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2-Methyl-5-phenyl-3,4-dihydroisoquinoline

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Identification
Molecular formula
C16H17N
CAS number
17609-55-7
IUPAC name
2-methyl-5-phenyl-3,4-dihydro-1H-isoquinoline
State
State

At room temperature, 2-Methyl-5-phenyl-3,4-dihydroisoquinoline is typically found in a liquid state, although it may crystallize under certain conditions or temperatures.

Melting point (Celsius)
25.00
Melting point (Kelvin)
298.15
Boiling point (Celsius)
293.40
Boiling point (Kelvin)
566.55
General information
Molecular weight
209.32g/mol
Molar mass
209.2980g/mol
Density
1.0105g/cm3
Appearence

2-Methyl-5-phenyl-3,4-dihydroisoquinoline typically appears as a colorless to pale yellow liquid or solid. Its appearance can vary depending on its specific form and purity. It is not a commonly occurring compound and may not have a highly defined appearance in general chemical literature.

Comment on solubility

Solubility of 2-methyl-5-phenyl-3,4-dihydro-1H-isoquinoline

The solubility of 2-methyl-5-phenyl-3,4-dihydro-1H-isoquinoline in various solvents is a topic of great interest due to its structural characteristics. Generally, this compound exhibits the following solubility behaviors:

  • Non-polar solvents: This compound tends to show relatively good solubility in non-polar solvents such as hexane or toluene due to its hydrophobic aromatic ring.
  • Polar solvents: Conversely, its solubility in polar solvents like water is limited. This is largely attributed to the lack of sufficient polar functional groups within the molecule that can engage in hydrogen bonding with water.
  • Organic solvents: It often dissolves well in organic solvents such as ethanol, methanol, and acetone, which can provide a balance of polar and non-polar interactions.

As a guide, the general rule of thumb for solubility is: "like dissolves like." Therefore, to maximize dissolution, it is advisable to choose solvents with similar properties to the compound’s structure.

In practical applications, understanding solubility is critical for:

  1. Developing effective formulations in pharmaceuticals.
  2. Optimizing extraction processes in chemical syntheses.
  3. Influencing the compound's reactivity and stability in various environments.

In conclusion, the solubility of 2-methyl-5-phenyl-3,4-dihydro-1H-isoquinoline reflects its structural complexities, and careful consideration of solvent choice can significantly impact its applications in chemistry and materials science.

Interesting facts

Exploring 2-methyl-5-phenyl-3,4-dihydro-1H-isoquinoline

2-methyl-5-phenyl-3,4-dihydro-1H-isoquinoline is an intriguing compound belonging to the isoquinoline family, which showcases a rich framework of organic chemistry. Here are some interesting aspects of this compound:

  • Unique Structure: The structure of this isoquinoline derivative highlights both hydrogenation and aromatic systems, making it a subject of interest for studying chemical reactivity and stability.
  • Biological Activity: Compounds like this one have been investigated for their potential pharmacological properties, including neuroprotective effects and activities against various diseases. Isoquinolines often exhibit promising medicinal properties.
  • Synthesis: The synthesis of such compounds can involve intricate methods that showcase multi-step reactions. The presence of both methyl and phenyl groups can influence the compound's reactivity and solubility.
  • Optical Activity: Depending on their structure, isoquinolines can display chirality. This characteristic is critical in the field of medicinal chemistry where the 3D orientation of a compound can significantly affect its efficacy and safety.

Given its fascinating characteristics, 2-methyl-5-phenyl-3,4-dihydro-1H-isoquinoline serves as an essential compound for both research and application in chemistry and pharmacology. Its derivative forms can lead to the development of novel therapeutic agents, making it a compound of great interest.

As scientists continue to unlock the secrets of compounds like this, one might say, “In chemistry, every molecule tells a story.” The potential of isoquinolines could very well lead to new breakthroughs in drug discovery and development.

Synonyms
SCHEMBL14287229