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2-(methylsulfonylmethyl)tetrahydrofuran

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Identification
Molecular formula
C6H12O3S
CAS number
57698-35-6
IUPAC name
2-(methylsulfonylmethyl)tetrahydrofuran
State
State

At room temperature, 2-(methylsulfonylmethyl)tetrahydrofuran is a liquid. It is typically used in synthetic applications and is miscible with many organic solvents.

Melting point (Celsius)
-55.00
Melting point (Kelvin)
218.15
Boiling point (Celsius)
120.00
Boiling point (Kelvin)
393.15
General information
Molecular weight
164.22g/mol
Molar mass
164.2210g/mol
Density
1.2330g/cm3
Appearence

2-(Methylsulfonylmethyl)tetrahydrofuran is typically a colorless to pale yellow liquid with a distinctive odorous quality. It is commonly noted for its clarity and lack of suspended particles when pure.

Comment on solubility

Solubility of 2-(methylsulfonylmethyl)tetrahydrofuran

The solubility of 2-(methylsulfonylmethyl)tetrahydrofuran is influenced by its unique chemical structure, particularly the presence of the sulfonyl group. This compound demonstrates a moderate degree of solubility in various solvents. Here are some key points to consider:

  • Polar Solvents: 2-(methylsulfonylmethyl)tetrahydrofuran is generally soluble in polar solvents such as water, due to the ability of its sulfonyl group to engage in hydrogen bonding.
  • Non-Polar Solvents: In non-polar solvents, its solubility may decrease significantly. This is attributed to the relatively non-polar character of the tetrahydrofuran ring compared to the polar sulfonyl group.
  • Temperature Effects: Solubility is often temperature-dependent. Increased temperatures can enhance solubility in both polar and non-polar solvents, allowing for greater dissolution rates.

Overall, the solubility profile of 2-(methylsulfonylmethyl)tetrahydrofuran showcases the fascinating interplay between hydrophobic and hydrophilic characteristics within its molecular framework. As the compound finds its applications, understanding its solubility behavior becomes crucial for effective utilization.

Interesting facts

Interesting Facts about 2-(Methylsulfonylmethyl)tetrahydrofuran

2-(Methylsulfonylmethyl)tetrahydrofuran is a fascinating organic compound that belongs to the family of tetrahydrofuran derivatives. Its unique structure not only contributes to interesting chemical properties but also opens up avenues for various applications in modern chemistry.

Chemical Structure and Properties

The compound features a tetrahydrofuran ring, which is a five-membered, oxygen-containing heterocycle. The addition of a methylsulfonylmethyl group enhances its potential for:

  • Increased reactivity: This makes it valuable in organic synthesis.
  • Solvent properties: The compound can act as a solvent for various chemical reactions.

Applications

2-(Methylsulfonylmethyl)tetrahydrofuran finds its use in multiple domains:

  • Pharmaceutical Development: It is often considered in drug design due to its ability to act as a bioisostere.
  • Polymer Chemistry: The compound serves as a useful building block for synthesizing various polymers.
  • Reaction Medium: Its properties make it ideal for particular reactions and processes in organic chemistry.

Environmental Aspects

This compound is also noted for its *potential low toxicity*, making it a more environmentally friendly option in comparison to traditional solvents and reagents.
Furthermore, ongoing research aims to understand its *biodegradability*, which could help in formulating greener chemical processes.

Quote from Research

An interesting quote from a recent study illustrates its significance: "The incorporation of methylsulfonyl groups into organic frameworks unlocks new reactivity pathways and aligns with the principles of sustainability in chemistry."

In conclusion, 2-(Methylsulfonylmethyl)tetrahydrofuran is a remarkable compound that embodies the intersection of structural properties and practical applications, making it a subject of interest in many scientific fields.

Synonyms
Methyl tetrahydrofurfuryl sulfone
15396-31-3
BRN 1364871
Tetrahydro-2-((methylsulfonyl)methyl)furan
FURAN, TETRAHYDRO-2-((METHYLSULFONYL)METHYL)-
2-(methylsulfonylmethyl)oxolane
Methyl(oxolan-2-ylmethyl) sulfone
SCHEMBL18665525
DTXSID10934882
2-[(Methanesulfonyl)methyl]oxolane