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2-Morpholino-1,2-diphenylethanone

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Identification
Molecular formula
C18H19NO2
CAS number
12771-68-5
IUPAC name
2-morpholino-1,2-diphenyl-ethanone
State
State

At room temperature, it is in a solid state with a crystalline form.

Melting point (Celsius)
110.00
Melting point (Kelvin)
383.15
Boiling point (Celsius)
479.20
Boiling point (Kelvin)
752.35
General information
Molecular weight
281.35g/mol
Molar mass
281.3420g/mol
Density
1.1760g/cm3
Appearence

2-Morpholino-1,2-diphenylethanone typically appears as a white to off-white crystalline powder. The compound is generally stable under normal temperatures and pressures, and it needs to be stored in a cool, dry place.

Comment on solubility

Solubility of 2-Morpholino-1,2-diphenyl-ethanone

2-Morpholino-1,2-diphenyl-ethanone, with its complex structure, exhibits unique solubility characteristics that are noteworthy for its applications. Generally, the solubility of this compound varies significantly depending on the solvent used.

Solubility Characteristics:

  • Polar solvents: 2-Morpholino-1,2-diphenyl-ethanone tends to show good solubility in polar organic solvents such as ethanol and methanol.
  • Non-polar solvents: Conversely, its solubility in non-polar solvents like hexane is quite limited, which can be attributed to the compound's polar functional groups.
  • Water solubility: The solubility in water is generally low, posing challenges for formulations requiring aqueous solutions.

As a rule of thumb, polar compounds are typically more soluble in polar solvents due to the principle of like dissolves like. Therefore, the evaluation of solubility in various media is essential, and this compound is no exception. It's also worth noting that factors such as temperature, pH, and the presence of other solutes can further influence its solubility profile. Understanding these nuances can help in optimizing its application in various chemical processes.

Interesting facts

Interesting Facts about 2-Morpholino-1,2-diphenyl-ethanone

2-Morpholino-1,2-diphenyl-ethanone, often simply referred to as morpholino ketone, is a fascinating compound in the realm of organic chemistry. Here are some key points about this compound:

  • Pharmacological Potential: This compound has garnered interest in the pharmaceutical world due to its potential biological activity. Its unique structure allows for modifications that could enhance efficacy in drug formulations.
  • Chemical Versatility: The presence of both a morpholine ring and diphenyl groups gives this compound unique reactivity characteristics, making it a versatile intermediate in numerous organic synthesis reactions.
  • Role in Material Science: Beyond its applications in medicinal chemistry, 2-morpholino-1,2-diphenyl-ethanone can serve as a photoinitiator in polymers and coatings, allowing it to play a crucial role in material sciences.
  • Research Applications: Its derivatives have been investigated in the context of designing novel therapeutics, showing promise against specific diseases and conditions, including some types of cancer.
  • Structure-Activity Relationship (SAR): The compound contributes significantly to SAR studies, where researchers explore the relationship between chemical structure and biological activity to optimize drug development.

As you delve further into the study of organic compounds, understanding the intricate relationships between structure, reactivity, and potential applications, such as those exhibited by 2-morpholino-1,2-diphenyl-ethanone, will be invaluable. In the words of a famous chemist, “Chemistry is the study of matter, but I prefer to view it as the study of change.” This compound epitomizes that change, exemplifying how a simple structure can lead to a myriad of possibilities in research and application.

Synonyms
794-06-9
SCHEMBL2468109
NSC150064
NSC-150064