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2-Methylthiopyridine

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Identification
Molecular formula
C6H7NS
CAS number
694-55-3
IUPAC name
2-methylsulfanylpyridine
State
State

Liquid at room temperature with a relatively low viscosity.

Melting point (Celsius)
-28.50
Melting point (Kelvin)
244.65
Boiling point (Celsius)
188.00
Boiling point (Kelvin)
461.15
General information
Molecular weight
125.19g/mol
Molar mass
125.1910g/mol
Density
1.1054g/cm3
Appearence

2-Methylthiopyridine appears as a clear to pale yellow liquid. It has a characteristic odor typical of sulfur-containing organic compounds.

Comment on solubility

Solubility of 2-methylsulfanylpyridine

2-methylsulfanylpyridine, also known in some contexts as 2-(methylsulfanyl)pyridine, exhibits moderate solubility profiles that are contingent upon several factors, such as temperature and the solvent used. The compound’s polarity plays a significant role in its solubility, which can be summarized as follows:

  • Solvent Interaction: 2-methylsulfanylpyridine tends to dissolve well in polar solvents due to its ability to engage in dipole-dipole interactions. Common solvents include:
    • Water
    • Ethanol
    • Dimethyl sulfoxide (DMSO)
  • Limited Solubility in Non-Polar Solvents: In contrast, its solubility in non-polar solvents is considerably low due to the hydrophobic nature of those solvents.
  • Temperature Dependence: Increasing temperature often enhances the solubility of 2-methylsulfanylpyridine, which is a general characteristic of many organic compounds.

It's important to note that the solubility can vary significantly among different conditions, thus making precise predictions challenging. As a general observation, 2-methylsulfanylpyridine is regarded as a moderately soluble compound, emphasizing the need for tailored experimental approaches when working with it in various chemical environments.

Interesting facts

Interesting Facts about 2-Methylsulfanylpyridine

2-Methylsulfanylpyridine is a fascinating aromatic compound that belongs to the family of pyridines, which are known for their heterocyclic structure. This compound has gained attention in various fields, especially in medicinal and organic chemistry, due to its unique properties and potential applications.

Key Highlights:

  • Structural Characteristics: The presence of the methylsulfanyl group (-SCH3) on the pyridine ring provides interesting reactivity patterns, making it a versatile intermediate in organic synthesis.
  • Biological Activity: Compounds similar to 2-methylsulfanylpyridine have shown promising biological activities, including antimicrobial and anti-inflammatory properties, which could pave the way for new drug development.
  • Solvent Properties: It is often utilized in various solvent applications due to its polar nature, allowing it to dissolve a range of organic compounds effectively.
  • Functionalization Potential: The functional groups present in 2-methylsulfanylpyridine can be easily modified, allowing chemists to explore new pathways for synthesizing more complex molecules.

The compound also presents an interesting case study for those diving into the world of heterocyclic chemistry, illustrating how subtle changes in molecular structure can drastically affect the reactivity and properties of a compound. As one researcher puts it, “Exploring compounds like 2-methylsulfanylpyridine is like uncovering the secrets of nature; the potential is limitless!”

This compound not only enriches our understanding of chemical behaviors but also serves as an inspiration for innovative solutions in pharmaceuticals and materials science.

Synonyms
18438-38-5
2-(Methylthio)pyridine
PYRIDINE, 2-(METHYLTHIO)-
Methyl 2-pyridyl sulfide
2-Pyridyl methyl sulfide
2-Methylthiolpyridine
Methylthio-2 pyridine
Methylthio-2 pyridine [French]
BRN 0108190
DTXSID00171567
5-21-02-00033 (Beilstein Handbook Reference)
DTXCID7094058
623-744-3
InChI=1/C6H7NS/c1-8-6-4-2-3-5-7-6/h2-5H,1H
2-Methylthiopyridine
2-methylsulfanylpyridine
MFCD01691593
2-(Methylsulfanyl)pyridine
2-Methylthio pyridine
methylthiopyridine
2-METHYLMERCAPTO-PYRIDINE
pyridine, 2-methylthio-
2-methylsulfanyl-pyridine
2-(Methylsulfanyl)pyridine #
SCHEMBL354087
SCHEMBL798143
2-METHYLMERCAPTOPYRIDINE
SCHEMBL1036554
SCHEMBL1555607
SCHEMBL2186562
SCHEMBL2562069
SCHEMBL29364925
AKOS006230363
SB52377
AS-40366
SY015557
DB-021401
M1849
2-(Methylthio)pyridine, >=95.0% (HPLC)
AC-907/34117043
Q63395430