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Pemoline

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Identification
Molecular formula
C13H17N2O
CAS number
2152-34-3
IUPAC name
2-methyl-2-phenyl-4-(1-piperidyl)butanamide
State
State

At room temperature, pemoline is typically found as a solid in the form of a crystalline powder. It is utilized in solid dosage forms for medical applications.

Melting point (Celsius)
172.00
Melting point (Kelvin)
445.15
Boiling point (Celsius)
315.90
Boiling point (Kelvin)
589.10
General information
Molecular weight
218.28g/mol
Molar mass
218.2810g/mol
Density
1.1490g/cm3
Appearence

Pemoline typically appears as a white or slightly off-white crystalline powder. It may also occur in the form of solid granules, typically used for pharmaceutical preparations.

Comment on solubility

Solubility of 2-methyl-2-phenyl-4-(1-piperidyl)butanamide

The solubility of 2-methyl-2-phenyl-4-(1-piperidyl)butanamide in different solvents can provide valuable insights into its potential applications and interactions. Understanding its solubility characteristics is crucial in fields such as pharmacology and materials science.

General Solubility Behavior

This compound, due to its amide functional group, typically exhibits the following solubility traits:

  • Polar Solvents: It is likely to have moderate to good solubility in polar solvents like water and alcohols due to hydrogen bonding capabilities.
  • Non-Polar Solvents: Conversely, its solubility in non-polar solvents may be limited because of its polar functional groups, which can create incompatibility with hydrophobic environments.
  • Temperature Dependence: As with many compounds, solubility can also be temperature-dependent, often increasing with temperature in solvents where it is already soluble.

Factors Influencing Solubility

Several factors may affect the solubility of 2-methyl-2-phenyl-4-(1-piperidyl)butanamide:

  • Ionization: The pH of the solution can significantly influence the degree of ionization of the amide group.
  • Encapsulation: The potential for the compound to form complexes with other molecules can enhance or inhibit its solubility.
  • Structural Interactions: Structural features such as steric hindrance may affect how well the compound interacts with solvent molecules.

Overall, exploring the solubility of this compound can lead to better understanding and guidance for its practical uses in various applications. As "like dissolves like," knowing the types of solvents where it is soluble can help distinguish its behavior in different chemical environments.

Interesting facts

Interesting Facts about 2-methyl-2-phenyl-4-(1-piperidyl)butanamide

The compound 2-methyl-2-phenyl-4-(1-piperidyl)butanamide is a fascinating member of the amide family, known for its unique structural features and biological activities. Here are some noteworthy aspects of this compound:

  • Structural Diversity: The presence of a piperidine ring in its structure contributes to the compound's structural complexity and potential biological interactions.
  • Biological Activity: Compounds like this one are often investigated for their potential pharmacological effects, particularly in the fields of neuroscience and medicinal chemistry.
  • Synthetic Routes: The synthesis of 2-methyl-2-phenyl-4-(1-piperidyl)butanamide can involve various organic reactions, showcasing the intricacies of organic synthesis and the creativity of chemists.
  • Applications in Research: It may serve as a valuable template for designing new drugs, especially in the search for compounds that can act on specific receptors or enzymes in the body.
  • Interdisciplinary Connections: The study of this compound connects multiple scientific disciplines, including organic chemistry, pharmacology, and biochemistry, emphasizing the collaborative nature of modern scientific research.

This compound exemplifies the intricate relationship between chemical structure and biological function, making it an important subject of study for those interested in drug design and the development of therapeutic agents.

As chemists delve deeper into understanding compounds like 2-methyl-2-phenyl-4-(1-piperidyl)butanamide, they uncover not just the potential for new applications but also the profound implications of molecular interactions in living systems. It's a perfect example of how a single compound can have a ripple effect throughout various fields of science!

Synonyms
2977-20-0
BRN 1348166
BUTYRAMIDE, 2-METHYL-2-PHENYL-4-PIPERIDINO-
alpha-Methyl-alpha-(2-piperidinoethyl)phenylacetamide
DTXSID20952198
2-Methyl-2-phenyl-4-(piperidin-1-yl)butanimidic acid