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Loratadine

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Identification
Molecular formula
C22H23ClN2O2
CAS number
79794-75-5
IUPAC name
2-morpholin-4-ium-4-ylethyl 2-ethoxy-3-methoxy-benzoate;chloride
State
State

At room temperature, loratadine exists in a solid state. It is usually encountered in the form of tablets when used as a medication.

Melting point (Celsius)
134.00
Melting point (Kelvin)
407.15
Boiling point (Celsius)
485.60
Boiling point (Kelvin)
758.75
General information
Molecular weight
382.89g/mol
Molar mass
382.8850g/mol
Density
1.2400g/cm3
Appearence

Loratadine is typically a white to off-white crystalline powder. It is practically insoluble in water but soluble in acetone, alcohol, and chloroform.

Comment on solubility

Solubility of 2-morpholin-4-ium-4-ylethyl 2-ethoxy-3-methoxy-benzoate;chloride

The solubility of 2-morpholin-4-ium-4-ylethyl 2-ethoxy-3-methoxy-benzoate;chloride is influenced by several factors, including its ionic nature and the composition of the solvent. This compound is likely to exhibit the following solubility characteristics:

  • High solubility in polar solvents: Due to the presence of the morpholinium ion, this compound is expected to dissolve readily in water and other polar solvents.
  • Reduced solubility in non-polar solvents: Given its ionic characteristics, the solubility in non-polar solvents such as hexane or toluene is likely to be minimal.
  • pH dependency: The solubility may vary with changes in pH, particularly due to the morpholine ring which can be protonated at lower pH levels, enhancing solubility in acidic environments.
  • Temperature effects: Generally, increasing temperature can enhance solubility, but the specific impact on this compound would depend on intermolecular interactions in solution.

As a result, it can be concluded that 2-morpholin-4-ium-4-ylethyl 2-ethoxy-3-methoxy-benzoate;chloride is likely to be highly soluble in polar solvents, making it suitable for various applications where solubility is crucial.

Interesting facts

Interesting Facts About 2-Morpholin-4-ium-4-ylethyl 2-Ethoxy-3-Methoxy-Benzoate; Chloride

This compound, which belongs to the class of ionic liquids, exhibits several intriguing properties that can captivate the attention of chemists and researchers alike. Here are some fascinating aspects:

  • Ionic Nature: As indicated by its chloride component, this compound exhibits ionic characteristics, which can lead to unique solubility and reactivity patterns.
  • Applications: Compounds like this are often explored in various applications ranging from catalysis to pharmaceuticals. Their versatility makes them candidates for innovative research.
  • Structure-Activity Relationship: The presence of the morpholine ring adds interesting cyclic properties to the compound, making it subject to further studies on how variations in structure influence biological activity.
  • Organic Synthesis: The ethoxy and methoxy groups are functional motifs commonly utilized in organic synthesis, serving as protecting groups or reactants in further chemical transformations.
  • Stability and Functionality: Ionic liquids like this compound are often known for their thermal stability and low volatility, which can be favorable characteristics for various practical applications.

As a scientist delving into such compounds, one might ponder how subtle changes in molecular structure can lead to vastly different properties and functions. As the renowned chemist Linus Pauling once said, "The best way to have a good idea is to have a lot of ideas." Therefore, the study of compounds like 2-morpholin-4-ium-4-ylethyl 2-ethoxy-3-methoxy-benzoate; chloride may just unveil novel pathways in drug design, materials science, and catalysis.

Synonyms
22684-79-3
2-Ethoxy-3-methoxybenzoic acid 2-morpholinoethyl ester hydrochloride
DTXSID30945354
2-(Morpholin-4-yl)ethyl 2-ethoxy-3-methoxybenzoate--hydrogen chloride (1/1)
RefChem:1061925
Benzoic acid, 2-ethoxy-3-methoxy-, 2-(4-morpholinyl)ethyl ester, hydrochloride
BENZOIC ACID, 2-ETHOXY-3-METHOXY-, 2-MORPHOLINOETHYL ESTER, HYDROCHLORIDE
DTXCID301373673