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2-Methylpiperidine

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Identification
Molecular formula
C6H13N
CAS number
109-05-7
IUPAC name
2-methylpiperidine
State
State

At room temperature, 2-Methylpiperidine is in a liquid state due to its relatively low melting point and moderate boiling point.

Melting point (Celsius)
-17.10
Melting point (Kelvin)
256.00
Boiling point (Celsius)
117.40
Boiling point (Kelvin)
390.60
General information
Molecular weight
99.18g/mol
Molar mass
99.1760g/mol
Density
0.8572g/cm3
Appearence

2-Methylpiperidine is a clear, colorless liquid. It possesses a strong amine-like odor typical of piperidine derivatives.

Comment on solubility

Solubility of 2-methylpiperidine

2-methylpiperidine, with the chemical formula C7H15N, is a cyclic amine that exhibits interesting solubility characteristics. Its solubility can be influenced by several factors, primarily due to its polar nitrogen atom and hydrocarbon backbone.

General Solubility Characteristics

In general, 2-methylpiperidine is soluble in water, although it may not be highly soluble compared to other small amines. Here’s a breakdown of its solubility behavior:

  • Water: Exhibits moderate solubility due to hydrogen bonding capabilities.
  • Organic Solvents: Readily soluble in organic solvents like ethanol, methanol, and ether, owing to its hydrophobic hydrocarbon structure.

Factors Affecting Solubility

The solubility of 2-methylpiperidine can be affected by:

  • Temperature: Higher temperatures tend to increase solubility.
  • Concentration of solvents: Solvent polarity plays a crucial role.
  • Presence of other solutes: The solubility may be influenced by interactions with other chemicals in a mixture.

As a rule of thumb, compounds with both polar and non-polar characteristics can better dissolve in a range of solvents, making 2-methylpiperidine quite versatile in different chemical environments. Therefore, understanding the solubility of such compounds is paramount for their application in various chemical processes.

Interesting facts

Interesting Facts about 2-methylpiperidine

2-methylpiperidine is a fascinating compound in the realm of organic chemistry, particularly due to its unique structure and applications. Here are some key points that highlight its significance:

  • Structural Characteristics: This compound features a piperidine ring with a methyl group attached at the second position, contributing to its diverse chemical properties.
  • Chemical Reactivity: The introduction of the methyl group enhances the nucleophilicity of the nitrogen atom, making 2-methylpiperidine an important intermediate in various reactions.
  • Application in Synthesis: It is frequently utilized in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds, proving vital in medicinal chemistry.
  • Biological Activity: Research indicates that 2-methylpiperidine derivatives may exhibit interesting biological properties, such as being potential inhibitors for certain enzymes.

As an aspiring chemist, one might find it intriguing to explore how variations in structure impact reactivity and the subsequent applications in real-world scenarios. The compound serves as a reminder of the intricacies of organic molecules and their profound influence across various industries.

In the words of renowned chemist Linus Pauling, "Chemistry is the study of matter, but I prefer to view it as the study of change." 2-methylpiperidine perfectly embodies this notion as it transforms through reactions to create compounds that can have significant implications in science and industry.

Synonyms
2-METHYLPIPERIDINE
109-05-7
2-Pipecoline
Piperidine, 2-methyl-
Pipicoline
alpha-Pipecoline
alpha-Pipecolin
2-Methyl-piperidine
PIPECOLINE, ALPHA
alpha-Methylpiperidine
.alpha.-Methylpiperidine
.alpha.-Pipecolin
EINECS 203-642-1
D-alpha-Pipecoline
NSC 31047
.alpha.-Pipecoline
BRN 0079804
Pipecoline, .alpha.
2-Pipecoline (8CI)
UNII-22E509663B
NSC-31047
2-Methyl hexahydropyridine
(+/-)-2-methylpiperidine
DL-2-METHYLPIPERIDINE
22E509663B
FEMA NO. 4244
DTXSID90861728
2-METHYLPIPERIDINE [FHFI]
5-20-04-00071 (Beilstein Handbook Reference)
(+/-)-.ALPHA.-PIPECOLINE
2-Methylpiperidine, 98%
WLN: T6MTJ B1
2-methyl piperidine
a-Pipecoline
alpha -pipecolin
alpha -pipecoline
2-methylpyperidine
alpha -methylpiperidine
rac.-2-methylpiperidine
(RS) 2-(methyl)piperidine
(+/-)-2-Methyl-piperidine
CHEMBL21454
NSC462
(+/-)-ALPHA-PIPECOLINE
DTXCID30810614
NSC-462
CHEBI:186840
2-Pipecoline ; 2-Methylpiperidine
NSC31047
STR03043
MFCD00005982
STL183272
AKOS000120096
AKOS016039384
SB44667
SB44682
NS00041435
P0443
EN300-20696
F93019
Q27253646
F2190-0326
Z104479894
203-642-1