Skip to main content

Furazolidone

ADVERTISEMENT
Identification
Molecular formula
C8H7N3O5
CAS number
67-45-8
IUPAC name
2-morpholino-N-[(5-nitro-2-furyl)methyleneamino]acetamide
State
State

At room temperature, Furazolidone is in a solid state, primarily available as a crystalline powder due to its application in medicinal uses.

Melting point (Celsius)
290.00
Melting point (Kelvin)
563.15
Boiling point (Celsius)
463.00
Boiling point (Kelvin)
736.15
General information
Molecular weight
225.15g/mol
Molar mass
225.1840g/mol
Density
1.4478g/cm3
Appearence

Furazolidone appears as yellow crystalline powder. It's known for its relatively bright appearance in powder form.

Comment on solubility

Solubility of 2-morpholino-N-[(5-nitro-2-furyl)methyleneamino]acetamide

The solubility of 2-morpholino-N-[(5-nitro-2-furyl)methyleneamino]acetamide is a topic of interest due to its unique chemical structure. Understanding the solubility of this compound can provide insights into its potential applications and behavior in various solvents.

Key Points on Solubility:

  • Polarity: The presence of functional groups, such as amine and nitro groups, contributes to its overall polarity, which can impact its solubility in polar solvents.
  • Solvent Type: This compound is likely to be more soluble in polar solvents like water or alcohols compared to non-polar solvents due to hydrogen bonding capabilities.
  • Temperature Effects: Like many compounds, an increase in temperature may enhance solubility as it increases molecular motion and encourages interactions with the solvent.
  • pH Influence: The ionization state of the amine group can also play a crucial role in solubility, particularly in aqueous solutions where pH can alter the protonation state.

In summary, the solubility of 2-morpholino-N-[(5-nitro-2-furyl)methyleneamino]acetamide is influenced by various factors, making its study essential for understanding its behavior in different environments. As with many compounds, experimenting with different solvents and conditions will yield more definitive insights into its solubility profile.

Interesting facts

Interesting Facts about 2-morpholino-N-[(5-nitro-2-furyl)methyleneamino]acetamide

2-morpholino-N-[(5-nitro-2-furyl)methyleneamino]acetamide is an intriguing and multifaceted compound that plays a significant role in various fields of research, particularly in medicinal chemistry and pharmacology. Below are some captivating insights into this compound:

  • Pharmacological Interest: This compound has garnered attention due to its potential therapeutic properties. Studies indicate that it may exhibit antitumor activity, making it a candidate for cancer treatment research.
  • Structure-Activity Relationship: The unique structure of 2-morpholino-N-[(5-nitro-2-furyl)methyleneamino]acetamide allows scientists to explore how modifications in molecular structure can impact biological activity, a concept fundamental to drug design.
  • Nitrofuran Moiety: The presence of the nitro group in the furan ring is critical, as it is known to enhance biological activity and can also influence the compound's mechanism of action.

This compound is particularly noteworthy for its potential applications in developing new therapeutics, especially in targeting specific cancer cell lines. In the realm of organic synthesis, chemists focus on optimizing its synthesis methods to improve yield and purity.

As a student or researcher, one might say, "The exploration of compounds like this not only expands our understanding of chemistry but also fuels the advancement of medicinal science." The ongoing research and discovery surrounding this compound illustrate the dynamic nature of chemical science.

Moreover, ongoing investigations into the behavior and interactions of 2-morpholino-N-[(5-nitro-2-furyl)methyleneamino]acetamide contribute significantly to the libraries of drug candidates, highlighting the compound's relevance in contemporary chemical research.

Synonyms
MLS002725680
SMR001596523
2-(4-morpholinyl)-N-[(5-nitro-2-furanyl)methylideneamino]acetamide
2-(morpholin-4-yl)-N'-[(E)-(5-nitrofuran-2-yl)methylidene]acetohydrazide
CHEMBL1905996
Q27164377