Interesting facts
Interesting Facts about 2-methyl-3,4-dihydro-1H-isoquinoline
2-methyl-3,4-dihydro-1H-isoquinoline is a unique compound that belongs to the isoquinoline class of alkaloids, which are well-known for their diverse biological activities. Here are some intriguing aspects of this compound:
- Structural Significance: The structure of 2-methyl-3,4-dihydro-1H-isoquinoline features a bicyclic ring system that is integral to many natural products. Its construction allows it to participate in various chemical reactions, enhancing its utility in organic synthesis.
- Biological Activity: Isoquinolines and their derivatives are abundant in nature, and they often exhibit significant pharmacological properties. Compounds related to 2-methyl-3,4-dihydro-1H-isoquinoline have been studied for their potential use as antibiotics, antioxidants, and in the treatment of neuroses.
- Synthesis Techniques: Numerous synthetic pathways exist to produce 2-methyl-3,4-dihydro-1H-isoquinoline, including the use of Diels-Alder reactions and metal-catalyzed couplings. These techniques illustrate the versatility and excitement surrounding modern synthetic chemistry.
- Research Implications: Continuous research in medicinal chemistry focuses on isoquinoline derivatives, including 2-methyl-3,4-dihydro-1H-isoquinoline, due to their roles in drug discovery. Notably, they are often investigated for their effectiveness against various diseases like cancer and neurological disorders.
- Cultural Relevance: Isoquinoline derivatives play a role in traditional medicine in several cultures, further showcasing their importance beyond the laboratory. Their study often bridges chemistry with pharmacognosy, revealing traditional applications supported by modern science.
In summary, 2-methyl-3,4-dihydro-1H-isoquinoline serves as a fascinating subject of study due to its intricate structure and potential therapeutic applications. As research unfolds, this compound may pave the way for novel discoveries in both chemical synthesis and medicinal use.
Synonyms
2-Methyl-1,2,3,4-tetrahydroisoquinoline
1612-65-3
ISOQUINOLINE, 1,2,3,4-TETRAHYDRO-2-METHYL-
1,2,3,4-Tetrahydro-2-methylisoquinoline
BRN 0127214
DTXSID00167086
5-20-06-00321 (Beilstein Handbook Reference)
DTXCID4089577
inchi=1/c10h13n/c1-11-7-6-9-4-2-3-5-10(9)8-11/h2-5h,6-8h2,1h
2-methyl-3,4-dihydro-1H-isoquinoline
CHEMBL22053
2-Methyl-1,2,3,4-tetrahydro-isoquinoline
CHEMBL545413
MFCD00040623
SCHEMBL98108
BDBM50014651
AKOS002314902
DS-18036
DB-330450
CS-0186657
O10829
EN300-7691375
2-Methyl-1,2,3,4-tetrahydro-isoquinoline; hydrochloride
2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium chloride
Solubility of 2-methyl-3,4-dihydro-1H-isoquinoline
2-methyl-3,4-dihydro-1H-isoquinoline is an intriguing compound when it comes to its solubility characteristics. It exhibits the following key points:
As a rule of thumb, compounds with hydrophobic structures like 2-methyl-3,4-dihydro-1H-isoquinoline tend to be less soluble in water but find better solubility in non-polar solvents. This trend can be attributed to the like dissolves like principle, highlighting the interaction between solute and solvent molecules.
In summary, while 2-methyl-3,4-dihydro-1H-isoquinoline demonstrates a level of solubility in organic solvents, researchers must take care in selecting the appropriate solvent for their needs due to its limited water solubility.