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Phthalimide

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Identification
Molecular formula
C8H7NO2
CAS number
85-41-6
IUPAC name
2-methylisoindoline-1,3-dione
State
State

At room temperature, Phthalimide is in a solid state. It typically manifests as crystalline powder, which is characteristic of many organic compounds with similar structure.

Melting point (Celsius)
238.00
Melting point (Kelvin)
511.15
Boiling point (Celsius)
336.00
Boiling point (Kelvin)
609.15
General information
Molecular weight
147.13g/mol
Molar mass
147.1310g/mol
Density
1.2990g/cm3
Appearence

Phthalimide appears as a colorless to white crystalline compound. It often forms monoclinic crystals that may appear as a powder. The compound is known for its solid, crystalline nature at room temperature.

Comment on solubility

Solubility of 2-methylisoindoline-1,3-dione

2-methylisoindoline-1,3-dione, also referred to as methyl isoindoline dione, exhibits specific solubility characteristics that are important for its applications in various fields. Understanding its solubility can provide insights into its behavior in different environments and formulations.

General Solubility Profile

This compound is generally known to be:

  • Soluble in organic solvents: 2-methylisoindoline-1,3-dione dissolves well in solvents such as dimethyl sulfoxide (DMSO), acetone, and ethyl acetate.
  • Poorly soluble in water: Its polar characteristics limit its ability to dissolve in aqueous solutions, which can be a crucial factor depending on the intended use.

Factors Affecting Solubility

The solubility of 2-methylisoindoline-1,3-dione can be influenced by several factors:

  • Temperature: Increased temperature often enhances solubility in organic solvents.
  • pH Levels: Changing the acidity or alkalinity of a solution may affect the ionization and thus the solubility.
  • Polarity of Solvent: Utilization of polar versus non-polar solvents can significantly impact solubility outcomes.

In summary, while 2-methylisoindoline-1,3-dione demonstrates good solubility in organic solvents, its limited water solubility highlights the importance of selecting suitable solvents for its applications. As the saying goes, “like dissolves like,” which emphasizes the significance of matching solvent properties to the solubility characteristics of the compound in question.

Interesting facts

Exploring 2-methylisoindoline-1,3-dione

2-methylisoindoline-1,3-dione is a noteworthy compound in the field of organic chemistry. This compound is intriguing for several reasons:

  • Structural Diversity: The unique isoindoline structure plays a vital role in the compound's reactivity and potential applications.
  • Pharmaceutical Relevance: Compounds with similar structures have been studied for their biological activities, including anti-cancer and anti-inflammatory properties. This hints at the possibility of 2-methylisoindoline-1,3-dione serving as a useful scaffold for drug development.
  • Synthetic Accessibility: The synthesis of this compound often involves cyclic reactions and can serve as an excellent laboratory exercise for students learning about synthetic organic chemistry.
  • Research Potential: Ongoing research in material science has indicated that isoindoline derivatives may possess interesting electronic properties, making them candidates for advanced materials.

As you dive deeper into studying 2-methylisoindoline-1,3-dione, consider the compound’s **multi-faceted nature** and the potential it holds for further exploration and application across various fields, including medicine and materials science. Just as chemist Robert H. Grubbs once stated, “Chemistry is the central science.” Indeed, compounds like 2-methylisoindoline-1,3-dione illustrate the pivotal role intricate structures play in our understanding of both the molecular world and practical applications.

Overall, this compound exemplifies the **beauty and complexity** of organic chemistry, inviting curiosity and further inquiry into its myriad potential uses and benefits.

Synonyms
N-Methylphthalimide
550-44-7
Phthalimide, N-methyl-
1H-Isoindole-1,3(2H)-dione, 2-methyl-
N-methyl phthalimide
2-methyl-isoindole-1,3-dione
EINECS 208-982-4
NSC 44059
BRN 0124428
DTXSID5027198
AI3-01393
647UP45J2U
NSC-44059
DTXCID807198
5-21-10-00273 (Beilstein Handbook Reference)
208-982-4
2-Methylisoindoline-1,3-dione
2-methylisoindole-1,3-dione
2-METHYL-1H-ISOINDOLE-1,3(2H)-DIONE
MFCD00023063
NCGC00164164-02
UNII-647UP45J2U
N-Nethylphthalimide
NSC44059
N-Methylphthalimide, 98%
SCHEMBL28263
1H-Isoindole-1, 2-methyl-
CHEMBL172614
Tox21_400053
STL483065
AKOS002384372
CS-W016139
SB64121
NCGC00164164-01
NCGC00164164-03
CAS-550-44-7
SY017788
2-Methyl-1H-isoindole-1,3(2H)-dione #
DB-050520
M0299
NS00022360
D71133
AE-848/00900046
Q27263715