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2-Methyl-5-nitroaniline

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Identification
Molecular formula
C7H8N2O2
CAS number
99-55-8
IUPAC name
2-methyl-5-nitro-aniline
State
State

At room temperature, 2-Methyl-5-nitroaniline is in a solid state. It is known for its crystal-like texture and is not soluble in water, but might dissolve in organic solvents like ethanol or chloroform.

Melting point (Celsius)
121.00
Melting point (Kelvin)
394.15
Boiling point (Celsius)
293.00
Boiling point (Kelvin)
566.15
General information
Molecular weight
152.15g/mol
Molar mass
152.1520g/mol
Density
1.2540g/cm3
Appearence

The compound 2-Methyl-5-nitroaniline is typically found as yellow crystalline solid. The intensity and hue of the yellow might vary slightly based on purity and specific conditions. It is often used in the synthesis of various azo dyes due to its distinct color properties.

Comment on solubility

Solubility of 2-methyl-5-nitro-aniline

2-methyl-5-nitro-aniline, with the chemical formula C7H8N2O2, exhibits interesting solubility characteristics that are essential in various chemical applications. This compound features both hydrophilic and hydrophobic segments, which influence its solubility in different solvents.

Key Solubility Characteristics:

  • Solubility in Water: 2-methyl-5-nitro-aniline is only slightly soluble in water due to its aromatic structure, which limits interaction with polar solvents.
  • Solubility in Organic Solvents: It is highly soluble in organic solvents such as ethanol, acetone, and chloroform. This is largely due to its nonpolar characteristics dominating in nonpolar environments.
  • pH Dependence: The solubility may alter with pH; at different pH levels, the ionization of the amine group may enhance water solubility, making it more bioavailable.

In summary, the solubility of 2-methyl-5-nitro-aniline is solvent-dependent, showcasing a complex interaction between its molecular structure and the properties of potential solvents. As with many aromatic compounds, this aspect plays a crucial role in its practical applications, influencing both reactivity and usability in various chemical processes.

Interesting facts

Interesting Facts about 2-Methyl-5-Nitro-Aniline

2-Methyl-5-nitro-aniline, often abbreviated as 2M5NA, is a fascinating compound in the realm of organic chemistry. Here are some engaging insights that showcase its significance:

  • Component of Dyes: This compound is widely used as an intermediate in the synthesis of various dyes, particularly azo dyes. These dyes are known for their vibrant colors and are integral in the textile industry.
  • Health and Safety Considerations: As with many nitroaniline derivatives, it is essential to handle 2-methyl-5-nitro-aniline with caution. The nitro group can render the compound toxic, and proper safety protocols should always be observed while working with it.
  • Application in Research: Chemists often use this compound as a building block in drug discovery and development. Its unique structure allows researchers to modify it easily, potentially leading to new therapeutic agents.
  • Environmental Impact: The use of nitroanilines in industries raises questions concerning their environmental impact. Awareness of their behavior and degradation in the environment is crucial in ensuring compliance with safety regulations.
  • Synthetic Versatility: The presence of both the methyl and nitro groups on the aromatic ring provides chemists with multiple sites for further substitution reactions, enhancing the versatility of the compound in organic synthesis.

In summary, 2-methyl-5-nitro-aniline serves as a prime example of how a single compound can have diverse applications ranging from dye manufacturing to potential medicinal uses. Its study offers valuable insights into both synthetic methods and environmental chemistry.

Synonyms
2-Methyl-5-nitroaniline
99-55-8
2-Amino-4-nitrotoluene
5-NITRO-O-TOLUIDINE
2-Methyl-5-nitrobenzenamine
Fast Scarlet G
Scarlet G Base
4-Nitro-2-aminotoluene
Devol Scarlet B
PNOT
Fast Scarlet G Base
3-Nitro-6-methylaniline
Diabase Scarlet G
5-Nitro-2-toluidine
Scarlet Base NSP
Benzenamine, 2-methyl-5-nitro-
1-Amino-2-methyl-5-nitrobenzene
Fast Red SG Base
Fast scarlet base G
o-Toluidine, 5-nitro-
6-Methyl-3-nitroaniline
Fast Scarlet Base J
Fast Scarlet J Salt
Fast Scarlet T Base
Lake Scarlet G Base
C.I. Azoic Diazo Component 12
Daito Scarlet Base G
Devol Scarlet G Salt
Diazo Fast Scarlet G
Azofix Scarlet G salt
Fast Scarlet GC Base
Scarlet Base Ciba II
Scarlet Base Irga II
Kayaku Scarlet G Base
Mitsui Scarlet G Base
Azogene Fast Scarlet G
Lithosol Orange R Base
Symulon Scarlet G Base
Amarthol Fast Scarlet G Base
Fast Scarlet G Salt
Hiltonil Fast Scarlet G Base
Naphthanil Scarlet G Base
2-Methyl-5-nitro-benzeneamine
Naphtoelan Fast Scarlet G Base
Sugai Fast Scarlet G Base
Azoene Fast Scarlet GC Base
Azoene Fast Scarlet GC salt
Amarthol Fast Scarlet G salt
5-Nitro-2-methylaniline
Dainichi Fast Scarlet G Base
Hiltonil Fast Scarlet G Salt
Hiltonil Fast Scarlet GC Base
Naphtoelan Fast Scarlet G Salt
5-Nitro-ortho-toluidine
Fast Scarlet M4NT Base
Rcra waste number U181
Azoic Diazo Component 12
NCI-C01843
C.I. 37105
CCRIS 483
o-amino-p-nitrotoluene
CI Azoic Diazo Component 12
fast scarlet mN4t base
HSDB 4144
CI 37105
NSC 8947
EINECS 202-765-8
433MYH2DWM
BRN 0879021
DTXSID4020959
CHEBI:66891
AI3-01557
NSC-8947
Fast Scarlet M 4NT Base
DTXCID60959
Azoic diazo component 12, base
EC 202-765-8
4-12-00-01807 (Beilstein Handbook Reference)
5-NITRO-O-TOLUIDINE [HSDB]
MFCD00007741
5-NITRO-ORTHO-TOLUIDINE [IARC]
2-methyl-5-nitro aniline
5-NITRO-ORTHO-TOLUIDINE (IARC)
CAS-99-55-8
SMR000343278
RCRA waste no. U181
UNII-433MYH2DWM
2-methyl-5-nitrophenylamine
Nitrootoluidine
Conazoic Diazo AB
2Amino4nitrotoluene
4Nitro2aminotoluene
Amino-nitro-toluene
oToluidine, 5nitro
2Methyl5nitroaniline
3Nitro6methylaniline
6Methyl3nitroaniline
C.I. Azoic Diazo Component No. 12
2Methyl5nitrobenzenamine
3-Nitro-6-methylanilin
2-methyl,5-nitroaniline
2-amino-4-nitro toluene
2-amino-4-nitro-toluene
2-methyl-5-nitro-aniline
2-Methyl-5-nitroaniline-
Benzenamine, 2methyl5nitro
WLN: ZR B1 ENW
SCHEMBL2313
Azoene Fast Scarlet G Salt
aniline, 2-methyl-5-nitro-
MLS000517118
MLS002152874
2-Methyl-5-nitro-phenylamine
(2-Methyl-5-nitrophenyl)amine
CHEMBL324642
2-Methyl-5-nitroaniline, 95%
2-Methyl-5-nitroaniline, 98%
4-nitro-2-amino-1-methylbenzene
NSC8947
1-Methyl-2-amino-4-nitrobenzene
2-Methyl-5-nitroaniline, 98+%
HMS2679N16
BCP24941
CS-M3392
STR03005
Tox21_201945
Tox21_300134
STL163886
AKOS000119136
Colour Index Azoic Diazo Component 12
FM33941
SB10516
5-Nitro-o-toluidine, analytical standard
BENZENEAMINE, 2-METHYL-5-NITRO-
NCGC00091592-01
NCGC00091592-02
NCGC00091592-03
NCGC00091592-04
NCGC00254217-01
NCGC00259494-01
AI301557
DB-030868
2-Methyl-5-nitroaniline, analytical standard
N0115
NS00006304
Scarlet Base NSP Sugai Fast Scarlet G Base
EN300-17407
D77508
AH-034/32850060
2-Amino-4-nitrotoluene 10 microg/mL in Acetonitrile
2-Amino-4-nitrotoluene 100 microg/mL in Acetonitrile
Q27135494
Z56926522
F2190-0478
202-765-8