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alpha-Methylbenzeneacetic acid

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Identification
Molecular formula
C10H12O2
CAS number
492-37-5
IUPAC name
2-methyl-2-phenyl-propanoic acid
State
State

At room temperature, this compound is a solid. It is crystalline in nature, which is typical for many carboxylic acids, especially those containing aromatic rings.

Melting point (Celsius)
116.00
Melting point (Kelvin)
389.00
Boiling point (Celsius)
273.00
Boiling point (Kelvin)
546.00
General information
Molecular weight
164.21g/mol
Molar mass
164.2070g/mol
Density
1.0460g/cm3
Appearence

The compound typically appears as a white crystalline solid. It has a characteristic aromatic odor that is often associated with benzene derivatives.

Comment on solubility

Solubility of 2-methyl-2-phenyl-propanoic acid

The solubility of 2-methyl-2-phenyl-propanoic acid (also known as 2-Methyl-2-phenylpropanoic acid) can be influenced by various factors, including temperature, pH, and solvent choice. This compound is a carboxylic acid, and such acids generally exhibit certain solubility characteristics:

  • Polar Nature: Due to its carboxylic acid functional group, it has the ability to form hydrogen bonds, enhancing its solubility in polar solvents like water.
  • Solvent Polarity: It displays increased solubility in organic solvents such as ethanol, methanol, and acetone, which can accommodate its hydrophobic aromatic character.
  • Temperature Effects: Typically, an increase in temperature leads to higher solubility. The solubility of 2-methyl-2-phenyl-propanoic acid may increase significantly at elevated temperatures.

However, it is worth noting that the actual solubility can vary and is quantitatively dependent on specific conditions. As a general guideline, carboxylic acids with larger hydrophobic groups tend to have lower solubility in water compared to more polar, smaller acids. Therefore, while 2-methyl-2-phenyl-propanoic acid is expected to be somewhat soluble in water, it will have greater solubility in more organic or less polar environments, allowing it to participate effectively in various chemical reactions.

Interesting facts

Interesting Facts about 2-Methyl-2-phenyl-propanoic Acid

2-Methyl-2-phenyl-propanoic acid, often referred to in the scientific community as an important organic compound, presents a fascinating array of characteristics and applications. Here are some noteworthy points about this compound:

  • Synthetic Versatility: This compound serves as a precursor in organic synthesis, particularly in the production of various pharmaceuticals and agrochemicals, highlighting its significance in medicinal chemistry.
  • Chiral Properties: The presence of chirality in 2-methyl-2-phenyl-propanoic acid allows for the existence of enantiomers, which can exhibit different biological activities. This aspect is crucial in drug development where the effectiveness of each enantiomer can diverge dramatically.
  • Acid-Base Behavior: As a carboxylic acid, 2-methyl-2-phenyl-propanoic acid exhibits typical acid-base properties, contributing to its utility in various reactions and enhancing its role as a reaction catalyst.
  • Natural Occurrence: Interestingly, certain derivatives of 2-methyl-2-phenyl-propanoic acid can be found in nature, hinting at its potential biological significance and applications in natural product synthesis.
  • Regulatory Considerations: The use of this compound in industrial processes is often subject to regulatory scrutiny, especially regarding its environmental impact and safety profile. Hence, understanding its properties is vital for responsible handling.

In summary, 2-methyl-2-phenyl-propanoic acid is not just a simple organic molecule; it plays a critical role in various fields from pharmaceuticals to environmental chemistry. As chemists explore its potential, they unlock further understanding of its applications and implications in science.


Synonyms
2-methyl-2-phenylpropanoic acid
2-Phenylisobutyric acid
alpha,alpha-DIMETHYLPHENYLACETIC ACID
DR8HUH2GYK
UNII-DR8HUH2GYK
Hydratropic acid, .alpha.-methyl-
2-phenyl-2-methylpropionic acid
EINECS 212-556-3
NSC-28952
NSC-29095
.alpha.,.alpha.-Dimethylphenylacetic acid
.alpha.,.alpha.-Dimethylbenzeneacetic acid
YYEROYLAYAVZNW-UHFFFAOYSA-
Benzeneacetic acid, .alpha.,.alpha.-dimethyl-
DTXSID90231907
EC 212-556-3
alpha,alpha-dimethylbenzeneacetic acid
NSC 28952
NSC 29095
benzeneacetic acid, alpha,alpha-dimethyl-
2,2-DIMETHYL-2-PHENYLACETIC ACID
DTXCID80154398
HYDRATROPIC ACID, ALPHA-METHYL-
212-556-3
inchi=1/c10h12o2/c1-10(2,9(11)12)8-6-4-3-5-7-8/h3-7h,1-2h3,(h,11,12)
826-55-1
2-Methyl-2-phenylpropionic acid
MFCD00014332
Dimethylphenylacetic acid
2-methyl-2-phenyl-propionic acid
Benzeneacetic acid,.alpha.-dimethyl-
Propionic acid, 2-methyl-2-phenyl-
.alpha.-Toluic acid,.alpha.-dimethyl-
TH 4161
Phenylisobuttersaure
phenylisobutyric acid
SCHEMBL6571
A,A-Dimethylbenzeneacetic acid
2-methyl-2-phenyl propanoic acid
2-methyl-2-phenyl- propionic acid
2,2-dimethyl-2-phenyl-acetic acid
ALBB-023531
NSC28952
NSC29095
AC-370
alpha, alpha-dimethylphenylacetic acid
AKOS000121417
CS-W004146
FP26983
alpha , alpha -Dimethylphenylacetic acid
AS-10791
SY001281
DB-056644
2-Methyl-2-phenylpropanoic acid, AldrichCPR
NS00008935
P1409
EN300-21181
L10018
AE-562/43450611
Q27276560
Z104493600
a,a-Dimethylbenzeneacetic acid;a-Methylhydratropic acid;2,2-Dimethyl-2-phenylacetic acid