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2-Methyl-8-nitroquinoline

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Identification
Molecular formula
C10H8N2O2
CAS number
5437-39-4
IUPAC name
2-methyl-8-nitro-quinoline
State
State
Solid at room temperature. Typically presented as a crystalline yellow powder, highlighting its aromatic nitro compound nature.
Melting point (Celsius)
119.00
Melting point (Kelvin)
392.15
Boiling point (Celsius)
315.00
Boiling point (Kelvin)
588.15
General information
Molecular weight
188.19g/mol
Molar mass
188.1930g/mol
Density
1.1732g/cm3
Appearence

2-Methyl-8-nitroquinoline appears as a yellow solid. This compound is often used in research settings and is known for its distinct color, which is due to the nitro group's presence on the aromatic ring.

Comment on solubility

Solubility of 2-methyl-8-nitro-quinoline

The solubility of 2-methyl-8-nitro-quinoline, with the chemical formula C10H8N2O2, is a crucial aspect that influences its applications in various fields.

This compound exhibits the following solubility characteristics:

  • Insoluble in water: Due to its relatively hydrophobic nature, 2-methyl-8-nitro-quinoline shows minimal solubility in water.
  • Soluble in organic solvents: It demonstrates better solubility in organic solvents such as ethanol, acetone, and dimethyl sulfoxide (DMSO), making it useful in organic synthesis and characterization.
  • Effect of temperature: Like many organic compounds, increased temperature generally enhances its solubility in organic solvents.

In practical terms, the solubility of 2-methyl-8-nitro-quinoline is instrumental for its reactivity and utilization in chemical reactions, as it allows for enhanced interactions with other molecules. As summarized below:

  1. Insoluble in water
  2. Soluble in organic solvents
  3. Increased solubility with temperature rise

This solubility profile highlights the importance of solvent choice in processes involving 2-methyl-8-nitro-quinoline, ultimately affecting its efficacy and performance in chemical applications.

Interesting facts

Interesting Facts About 2-Methyl-8-nitro-quinoline

2-Methyl-8-nitro-quinoline is a fascinating organic compound that belongs to the quinoline family, known for its vivid array of applications in chemistry and biochemistry. Here are some engaging facts about this compound:

  • Structural Diversity: Quinoline derivatives, including 2-methyl-8-nitro-quinoline, are characterized by their unique bicyclic structure, which consists of a benzene ring fused to a pyridine ring. This structural configuration contributes to their varied reactivity.
  • Biological Significance: Compounds such as 2-methyl-8-nitro-quinoline have attracted interest in medicinal chemistry due to their potential antibacterial and antifungal properties. The nitro group is particularly important as it can serve as a bioisostere for specific pharmacophores.
  • Fluorescent Properties: Some quinoline derivatives exhibit strong fluorescence, making them useful in analytical applications. This property allows scientists to trace biochemical pathways and perform complex biological assays with enhanced visibility.
  • Synthetic Pathways: The synthesis of 2-methyl-8-nitro-quinoline often involves the introduction of the nitro group via electrophilic aromatic substitution. Understanding these synthetic methodologies is crucial for chemists aiming to develop novel compounds.
  • Research and Innovation: The ongoing research in the field of *organic electronics* and *material science* often utilizes quinoline derivatives. Their ability to serve as semiconductors opens a range of possibilities in the development of advanced materials, including organic solar cells.

With such versatile applications and interesting properties, 2-methyl-8-nitro-quinoline continues to be a subject of great interest in both academic and industrial chemistry. As scientists and students delve deeper into its functionalities, they uncover new pathways for innovation and discovery in various fields.

Synonyms
2-Methyl-8-nitroquinoline
8-Nitroquinaldine
QUINALDINE, 8-NITRO-
Quinoline, 2-methyl-8-nitro-
UNII-XRV949AUQZ
XRV949AUQZ
EINECS 212-919-6
NSC 163380
BRN 0145077
NSC-163380
NITROQUINALDINE, 8-
UHPGVDHXHDPYQP-UHFFFAOYSA-
DTXSID30236815
8-NITRO-2-METHYLQUINOLINE
5-20-07-00387 (Beilstein Handbook Reference)
DTXCID60159306
Quinoline, 2-methyl-8-nitro-(9CI)
212-919-6
inchi=1/c10h8n2o2/c1-7-5-6-8-3-2-4-9(12(13)14)10(8)11-7/h2-6h,1h3
uhpgvdhxhdpyqp-uhfffaoysa-n
881-07-2
MFCD00006764
MLS002920759
NSC163380
2-Methyl-8-nitro-quinoline
Oprea1_600646
SCHEMBL230859
CHEMBL167800
BBL010511
STK720136
AKOS000281792
AKOS015897206
CS-W016816
SB67479
SMR001798345
SY077953
VS-02535
DB-021368
EU-0034287
N0539
NS00039240
H11359
SR-01000395953
SR-01000395953-1
Q27293971
Z56862724
F0037-7077