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2-Morpholino-1-phenylethanol

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Identification
Molecular formula
C12H17NO2
CAS number
634-13-5
IUPAC name
2-morpholino-1-phenyl-ethanol
State
State

At room temperature, 2-morpholino-1-phenylethanol is typically in a solid state.

Melting point (Celsius)
73.00
Melting point (Kelvin)
346.20
Boiling point (Celsius)
354.20
Boiling point (Kelvin)
627.20
General information
Molecular weight
207.27g/mol
Molar mass
207.2740g/mol
Density
1.1470g/cm3
Appearence

2-Morpholino-1-phenylethanol is typically a white to light yellow crystalline solid. It might also appear as an off-white powder depending on the purity and specific form.

Comment on solubility

Solubility of 2-morpholino-1-phenyl-ethanol

2-morpholino-1-phenyl-ethanol, which features both hydrophilic and lipophilic characteristics due to its structure, has a unique solubility profile that makes it of significant interest in various applications.

This compound is generally considered to be moderately soluble in water. Factors influencing its solubility include:

  • Polar functional groups: The presence of the hydroxyl group (-OH) enhances water solubility, allowing it to interact favorably with water molecules.
  • Hydrophobic regions: The phenyl ring may create some resistance to solvation in polar solvents, which can limit complete solubility.
  • Temperature: As with many organic compounds, increasing the temperature can improve solubility by providing more energy to overcome intermolecular forces.

In organic solvents, 2-morpholino-1-phenyl-ethanol typically exhibits much higher solubility, aligning with the general principle that non-polar compounds dissolve better in non-polar environments. Common solvents where this compound may be well-soluble include:

  • Ethanol
  • Acetone
  • Chloroform

In summary, while 2-morpholino-1-phenyl-ethanol shows favorable solubility in water due to its polar functional groups, its effectiveness can be significantly enhanced in non-polar organic solvents. Understanding these nuances is crucial for its application in pharmaceutical and chemical industries.

Interesting facts

Interesting Facts about 2-Morpholino-1-phenyl-ethanol

2-Morpholino-1-phenyl-ethanol, commonly abbreviated as MPE, is a fascinating compound with diverse applications and intriguing properties. Here are some compelling facts:

  • Pharmacological Interest: This compound has garnered attention in the field of pharmaceuticals. Its structural features make it a candidate for various biological activities, with investigations focusing on its potential as a therapeutic agent.
  • Versatile Applications: Beyond its medicinal properties, MPE is also utilized in other industries. It serves as an important intermediate in the synthesis of complex organic molecules.
  • Unique Structural Features: The morpholino group in MPE contributes significantly to its reactivity and interaction with biological systems. This structural element not only affects the compound's solubility but also its binding interactions with biomolecules.
  • Research Tool: MPE can act as a valuable tool in the study of various biochemical pathways, particularly those involving neurotransmitters. Such studies are essential for understanding neurological disorders.
  • Potential in Drug Design: The knowledge gained from examining MPE can inform the design of novel drugs. Its ability to interact with specific receptors may lead to advancements in treatments for conditions such as anxiety or depression.
  • Chemical Stability: Like many organic compounds, MPE has attributes that influence its stability and reactivity. Understanding these characteristics is crucial for handling and utilizing this compound safely in laboratory settings.

As a compound with potential biological significance and a variety of applications, 2-morpholino-1-phenyl-ethanol is a noteworthy subject of study for both chemists and pharmacologists alike. The exploration of its properties and effects demonstrates the intricate connections between chemical structure and biological function.

Synonyms
4432-34-2
alpha-Phenyl-4-morpholineethanol
4-MORPHOLINEETHANOL, alpha-PHENYL-
1-(beta-Hydroxyphenethyl)morpholine
NSC 400611
BRN 0172769
Benzyl alcohol, alpha-(morpholinomethyl)-
Benzenemethanol, alpha-(4-morpholinylmethyl)-
DTXSID301034887
4-27-00-00160 (Beilstein Handbook Reference)
DTXCID401519383
654-449-8
2-Morpholino-1-phenylethanol
2-morpholin-4-yl-1-phenylethanol
4-Morpholineethanol, .alpha.-phenyl-
2-Morpholino-1-phenylethan-1-ol
Benzenemethanol, .alpha.-(4-morpholinylmethyl)-
.alpha.-Phenyl-4-morpholineethanol
1-(.beta.-Hydroxyphenethyl)morpholine
Benzyl alcohol, .alpha.-(morpholinomethyl)-
NSC400611
Maybridge4_001705
Oprea1_540474
2-morpholino-1-phenyl-ethanol
SCHEMBL1460360
CHEMBL1897032
WLN: T6N DOTJ AYR&1Q
2-morpholino-1-phenyl-1-ethanol
CHEBI:190664
CKCUWHAMJDWXOH-UHFFFAOYSA-N
HMS1525N11
ALBB-026222
MFCD00023377
ZB0051
AKOS001016770
AKOS016050351
2-(4-Morpholinyl)-1-phenylethanol #
NSC-400611
IDI1_032287
NCGC00184356-01
NCGC00184356-02
DB-051209
CS-0327287
H35478
BRD-A88790041-001-01-7
Z31371829