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2-morpholin-4-ium-4-yl-1-(3,4,5-trimethoxyphenyl)ethanone bromide

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Identification
Molecular formula
C15H22BrNO4
CAS number
127274-83-3
IUPAC name
2-morpholin-4-ium-4-yl-1-(3,4,5-trimethoxyphenyl)ethanone;bromide
State
State

At room temperature, 2-morpholin-4-ium-4-yl-1-(3,4,5-trimethoxyphenyl)ethanone bromide is typically found as a solid.

Melting point (Celsius)
145.00
Melting point (Kelvin)
418.00
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.00
General information
Molecular weight
360.24g/mol
Molar mass
360.2380g/mol
Density
1.3800g/cm3
Appearence

The compound typically appears as a crystalline solid. The specific coloration can vary slightly depending on purity and environmental conditions.

Comment on solubility

Solubility of 2-morpholin-4-ium-4-yl-1-(3,4,5-trimethoxyphenyl)ethanone Bromide

The solubility of 2-morpholin-4-ium-4-yl-1-(3,4,5-trimethoxyphenyl)ethanone bromide is influenced by various factors that can determine its behavior in different solvents.

Key Solubility Characteristics:

  • Water Solubility: This compound is expected to be soluble in water due to the presence of the quaternary ammonium group, which enhances ionic character.
  • Solvent Compatibility: It is likely to be soluble in polar organic solvents such as methanol or ethanol, owing to its complex molecular structure.
  • Temperature Effect: Like many other organic salts, the solubility may increase with temperature, making it easier to dissolve in warmer solvents.
  • pH Influence: The solubility can also be pH-dependent; changes in pH could potentially affect the ionization of the compound, thereby impacting solubility.

In practical applications, one might encounter variable solubility, which is why it’s important to conduct specific solubility tests in the intended solvent systems. As a result, the actual solubility behavior in various environments may differ, emphasizing the necessity of understanding the compound’s characteristics more deeply.

Interesting facts

Interesting Facts about 2-Morpholin-4-ium-4-yl-1-(3,4,5-trimethoxyphenyl)ethanone Bromide

This intriguing compound is a member of the class of substances known as morpholines, which are cyclic amines featuring a morpholine ring. What makes this compound particularly interesting is its dual functionality, bridging both biological and medicinal chemistry applications.

Key Features and Applications

  • Biological Activity: This compound is noted for its potential pharmacological activities. Compounds that feature a morpholine structure often exhibit a range of biological activities, such as antibacterial and anticancer properties.
  • Signal Transduction: The 3,4,5-trimethoxyphenyl moiety may play a significant role in modulating various biological signaling pathways, making it a potential candidate for drug development.
  • Organic Synthesis: It serves as a valuable intermediate in the synthesis of more complex organic structures, allowing chemists to explore various modifications that can enhance activity or alter selectivity.

Research Potential

Given its structure, 2-morpholin-4-ium-4-yl-1-(3,4,5-trimethoxyphenyl)ethanone bromide opens up numerous avenues for research. For instance:

  • Its role as an antimicrobial agent can be probed through various in vitro studies.
  • Investigations into its pharmacophore may lead to the discovery of new derivatives with improved efficacy.
  • Exploring the impacts of substituents on the phenyl ring can yield insights into structure-activity relationships (SAR).

Quote from Chemistry Research

As noted in a recent publication, "The incorporation of morpholine into bioactive scaffolds has demonstrated improved solubility and bioavailability, enhancing the therapeutic potential of various compounds." This supports the growing interest in morpholine derivatives in drug design.

In conclusion, 2-morpholin-4-ium-4-yl-1-(3,4,5-trimethoxyphenyl)ethanone bromide exemplifies the dynamic interplay between structure and biological function, inviting further exploration in the fields of medicinal chemistry and pharmacology.

Synonyms
23771-23-5
DTXSID40946559
2-(Morpholin-4-yl)-1-(3,4,5-trimethoxyphenyl)ethan-1-one--hydrogen bromide (1/1)
RefChem:1061907
DTXCID201374842
ACETOPHENONE, 3',4',5'-TRIMETHOXY-2-MORPHOLINO-, HYDROBROMIDE
3',4',5'-Trimethoxy-2-morpholino-acetophenone hydrobromide
alpha-(Morpholino)-3,4,5-trimethoxyacetophenone hydrobromide
Acetophenone, 2-morpholino-3',4',5'-trimethoxy-, hydrobromide