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2-methyl-9-phenyl-2,3,4,9-tetrahydro-1H-indeno[2,1-c]pyridin-2-ium chloride

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Identification
Molecular formula
C19H19ClN
CAS number
56-12-2
IUPAC name
2-methyl-9-phenyl-2,3,4,9-tetrahydro-1H-indeno[2,1-c]pyridin-2-ium;chloride
State
State

This compound is typically found in a solid state at room temperature. Its chemical properties define its stability and behavior in various conditions, such as humidity and temperature.

Melting point (Celsius)
180.00
Melting point (Kelvin)
453.15
Boiling point (Celsius)
310.00
Boiling point (Kelvin)
583.15
General information
Molecular weight
319.82g/mol
Molar mass
319.8210g/mol
Density
1.2000g/cm3
Appearence

2-methyl-9-phenyl-2,3,4,9-tetrahydro-1H-indeno[2,1-c]pyridin-2-ium chloride typically appears as a crystalline solid or powder with a white to off-white color. The compound's crystalline nature may vary depending on its synthesis and hydration level.

Comment on solubility

Solubility of 2-methyl-9-phenyl-2,3,4,9-tetrahydro-1H-indeno[2,1-c]pyridin-2-ium;chloride

The solubility of 2-methyl-9-phenyl-2,3,4,9-tetrahydro-1H-indeno[2,1-c]pyridin-2-ium chloride can be influenced by several factors, particularly its structural complexity and the presence of functional groups. In general, ionic compounds like chlorides tend to have varying solubility profiles in aqueous solutions. The presence of the chloride ion typically indicates better solubility due to its ability to interact favorably with water molecules. Here are some considerations regarding its solubility:

  • Polarity: The quaternary nitrogen in the structure contributes to the molecule's overall polarity, which may enhance its solubility in polar solvents like water.
  • Hydrogen Bonding: Any ability to form hydrogen bonds with water can significantly increase solubility.
  • Temperature Dependency: As with many compounds, solubility may increase with temperature; thus, higher temperatures could result in a greater dissolution rate.
  • Solvent Compatibility: Besides water, the compound may also display solubility in polar organic solvents such as ethanol or methanol, but this can be highly dependent on the specific conditions.

Despite these insights, it’s essential to note that precise solubility values can only be determined experimentally, and can vary with purity and other environmental factors. As always, consulting specific solubility data or conducting solubility tests is crucial for practical applications.

Interesting facts

Interesting Facts about 2-methyl-9-phenyl-2,3,4,9-tetrahydro-1H-indeno[2,1-c]pyridin-2-ium;chloride

This fascinating compound, with its intricate structure, belongs to the class of ionic compounds, offering unique properties that make it a subject of interest in both organic chemistry and medicinal chemistry. Here are some noteworthy points:

  • Diverse Applications: The compound is notable for its potential applications in medicinal chemistry, particularly as a precursor for pharmaceutical compounds. Its unique structure allows for modifications that can lead to bioactive derivatives.
  • Structurally Rich: The bicyclic structure combining indeno and pyridine moieties inherently enhances its electronic properties, making it a compelling model for studies on aromaticity and molecular stability.
  • Research Potential: Recent studies have highlighted its relevance in investigating significant biological activities. Compounds like this could exhibit interesting interactions with biological targets, making them candidates for drug development.
  • Chloride Ion Role: The presence of the chloride ion not only contributes to solubility in various solvents but also plays a critical role in stabilizing the positive charge of the pyridinium ring, enhancing the compound's reactivity.

The complexity of 2-methyl-9-phenyl-2,3,4,9-tetrahydro-1H-indeno[2,1-c]pyridin-2-ium;chloride also opens avenues for extensive computational studies, helping chemists predict its behavior and interactions under various conditions. As we delve into this compound, the interplay of its structural features and potential applications continues to intrigue researchers and students alike.

Synonyms
Phenindamine hydrochloride
Thephorin hydrochloride
5503-08-2
NU 1504 hydrochloride
2-Methyl-9-phenyl-2,3,4,9-tetrahydro-1-pyridindene hydrochloride
UNII-2B049A11FH
2B049A11FH
2,3,4,9-Tetrahydro-2-methyl-9-phenyl-1H-indeno(2,1-c)pyridine hydrochloride
1H-INDENO(2,1-c)PYRIDINE, 2,3,4,9-TETRAHYDRO-2-METHYL-9-PHENYL-, HYDROCHLORIDE
PHENINDAMINE HYDROCHLORIDE [MI]
1H-INDENO(2,1-C)PYRIDINE, 2,3,4,9-TETRAHYDRO-2-METHYL-9-PHENYL-, HYDROCHLORIDE (1:1)
2-methyl-9-phenyl-2,3,4,9-tetrahydro-1H-indeno[2,1-c]pyridin-2-ium;chloride