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DL-threo-β-Methylaspartic acid

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Identification
Molecular formula
C5H9NO4
CAS number
767-67-9
IUPAC name
2-(methylamino)butanedioic acid
State
State

At room temperature, DL-threo-β-Methylaspartic acid is typically in a solid state. This structure is stable under standard conditions of temperature and pressure.

Melting point (Celsius)
220.00
Melting point (Kelvin)
493.00
Boiling point (Celsius)
390.00
Boiling point (Kelvin)
663.00
General information
Molecular weight
147.13g/mol
Molar mass
147.1300g/mol
Density
1.4970g/cm3
Appearence

DL-threo-β-Methylaspartic acid appears as a white crystalline powder. It is generally odorless and is commonly presented in solid form for laboratory uses.

Comment on solubility

Solubility of 2-(Methylamino)butanedioic Acid (C5H9NO4)

2-(Methylamino)butanedioic acid, commonly known as a derivative of aspartic acid, possesses notable solubility characteristics:

  • Water Solubility: This compound is typically highly soluble in water, a property attributed to its polar amino group and the presence of two carboxylic acid functional groups.
  • Solvent Interaction: In addition to water, it exhibits moderate solubility in various organic solvents, especially polar aprotic solvents.
  • pH Dependence: The solubility of 2-(methylamino)butanedioic acid can vary depending on the pH of the solution. It is essentially more soluble at higher pH levels due to the deprotonation of its carboxyl groups.

These factors play a crucial role in its use in chemical reactions and biological systems. Understanding the solubility can help in tailoring effective formulations and enhancing bioavailability in pharmaceutical applications.


Interesting facts

Interesting Facts about 2-(Methylamino)butanedioic Acid

2-(Methylamino)butanedioic acid, often referred to in scientific contexts for its various roles in biochemical pathways, is a fascinating compound that showcases the intersection of organic chemistry and biochemistry. Here are some intriguing points about this compound:

  • Biological Significance: This compound plays a crucial role as an intermediate in amino acid metabolism. As a derivative of aspartic acid, it participates in the synthesis of proteins, which are essential for cellular structure and function.
  • Potential Therapeutic Use: Research has suggested that derivatives of 2-(methylamino)butanedioic acid might exhibit neuroprotective and metabolic benefits, hinting at its potential applications in treating various health conditions.
  • Presence in Nature: Several non-essential amino acids, to which 2-(methylamino)butanedioic acid is closely related, are naturally synthesized within organisms, underlining the compound's importance in sustaining life processes.
  • Structural Unique Characteristics: The presence of a methylamino group contributes to its chemical reactivity, allowing it to form various derivatives that may have distinct biological properties.
  • Chemical Interactions: This compound can interact with different biological molecules, influencing enzyme activities and metabolic pathways, which makes it an interesting subject for further study in metabolic engineering.

In summary, 2-(methylamino)butanedioic acid is not only a product of basic metabolic processes but also a promising candidate for therapeutic applications. Its structural features and reactivity offer a rich area for scientific exploration, and its significance in biochemistry continues to unravel exciting possibilities for future research.

Synonyms
N-Methyl-DL-aspartic acid
17833-53-3
2-(methylamino)butanedioic acid
2-(Methylamino)succinic acid
N-methylaspartic acid
EU52DFC4WJ
N-Methyl-l-aspartic acid HCl
CHEMBL275325
DTXSID20859971
N-Me-Asp-OH
n-methyl-dl-aspartate
DL-Aspartic acid, N-methyl-
N-Me-DL-Asp-OH
UNII-EU52DFC4WJ
DL-2-METHYLAMINOSUCCINIC ACID
MFCD00065918
H-D-MeAsp-OH
Aspartic acid,N-methyl-
N-METHYL-L-ASPARTIC ACID HYDROCHLORIDE
SCHEMBL167682
DL-N-METHYLASPARTIC ACID
DTXCID30209721
CHEBI:181378
METHYL ASPARTIC ACID, DL-
HMS3266A05
HMS3370L14
HMS3411A03
HMS3652P20
HMS3675A03
BCP21209
NSC16206
BDBM50002343
STK246904
(R,S)-2-(Methylamino)succinic acid
AKOS005066589
CS-W018216
FM16185
HY-W017500
NMA;(+)-2-(Methylamino)succinic acid
NCGC00015666-02
NCGC00015666-03
NCGC00015666-04
NCGC00095062-01
NCGC00095062-02
AC-24120
BP-12733
DS-14547
SY035118
DB-044327
DB-054563
2-(Methylamino)succinic acid (Me-DL-Asp-OH)
G73908
AB01326367-02
EN300-6958635
BRD-A02508087-001-01-1
BRD-A02508087-001-02-9
Q27277365
964-924-4