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2-Methylbenzamide

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Identification
Molecular formula
C8H9NO
CAS number
609-96-1
IUPAC name
2-methylbenzamide
State
State

At room temperature, 2-Methylbenzamide is in a crystalline solid state.

Melting point (Celsius)
111.00
Melting point (Kelvin)
384.15
Boiling point (Celsius)
312.00
Boiling point (Kelvin)
585.15
General information
Molecular weight
135.17g/mol
Molar mass
135.1660g/mol
Density
1.0700g/cm3
Appearence

2-Methylbenzamide appears as a solid crystalline substance. It is typically white to off-white in color.

Comment on solubility

Solubility of 2-methylbenzamide

2-methylbenzamide (C9H11NO) demonstrates some intriguing characteristics with respect to its solubility. This compound, part of the amide family, exhibits varying solubility in different solvents:

  • Polar Solvents: 2-methylbenzamide shows a significant solubility in polar solvents due to its ability to engage in hydrogen bonding. The presence of the carbonyl group (C=O) enhances its interactions with other polar molecules.
  • Nonpolar Solvents: In nonpolar solvents, the solubility is much lower. The hydrophobic character of the aromatic ring limits its affinity for such solvents, making it less soluble.

In general, temperature also plays a crucial role in the solubility of 2-methylbenzamide. As the temperature increases, the solubility tends to improve, allowing for increased interactions of the solute molecules with the solvent.

Overall, to summarize:

  1. Solubility is high in polar solvents.
  2. Solubility is low in nonpolar solvents.
  3. Increased temperature contributes to higher solubility.

Thus, understanding the solubility characteristics of 2-methylbenzamide is vital for its applications in various chemical processes and formulations.

Interesting facts

Interesting Facts About 2-Methylbenzamide

2-Methylbenzamide, an aromatic amide derivative, is a fascinating compound with numerous applications and properties that intrigue both chemists and chemical engineers. Here are some noteworthy points:

  • Structural Characteristics: The structure of 2-methylbenzamide features a benzene ring substituted with a methyl group and an amide functional group, influencing both its reactivity and physical properties. This substitution pattern allows for unique interactions in reactions involving aromatic compounds.
  • Role in Synthesis: This compound serves as a key intermediate in organic synthesis, especially in the preparation of pharmaceuticals. It is often used in the synthesis of various biologically active molecules, showcasing how modifications of simple amides can lead to complex structures.
  • Biological Significance: Some derivatives of benzamide compounds are known to exhibit biological activity, including anti-inflammatory and analgesic properties. Researchers are continually investigating the potential of 2-methylbenzamide and its derivatives in medicinal chemistry.
  • Physical Properties: While specific physical data are excluded, the presence of an amide group typically imparts notable characteristics such as hydrogen bonding capability, affecting the compound's boiling and melting points and making it relevant in various chemical processes.
  • Environmental Considerations: Understanding the environmental fate of amides like 2-methylbenzamide is crucial, as such compounds can participate in various biological and chemical processes, influencing ecosystem health.

As stated by renowned chemist Marie Curie, “One never notices what has been done; one can only see what remains to be done.” The study and application of 2-methylbenzamide exemplify ongoing efforts in the field of organic chemistry, proving that even small modifications to chemical structures can lead to significant advancements in science and medicine.

In conclusion, 2-methylbenzamide stands as a testament to the beauty and complexity of organic compounds, inspiring continued research and innovation.

Synonyms
2-METHYLBENZAMIDE
o-Toluamide
Benzamide, 2-methyl-
o-Tolylamide
Toluenemonoamine
2-Toluamide
CCRIS 4669
ortho-toluamide
NSC 2169
EINECS 208-427-6
UNII-13WGF92B0H
DTXSID6025569
NSC-2169
O-TOLUAMIDE [MI]
METHYLBENZAMIDE, 2-
DTXCID905569
orthoToluamide
oTolylamide
oMethylbenzamide
oToluic amide
2Methylbenzamide
2Toluamide
Benzamide, 2methyl
208-427-6
xxunigzdnwwyed-uhfffaoysa-n
527-85-5
o-Toluic amide
o-Methylbenzamide
2-BroMo-4-fluoro-
toluamide
1262396-02-0
2-methyl-benzamide
MFCD00007982
13WGF92B0H
methyl benzamide
NSC2169
2-Methylbenzamide, 98%
SCHEMBL6099
MLS002302989
CHEMBL1489405
HMS3039P12
Tox21_200187
STL283913
AKOS003409186
FM71127
NCGC00091639-01
NCGC00091639-02
NCGC00257741-01
AS-56927
CAS-527-85-5
SMR001307306
SY113886
DB-052186
CS-0006713
NS00032584
D97423
AE-508/40403814
Q27251545
F1084-0675