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2-methyladenine

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Identification
Molecular formula
C6H7N5
CAS number
134-41-6
IUPAC name
2-methyl-7H-purin-6-amine
State
State

At room temperature, 2-Methyladenine is found as a solid.

Melting point (Celsius)
235.00
Melting point (Kelvin)
508.15
Boiling point (Celsius)
465.95
Boiling point (Kelvin)
739.10
General information
Molecular weight
149.15g/mol
Molar mass
149.1510g/mol
Density
1.3400g/cm3
Appearence

2-Methyladenine is typically a white to off-white crystalline powder.

Comment on solubility

Solubility of 2-methyl-7H-purin-6-amine

The solubility of 2-methyl-7H-purin-6-amine, often referred to as a derivative of purine, can be described as follows:

  • Solvent Compatibility: This compound is known to exhibit moderate solubility in polar solvents such as water and alcohols. Its structural properties, including the presence of amino and methyl groups, allow for favorable interactions with these solvents.
  • Influencing Factors: The solubility can be significantly impacted by factors such as temperature and pH. Generally, increased temperature leads to increased solubility, which is a common phenomenon observed in many organic compounds.
  • pH Dependency: The solubility might also vary with pH changes due to protonation or deprotonation of functional groups, which can enhance or hinder interaction with the solvent.

As noted in various studies, it has been observed that:

“The solubility behavior of purine derivatives reflects both their structural variants and the solvent system utilized.”

This characteristic chemistry makes 2-methyl-7H-purin-6-amine an interesting subject of study in pharmacology and biochemistry, where solubility plays a crucial role in bioavailability and overall functionality.

Interesting facts

Interesting Facts about 2-Methyl-7H-purin-6-amine

2-Methyl-7H-purin-6-amine, commonly known as 2-methyladenine, is a fascinating compound that belongs to the purine family. This compound plays a crucial role in various biological processes and has garnered attention for its significance in both biochemistry and pharmacology.

Biological Significance

This compound is particularly noteworthy due to its relationship with nucleic acids:

  • Adenine Component: 2-methyladenine is a derivative of adenine, an essential nucleobase found in DNA and RNA. This makes it vital for many cellular processes, including protein synthesis and genetic information storage.
  • Role in Signaling: It is involved in the regulation of various signaling pathways in cells, influencing cellular responses to external stimuli.
  • Impact on Gene Expression: Research indicates that derivatives of adenine can affect gene expression and influence metabolic pathways, which is pivotal in understanding cellular functions.

Applications in Research and Medicine

The importance of 2-methyladenine extends beyond biological functions:

  • Anticancer Research: Studies have shown that methylated purines can play a role in cancer research, potentially leading to the development of new therapeutic agents.
  • Neurological Studies: This compound is also being investigated for its potential effects on the nervous system and could have implications in treating neurodegenerative diseases.
  • Biotechnological Applications: Due to its involvement in nucleic acid interactions, 2-methyladenine is studied for its utility in biotechnological advancements, such as gene editing technologies.

Interesting Tidbits

  • The name "adenine" itself is derived from the word "adenosine" because it was first isolated from animal tissue (i.e., the gland) - hence, the connection to gland.
  • 2-Methyladenine's role in cellular processes showcases the astonishing complexity of life, illustrating how small changes at the molecular level can have profound consequences.
  • Its exploration in various fields of science highlights the *interdisciplinary nature* of modern research, merging chemistry, biology, and medicine.

In conclusion, 2-methyl-7H-purin-6-amine is not just a simple organic compound; it is a pivotal element in the realm of biochemistry with promising applications that could revolutionize our understanding of biology and medicine.

Synonyms
2-Methyl-1H-purin-6-amine
1445-08-5
2-Methyladenine
1H-Purin-6-amine, 2-methyl-
ADENINE, 2-METHYL-
SQ 23354
DTXSID80162731
NSC 26364
DTXCID2085222
1H-Purin-6-amine, 2-methyl-(9CI)
2-methyl-7H-purin-6-amine
2-methyl-9H-purin-6-amine
2-Methyl-6-aminopurine
9H-Purin-6-amine, 2-methyl-
methyladenine
1H-Purin-6-amine, 2-methyl- (9CI)
CHEMBL330897
NSC-26364
2-methyladenin
methyl-3h-adenine
MFCD01674065
J5S7AW6A3C
SCHEMBL19779
2-Methyl-9H-purin-6-ylamine
SMADWRYCYBUIKH-UHFFFAOYSA-N
(2-methyl-9H-purin-6-yl)-amine
BCP29033
NSC26364
BDBM50030961
AKOS006338122
AKOS015905348
AKOS024463815
DS-8040
SQ-23354
SQ 23,354
CS-0186661
1H-Purin-6-amine pound not 2-methyl- (9CI)
D84317
Q15632702