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8-Hydroxyquinaldine

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Identification
Molecular formula
C10H9NO
CAS number
611-36-9
IUPAC name
2-methylquinolin-8-ol
State
State
Solid at room temperature, typically presented in powder or crystalline form.
Melting point (Celsius)
75.00
Melting point (Kelvin)
348.00
Boiling point (Celsius)
354.00
Boiling point (Kelvin)
627.00
General information
Molecular weight
159.19g/mol
Molar mass
159.1920g/mol
Density
1.2480g/cm3
Appearence

8-Hydroxyquinaldine appears as a yellow to tan crystalline solid. It has a distinct appearance that may include a slightly granular texture, and it is moderately soluble in common organic solvents such as ethanol and chloroform.

Comment on solubility

Solubility of 2-methylquinolin-8-ol

The solubility of 2-methylquinolin-8-ol, a compound recognized for its unique structure and applications, can be influenced by various factors. Understanding its solubility is crucial for both practical uses and theoretical studies.

  • Polar vs. Nonpolar Solvents: This compound exhibits greater solubility in polar organic solvents such as ethanol and methanol due to the presence of hydroxyl groups that can engage in hydrogen bonding.
  • pH Sensitivity: The solubility can significantly change with pH levels. In acidic conditions, the hydroxyl group may become protonated, altering its solubility profile.
  • Temperature Dependence: Like many organic compounds, solubility generally increases with temperature; hence, elevated temperatures might enhance the dissolution of 2-methylquinolin-8-ol in solvents.

In summary, while 2-methylquinolin-8-ol is soluble in certain polar solvents, its solubility is intricately linked to external conditions such as solvent polarity, pH, and temperature. As a researcher or enthusiast, it is important to consider these factors when working with this compound to optimize its use in various applications.

Interesting facts

Exploring 2-Methylquinolin-8-ol

2-Methylquinolin-8-ol is a fascinating compound that belongs to the quinoline family, which is known for its diverse applications in various fields of science and technology. This compound is particularly notable for several reasons:

  • Biological Activity: 2-Methylquinolin-8-ol exhibits significant biological properties, including antimicrobial and antifungal activities. Such properties make it a subject of interest in medicinal chemistry and pharmaceutical research.
  • Fluorescent Properties: Due to its specific chemical structure, this compound demonstrates interesting photophysical properties. It can act as a fluorescent probe in biological imaging, allowing scientists to visualize cellular processes in real time.
  • Synthetic Versatility: The synthesis of 2-methylquinolin-8-ol can be achieved through various methods, making it a versatile compound in organic synthesis. This versatility aids in modifying its structure to enhance desired properties for specific applications.
  • Complex Formation: This compound has the ability to form complexes with metal ions, including transition metals. Such complexes are valuable in catalysis and have potential applications in materials science.

As a member of the quinoline family, 2-methylquinolin-8-ol shares many characteristics with other derivatives, yet its unique features and applications make it stand out. As one researcher noted, "The study of compounds like 2-methylquinolin-8-ol not only expands our understanding of chemical interactions but also our ability to innovate in drug development and materials science."

Overall, 2-methylquinolin-8-ol serves as an excellent example of how a seemingly simple compound can participate in complex interactions and applications across various scientific disciplines.

Synonyms
8-Hydroxyquinaldine
2-Methylquinolin-8-ol
826-81-3
2-Methyl-8-quinolinol
2-Methyl-8-hydroxyquinoline
8-HYDROXY-2-METHYLQUINOLINE
8-Quinolinol, 2-methyl-
2-Methyloxine
Hydroxyquinaldine
8-Hydroxyqinaldine
EINECS 212-562-6
NSC 58553
BRN 0119194
NSC-58553
7W631H5302
DTXSID3061184
EC 212-562-6
5-21-03-00341 (Beilstein Handbook Reference)
HYDROXY-2-METHYLQUINOLINE, 8-
NSC-403349
2Methyloxine
8hydroxyquinaldine
2Methyl8quinolinol
2Methylquinolin8ol
8Quinolinol, 2methyl
2Methyl8hydroxyquinoline
8-H-2-MQ cpd
DTXCID3048312
inchi=1/c10h9no/c1-7-5-6-8-3-2-4-9(12)10(8)11-7/h2-6,12h,1h
2-Methyl-quinolin-8-ol
MFCD00006765
CHEMBL316892
8-Hydroxyquinaldine (8-Hydroxy-2-methylquinoline)
2-Methyl 8-quinolinol
2-methyl 8-quinolonol
8-Hydroxyquinaldine; 8-Hydroxy-2-methylquinoline
2-Methyl-oxine
UNII-7W631H5302
8-hydroxy-quinaldine
8-HYDROXY QUINALDINE
SCHEMBL297247
2-Methyl-8-quinolinol, 98%
quinoline, 8-hydroxy-2-methyl-
CHEBI:180510
HMS1647N13
NSC58553
BDBM50065785
STK037617
AKOS000121472
CS-W004053
FS-2928
SB67453
NCGC00188188-01
AC-12780
DB-056646
M0420
NS00007994
EN300-17635
P20524
AB-016/30038017
Q27268939
Z56969328
F0001-2119