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2-Mercaptobenzimidazole

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Identification
Molecular formula
C7H6N2S
CAS number
583-39-1
IUPAC name
2-methylsulfanyl-1H-benzimidazole
State
State

At room temperature, 2-Mercaptobenzimidazole is typically in a solid state, existing as a crystalline powder.

Melting point (Celsius)
304.00
Melting point (Kelvin)
577.15
Boiling point (Celsius)
410.00
Boiling point (Kelvin)
683.15
General information
Molecular weight
150.21g/mol
Molar mass
150.2100g/mol
Density
1.4200g/cm3
Appearence

2-Mercaptobenzimidazole appears as a pale yellow to off-white crystalline powder. It is used in various industrial applications, primarily as a stabilizer in rubber manufacturing.

Comment on solubility

Solubility of 2-methylsulfanyl-1H-benzimidazole

The compound 2-methylsulfanyl-1H-benzimidazole presents a fascinating case regarding its solubility properties. Understanding its solubility is crucial for various applications, especially in pharmaceuticals and agrochemicals. Here's what we need to know:

  • Solubility in Water: This compound is typically sparingly soluble in water, which can limit its bioavailability and effectiveness in aqueous environments.
  • Solubility in Organic Solvents: On the other hand, it exhibits better solubility in organic solvents such as ethanol and DMSO, making it more accessible for certain chemical reactions and formulations.
  • Temperature Effect: Increasing the temperature generally enhances its solubility in both types of solvents, though the increase may vary.

As a rule of thumb, like dissolves like, meaning that polar solvents will be more effective for polar substances, while non-polar solvents will suit non-polar compounds. This property emphasizes the importance of selecting the right solvent for applications involving 2-methylsulfanyl-1H-benzimidazole.

In summary, when working with this compound, consider the solvent choice carefully to optimize solubility and ensure effective usage in various chemical processes.

Interesting facts

Interesting Facts about 2-methylsulfanyl-1H-benzimidazole

2-methylsulfanyl-1H-benzimidazole is a fascinating compound that has drawn attention in various fields, particularly in medicinal chemistry and pharmacology. Here are some intriguing points about this compound:

  • Structural Insights: The compound features a benzimidazole core, which is a fused bicyclic structure containing both benzene and imidazole rings. This unique architecture contributes to its interesting chemical reactivity and biological activity.
  • Sulfur Atom: The presence of a methylsulfanyl (-S-CH3) group adds intriguing properties to the compound, influencing its reactivity and solubility, and often enhancing its biological profile.
  • Biological Significance: Compounds related to benzimidazoles, including 2-methylsulfanyl-1H-benzimidazole, have shown promise in medicinal applications. They are often investigated for their potential as *antimicrobial agents*, *antiparasitic drugs*, and even *anticancer therapeutics*.
  • Research Interest: Scientists are continuously exploring derivatives of benzimidazoles to optimize their pharmacological properties. This compound serves as a potential lead compound, paving the way for the design of novel therapeutics.
  • Environmental and Material Sciences: Beyond its biological applications, 2-methylsulfanyl-1H-benzimidazole can also play a role in material sciences, such as in the synthesis of novel polymers or as a component in organic electronics.

In conclusion, the study of 2-methylsulfanyl-1H-benzimidazole exemplifies the intricate relationship between structure and function in chemistry, showcasing how small modifications can lead to vast differences in activity and application. As quoted by one renowned chemist, "The beauty of chemistry lies in its ability to transform simple elements into complex systems with remarkable properties."

Synonyms
2-(Methylthio)benzimidazole
7152-24-1
2-Methylmercaptobenzimidazole
1H-Benzimidazole, 2-(methylthio)-
2-(Methylsulfanyl)-1H-benzimidazole
S-Methyl-2-mercaptobenzimidazole
Benzimidazole, 2-(methylthio)-
2-Methylthio benzimidazole
BENZIMIDAZOLE, 2-METHYLTHIO-
NSC 21699
EINECS 230-494-5
3O1W4OYE3V
BRN 0122360
2-(Methylmercapto)benzimidazole
NSC-21699
UNII-3O1W4OYE3V
DTXSID2064577
5-23-11-00263 (Beilstein Handbook Reference)
2-(METHYLSULFANYL)BENZIMIDAZOLE
DTXCID4047046
230-494-5
inchi=1/c8h8n2s/c1-11-8-9-6-4-2-3-5-7(6)10-8/h2-5h,1h3,(h,9,10
ockjfohzlxiaat-uhfffaoysa-n
2-(methylthio)-1H-benzo[d]imidazole
2-methylthiobenzimidazole
2-methylsulfanyl-1H-benzimidazole
2-(methylthio)-1H-benzimidazole
2-(methylsulfanyl)-1H-1,3-benzodiazole
MFCD00005594
2-Methylsulfanyl-1H-benzoimidazole
NSC21699
Maybridge1_003491
Maybridge1_006291
2-(methylthio)-benzimidazole
CHEMBL72355
SCHEMBL374735
HMS559F21
WLN: T56 BM DNJ CS1
2-(Methylthio)benzimidazole, 97%
HAA15224
STK394299
AKOS000275364
CCG-102422
AS-62226
DP 01217
SY049473
DB-055542
CS-0150092
M0438
NS00037237
EN300-16095
D83702
AB00981269-01
AF-615/01049027
Z53833331