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2-Methylindoline

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Identification
Molecular formula
C9H11N
CAS number
13198-42-6
IUPAC name
2-methylindoline
State
State

At room temperature, 2-Methylindoline exists as a liquid.

Melting point (Celsius)
-30.00
Melting point (Kelvin)
243.15
Boiling point (Celsius)
222.00
Boiling point (Kelvin)
495.15
General information
Molecular weight
133.19g/mol
Molar mass
133.1920g/mol
Density
1.0270g/cm3
Appearence

2-Methylindoline is a colorless to pale yellow liquid. It has a characteristic amine-like odor.

Comment on solubility

Solubility of 2-methylindoline

2-methylindoline, with a molecular formula of C10H9N, exhibits interesting solubility characteristics that are important for its applications in various fields. Understanding its solubility can provide insights into its behavior in different environments.

Solubility Characteristics

The solubility of 2-methylindoline can be summarized as follows:

  • Solvent Interaction: This compound is known to be soluble in organic solvents such as ethanol, dimethyl sulfoxide (DMSO), and chloroform.
  • Water Solubility: 2-methylindoline exhibits limited solubility in water, which is common for many organic compounds containing aromatic structures.
  • Influence of Temperature: As with many organic compounds, its solubility may increase with rising temperatures, making it more dissolvable in hot solvents.

In practice, this means that 2-methylindoline can be readily utilized in organic synthesis and chemical reactions where non-polar or weakly polar solvents are employed. The limited water solubility should be noted for applications in aqueous systems to avoid precipitation or reduced reactivity.

Key Considerations

When working with 2-methylindoline, consider the following:

  • Always evaluate the choice of solvent based on the desired reaction environment.
  • Be cautious of temperature effects on solubility, especially in reactions where heat is applied.
  • Understand the potential implications of solubility on the compound's stability and efficacy in formulations.

In summary, the solubility of 2-methylindoline is a vital aspect to consider for its effective use in various chemical applications. Its behavior in different solvents can significantly influence experimental outcomes and product development.

Interesting facts

Interesting Facts About 2-Methylindoline

2-Methylindoline is a fascinating compound that belongs to the family of indolines, known for their unique bicyclic structure and aromatic properties. Here are some remarkable insights about this intriguing compound:

  • Chemical Structure: The molecule features a methyl group attached to the indoline framework, which contributes to its unique properties and reactivity. This structural modification can significantly influence its chemical behavior.
  • Biological Significance: Indoline derivatives, including 2-methylindoline, are of interest in medicinal chemistry. They exhibit potential biological activities, making them valuable in the search for new pharmaceuticals. Some derivatives have shown antitumor and antimicrobial properties.
  • Synthesis: The synthesis of 2-methylindoline can involve various methods, including the reduction of ketones or using an indole precursor. The reaction conditions can be fine-tuned to maximize yield and purity, showcasing the versatility of organic synthesis techniques.
  • Applications: In addition to its potential in medicine, 2-methylindoline finds applications in organic materials, dyes, and as a building block in the development of complex organic molecules.
  • Research Interest: Ongoing studies in the field of organic synthesis aim to explore new catalytic methods for its formation, enhancing efficiency, and minimizing waste, reflecting the modern push towards green chemistry.

The allure of 2-methylindoline lies not only in its potential applications but also in the ongoing research that seeks to unlock the full range of its capabilities. As scientists continue to explore the chemistry of this compound, who knows what innovative uses might emerge in the future?

Synonyms
2-Methylindoline
6872-06-6
2-methyl-2,3-dihydro-1H-indole
2,3-Dihydro-2-methylindole
1H-Indole, 2,3-dihydro-2-methyl-
2-Methyl-2,3-dihydroindole
Indoline, 2-methyl-
Dihydroindole, 2-methyl-
alpha-Methyldihydroindole
2,3-DIHYDRO-2-METHYL-1H-INDOLE
5GAL2SM4VV
PE-11
NSC 65598
EINECS 229-971-0
NSC-65598
BRN 0081505
DTXSID70884339
5-20-06-00344 (Beilstein Handbook Reference)
DTXCID90835247
229-971-0
MFCD00005706
.alpha.-Methyldihydroindole
2-methyl indoline
MFCD19217263
2-methyl-indoline
NSC65598
a-Methyldihydroindole
UNII-5GAL2SM4VV
2-Methylindoline, 98%
NCIOpen2_000227
SCHEMBL33268
SCHEMBL12837999
1H-Indole,3-dihydro-2-methyl-
CHEBI:166548
STR07895
STL124108
AKOS000119057
AKOS016356737
CS-W013390
PS-3274
SB15111
SB15112
SB15113
AC-28908
SY014921
SY099486
DB-021388
M0871
NS00045719
EN300-19044
D71186
Q27262116
F2190-0414
Z104472410
InChI=1/C9H11N/c1-7-6-8-4-2-3-5-9(8)10-7/h2-5,7,10H,6H2,1H