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Lenvatinib

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Identification
Molecular formula
C21H19ClN4O4
CAS number
417716-92-8
IUPAC name
(2-morpholinocyclohexyl) N-(2-chloro-6-methyl-phenyl)carbamate
State
State

Lenvatinib is a solid at room temperature.

Melting point (Celsius)
242.90
Melting point (Kelvin)
516.05
Boiling point (Celsius)
494.15
Boiling point (Kelvin)
767.30
General information
Molecular weight
426.84g/mol
Molar mass
426.8440g/mol
Density
1.3917g/cm3
Appearence

Lenvatinib appears as off-white to yellowish solid. It is typically found in a crystalline powder form.

Comment on solubility

Solubility of (2-morpholinocyclohexyl) N-(2-chloro-6-methyl-phenyl)carbamate

The solubility of (2-morpholinocyclohexyl) N-(2-chloro-6-methyl-phenyl)carbamate can be influenced by several factors, including its molecular structure and the type of solvent used. Generally, the solubility of this compound in various solvents can be outlined as follows:

  • Apolar Solvents: Limited solubility may be observed due to the presence of polar functional groups.
  • Polar Aprotic Solvents: Enhanced solubility is likely in solvents like DMSO or acetone, as these can stabilize interactions with the polar sections of the molecule.
  • Aqueous Solutions: It may show poor solubility in water, primarily due to hydrophobic cyclohexyl and chloro-phenyl groups that hinder interaction with water molecules.

As a guiding principle, it is often said: "Like dissolves like." This means that polar solutes tend to dissolve well in polar solvents, while non-polar solutes are more soluble in non-polar solvents. In practical terms, this compound might require specific solvent conditions for optimal solubility.

Understanding the solubility of (2-morpholinocyclohexyl) N-(2-chloro-6-methyl-phenyl)carbamate is essential for applications in pharmaceutical formulations, where solubility can critically affect bioavailability and therapeutic effectiveness.

Interesting facts

Interesting Facts about (2-morpholinocyclohexyl) N-(2-chloro-6-methyl-phenyl)carbamate

(2-morpholinocyclohexyl) N-(2-chloro-6-methyl-phenyl)carbamate, often referred to in the scientific community for its unique structural features, is a compound that belongs to the carbamate family. This compound exhibits several interesting characteristics:

  • Versatile Applications: Due to its structural components, it is primarily studied for its potential use in agricultural chemistry as a pesticide or herbicide, contributing to plant protection in various crops.
  • Synthetic Route: The synthesis of this compound often involves the reaction of various amines with isocyanates, showcasing an excellent method of creating complex organic molecules in the lab.
  • Biological Relevance: Compounds containing cyclic amines, like morpholine, are of great interest in pharmaceuticals due to their ability to interact with biological systems, potentially leading to drug discovery innovations.
  • Safety Profile: As with many chemical compounds, it's important to thoroughly assess the safety and environmental impact of (2-morpholinocyclohexyl) N-(2-chloro-6-methyl-phenyl)carbamate to ensure responsible use in its application domains.

"The intersection of chemistry and environmental sustainability drives innovation in the design of compounds like this one."

Research into this compound not only emphasizes the importance of chemical properties but also spurs discussions about the balance between efficacy and safety in chemical usage, especially in agronomy and pharmaceuticals.