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N-ethylmaleimide

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Identification
Molecular formula
C6H7NO2
CAS number
128-53-0
IUPAC name
2-methyl-4,5,6,7-tetrahydroisoindole-1,3-dione
State
State

At room temperature, N-ethylmaleimide is in a solid state. It is stable under normal temperatures and pressures, but may decompose upon heating, releasing potentially hazardous fumes.

Melting point (Celsius)
44.50
Melting point (Kelvin)
317.65
Boiling point (Celsius)
250.90
Boiling point (Kelvin)
524.05
General information
Molecular weight
125.13g/mol
Molar mass
125.1300g/mol
Density
1.2190g/cm3
Appearence

N-ethylmaleimide is typically a white crystalline solid. It often appears as a colorless to pale yellow crystalline powder. It has a characteristic odor that may be slightly unpleasant.

Comment on solubility

Solubility of 2-methyl-4,5,6,7-tetrahydroisoindole-1,3-dione

2-methyl-4,5,6,7-tetrahydroisoindole-1,3-dione exhibits intriguing solubility characteristics that are worth noting:

  • Solvent-specific solubility: This compound is generally more soluble in organic solvents, such as ethanol and dichloromethane, due to its hydrophobic nature.
  • Low aqueous solubility: When it comes to water solubility, 2-methyl-4,5,6,7-tetrahydroisoindole-1,3-dione is expected to have limited solubility, making it less favorable for reactions in aqueous environments.
  • Temperature dependence: The solubility may vary with temperature; an increase in temperature typically enhances solubility in organic solvents.

As a general rule, compounds that contain substantial hydrophobic regions, such as this isoindole derivative, tend to display reduced solubility in polar solvents like water. Understanding the solubility of this compound can be critical for applications in fields like pharmaceuticals and materials science.

In conclusion, while it may present challenges in aqueous solutions, the solubility profile of 2-methyl-4,5,6,7-tetrahydroisoindole-1,3-dione in organic solvents opens up various avenues for chemical applications and research.

Interesting facts

Interesting Facts about 2-methyl-4,5,6,7-tetrahydroisoindole-1,3-dione

2-methyl-4,5,6,7-tetrahydroisoindole-1,3-dione, often referred to in chemical circles as a complex bicyclic compound, boasts several notable characteristics worth exploring:

  • Diverse Applications: This compound has garnered attention in the fields of medicinal chemistry and drug development. Its unique structure often leads to *bioactivity*, making it a promising candidate for further research.
  • Synthetic Versatility: The synthesis of 2-methyl-4,5,6,7-tetrahydroisoindole-1,3-dione can be achieved through various routes, showcasing its *synthetic versatility*. This adaptability is crucial for tailoring variations that may enhance its properties.
  • Structural Insights: Featuring a bicyclic system, it provides *valuable insights* into how changes in molecular configuration can impact reactivity and biological activity. This aspect is often explored in advanced organic chemistry courses.
  • Research Potential: As a compound that could potentially serve as a scaffold for more complex molecular designs, it presents a large area of *research potential* for students and professionals alike.
  • Natural Analogues: Its structure is reminiscent of several *natural products*, motivating further exploration of its naturally occurring analogs and their biological significance.

"Chemistry is the art of transformation" - this compound exemplifies that art through its diverse structural possibilities and applications.

As we continue to unravel the mysteries behind 2-methyl-4,5,6,7-tetrahydroisoindole-1,3-dione, it stands as a testaments to the dynamic nature of organic compounds and their vast potential within the scientific community.

Synonyms
28839-49-8
N-Methyl-3,4,5,6-tetrahydrophthalimide
BRN 1528408
1-CYCLOHEXENE-1,2-DICARBOXIMIDE, N-METHYL-
N-Methyl-1-cyclophene-1,2-dicarboximide
1H-Isoindole-1,3(2H)-dione, 4,5,6,7-tetrahydro-2-methyl-
DTXSID70183036
N-Methyl-1-cyclohexene-1,2-dicarboximide
RefChem:229641
DTXCID80105527
KQPBJYADGVCRIC-UHFFFAOYSA-N
Phthalimide, 3,4,5,6-tetrahydro-N-methyl-
2-Methyl-4,5,6,7-tetrahydro-1H-isoindole-1,3(2H)-dione
2-methyl-4,5,6,7-tetrahydroisoindole-1,3-dione
S25KLY8TPS
SCHEMBL46223
SCHEMBL585884
2-methyl-2,3,4,5,6,7-hexahydro-1H-isoindole-1,3-dione
4,5,6,7-Tetrahydro-2-methyl-1H-isoindole-1,3(2H)-dione
AKOS006276831
N-Methyl-1,2-dicarboximide 1-cyclohexene
2-Methyl-4,5,6,7-tetrahydro-1H-isoindole-1,3(2H)-dione #