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2-Methyl-5-nitrobenzenesulfonyl chloride

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Identification
Molecular formula
C7H6ClNO4S
CAS number
6362-79-4
IUPAC name
2-methyl-5-nitro-benzenesulfonyl chloride
State
State

At room temperature, 2-Methyl-5-nitrobenzenesulfonyl chloride is in a solid state, specifically existing as a crystalline solid that can vary in color from off-white to yellowish.

Melting point (Celsius)
73.00
Melting point (Kelvin)
346.15
Boiling point (Celsius)
330.00
Boiling point (Kelvin)
603.15
General information
Molecular weight
249.65g/mol
Molar mass
249.6510g/mol
Density
1.5300g/cm3
Appearence

2-Methyl-5-nitrobenzenesulfonyl chloride appears as an off-white to yellowish crystalline solid. Its characteristic crystalline form is often used as one of the identifiers for this compound in laboratory settings.

Comment on solubility

Solubility of 2-methyl-5-nitro-benzenesulfonyl chloride

2-methyl-5-nitro-benzenesulfonyl chloride is an interesting compound when it comes to its solubility characteristics. Its solubility can be understood through several key factors:

  • Polarity: The presence of both the sulfonyl chloride group and nitro group contributes to a significant degree of polarity. This characteristic tends to enhance solubility in polar solvents, such as water and alcohols.
  • Solvent Compatibility: Based on its chemical structure, 2-methyl-5-nitro-benzenesulfonyl chloride is likely to have limited solubility in non-polar solvents, thus making it relatively well-suited for reactions occurring in polar environments.
  • Temperature Influence: As with many organic compounds, the solubility of this compound may increase with temperature. Generally, higher temperatures can disrupt intermolecular interactions and facilitate dissolution.
  • Functional Group Interaction: The sulfonyl chloride functionality may engage in hydrogen bonding with water molecules, enhancing its solubility profile. It is also important to note interactions with other potential solubilizing agents.

In summary, while 2-methyl-5-nitro-benzenesulfonyl chloride may show good solubility in polar solvents, its limited solubility in non-polar environments reflects the impact of its functional groups and molecular structure on solvation processes. Understanding these solubility attributes is crucial for utilizing this compound effectively in various chemical applications.

Interesting facts

Interesting Facts about 2-Methyl-5-nitro-benzenesulfonyl chloride

2-Methyl-5-nitro-benzenesulfonyl chloride is an intriguing compound that belongs to the class of sulfonyl chlorides, often used in various organic synthesis processes. Here are some interesting facts that highlight its significance and applications:

  • Synthesis Versatility: This compound serves as an important building block in synthesizing pharmaceuticals, agrochemicals, and dyes. Its electrophilic nature allows it to participate in various reactions such as nucleophilic substitution.
  • Functionalization Potential: The presence of both a nitro group and a sulfonyl chloride functional group makes it a valuable intermediate for further functionalization in synthetic chemistry.
  • Environmental Considerations: The usage of sulfur-containing compounds is often scrutinized due to environmental concerns. It's essential for chemists to implement green chemistry principles when working with such compounds, ensuring minimal waste and safer handling procedures.
  • Analytical Applications: 2-Methyl-5-nitro-benzenesulfonyl chloride can be employed in analytical chemistry, particularly in the development of reagents for detecting certain functional groups.
  • Pharmaceutical Relevance: Research has indicated that compounds involving this specific sulfonyl chloride can exhibit antimicrobial properties, making it worth studying in the context of drug development.

In conclusion, 2-methyl-5-nitro-benzenesulfonyl chloride is not only an essential precursor in organic synthesis but also paves the way for innovative applications. As Albert Einstein once said, "The important thing is not to stop questioning. Curiosity has its own reason for existing." This compound ignites curiosity and offers a plethora of opportunities for scientists and students eager to explore the fascinating world of chemistry.

Synonyms
121-02-8
2-METHYL-5-NITROBENZENESULFONYL CHLORIDE
2-Methyl-5-Nitrobenzene-1-Sulfonyl Chloride
5-Nitro-o-toluenesulfonyl chloride
Benzenesulfonyl chloride, 2-methyl-5-nitro-
o-Toluenesulfonyl chloride, 5-nitro-
2-Methyl-5-nitrobenzenesulfonylchloride
4-Nitrotoluen-2-sulfochlorid
4-Nitrotoluene-2-sulphonyl chloride
EINECS 204-444-8
4-Nitrotoluen-2-sulfonylchlorid
Y7R9YZ83FS
NSC 49752
4-Nitrotoluen-2-sulfochlorid [Czech]
BRN 2697079
4-Nitrotoluen-2-sulfonylchlorid [Czech]
4-Nitrotoluene-2-sulfonyl chloride
MFCD00051695
NSC-49752
2-METHYL-5-NITROBENZENESULPHONYL CHLORIDE
DTXSID10153096
4-11-00-00236 (Beilstein Handbook Reference)
NSC49752
2-methyl-5-nitro-benzenesulfonyl chloride
UNII-Y7R9YZ83FS
WLN: WSGR B1 ENW
SCHEMBL1026210
DTXCID9075587
3-Nitro-6-methylbenzolsulfochlorid
STR04719
CK2504
STL483081
AKOS001018259
CS-W012885
5-nitro-2-methyl-phenylsulfonyl chloride
2-methyl-5-nitrobenzene sulfonyl chloride
SY070806
2-methyl-5-nitro-benzenesulphonyl chloride
2-methyl-5-nitrobenzene sulphonyl chloride
UPCMLD0ENAT0502-0329:001
2-Methyl-5-Nitrobenzene-1-SulfonylChloride
DB-021360
M2178
NS00023942
EN300-01723
2-Methyl-5-nitrobenzenesulfonyl chloride, 97%
Benzenesulfonyl chloride, 2-methyl-5-nitro-(9CI)
Z56772648
F2190-0571