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Fentanyl

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Identification
Molecular formula
C22H28N2O
CAS number
437-38-7
IUPAC name
2-methyl-4-morpholino-2-(1-naphthyl)butanamide
State
State

At room temperature, fentanyl generally exists as a solid (powder form). However, for pharmaceutical use, it is often dissolved in solution for injection or used in transdermal patches.

Melting point (Celsius)
87.50
Melting point (Kelvin)
360.65
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
336.47g/mol
Molar mass
336.4700g/mol
Density
1.3437g/cm3
Appearence

Fentanyl is typically encountered as a white to off-white powder. It can also appear in a slightly yellow tint due to impurities when synthesized in illicit conditions. In medical settings, it is often used in a clear, colorless liquid form in injections or transdermal patches.

Comment on solubility

Solubility of 2-methyl-4-morpholino-2-(1-naphthyl)butanamide

The solubility of 2-methyl-4-morpholino-2-(1-naphthyl)butanamide can be influenced by several factors due to its unique molecular structure. Here are some insights:

  • Solvent Compatibility: This compound is likely to exhibit varying degrees of solubility in different solvents. Non-polar solvents might not dissolve it well due to its polar morpholino group, while polar solvents such as methanol or ethanol may enhance its solubility.
  • Temperature Dependency: Generally, the solubility of organic compounds can increase with temperature. Therefore, raising the temperature when dissolving this compound might yield better results.
  • pH Influence: If in an aqueous solution, the pH of the environment could play a significant role. The morpholino group can act as a weak base, which may affect its ionization and, subsequently, its solubility.
  • Concentration and Saturation: It is also essential to consider that at higher concentrations, the solubility may reach a saturation point where no further dissolution occurs, thereby requiring careful management during experimentation.

In summary, while the solubility of 2-methyl-4-morpholino-2-(1-naphthyl)butanamide may be moderate in some solvents, it is pivotal to conduct solubility studies to ascertain the optimal conditions for its dissolution.

Interesting facts

Interesting Facts about 2-methyl-4-morpholino-2-(1-naphthyl)butanamide

2-methyl-4-morpholino-2-(1-naphthyl)butanamide, often referred to simply as a morpholino compound, has gained attention in the fields of pharmacology and medicinal chemistry due to its intriguing structural attributes and biological activities. Here are some engaging insights:

  • Structure Matters: The presence of both a morpholine ring and a naphthyl group in its structure contributes to its unique physicochemical properties, offering potential for various biological interactions.
  • Pharmacological Potential: This compound has been investigated for its role in the treatment of various diseases. Its ability to modulate biological pathways makes it a candidate for drug development.
  • Research Uses: Beyond its therapeutic implications, it serves as a valuable tool in structure-activity relationship (SAR) studies, allowing researchers to explore and optimize interactions at the molecular level.
  • Mechanism of Action: Understanding the mechanism of action of this compound can provide insights into how it influences cellular processes, leading to its potential efficacy in treating specific conditions.
  • Versatility: Its diverse functional groups make it a versatile building block in organic synthesis, potentially leading to the creation of novel derivatives with enhanced properties.

In conclusion, 2-methyl-4-morpholino-2-(1-naphthyl)butanamide exemplifies how a single compound can open up numerous avenues for exploration in both research and practical applications. As researchers continue to unveil its secrets, the potential for groundbreaking discoveries remains high!

Synonyms
1506-01-0
2-methyl-4-morpholin-4-yl-2-naphthalen-1-ylbutanamide
alpha-Methyl-alpha-(2-morpholinoethyl)-1-naphthaleneacetamide
BRN 1086240
Butyramide, 2-methyl-4-morpholino-2-(1-naphthyl)-
alpha-Methyl-alpha-(2-morpholinoethyl)-1-naphthylacetamide
1-NAPHTHALENEACETAMIDE, alpha-METHYL-alpha-(2-MORPHOLINOETHYL)-
DTXSID70934005
2-Methyl-4-(morpholin-4-yl)-2-(naphthalen-1-yl)butanimidic acid