
2-Methyl-2-azabicyclo[2.2.1]heptane
4524-95-2
2-Azabicyclo[2.2.1]heptane, 2-methyl-
NSC 94106
2-Methyl-2-azabicyclo(2.2.1)heptane
BRN 1340573
2-AZABICYCLO(2.2.1)HEPTANE, 2-METHYL-
DTXSID00884084
EC 404-810-9
DTXCID201023554
2-Azabicyclo2.2.1heptane, 2-methyl-
404-810-9
NSC94106
SCHEMBL152126
LLAMAEIOZLEXMF-UHFFFAOYSA-N
NSC-94106
NS00001827