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Tenofovir

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Identification
Molecular formula
C9H14N5O4P
CAS number
147127-20-6
IUPAC name
(2-morpholinocyclohexyl) N-(2,6-dichlorophenyl)carbamate
State
State

Tenofovir is typically in a solid state at room temperature. It is more commonly found in its salt or prodrug forms, which are used in medications.

Melting point (Celsius)
255.00
Melting point (Kelvin)
528.20
Boiling point (Celsius)
557.10
Boiling point (Kelvin)
830.20
General information
Molecular weight
287.22g/mol
Molar mass
287.2150g/mol
Density
1.3400g/cm3
Appearence

Tenofovir is a white to off-white powder with no distinctive odor. It is commonly supplied in its prodrug form such as tenofovir disoproxil fumarate or tenofovir alafenamide, which are both white solids.

Comment on solubility

Solubility of (2-morpholinocyclohexyl) N-(2,6-dichlorophenyl)carbamate

The solubility of the compound (2-morpholinocyclohexyl) N-(2,6-dichlorophenyl)carbamate is influenced by several factors, which can be important for its application in various fields. Generally, the solubility characteristics can be summarized as follows:

  • Polarity: The presence of polar functional groups in the structure, such as the morpholine and carbamate moieties, often enhances solubility in polar solvents like water.
  • Hydrophobic regions: The cyclohexyl ring introduces a hydrophobic part, which may reduce solubility in aqueous environments, potentially limiting its use in water-based applications.
  • Temperature dependence: Solubility may increase with temperature changes, making high-temperature solvents more favorable for dissolving this compound.
  • pH sensitivity: The solubility of this compound can vary significantly based on the pH of the solvent, with acidic or basic conditions potentially altering the ionization of the functional groups.

In summary, while (2-morpholinocyclohexyl) N-(2,6-dichlorophenyl)carbamate can demonstrate notable solubility in suitable conditions, understanding its complete solubility profile requires careful consideration of the interplay between its molecular structure and the solvent environment. As the saying goes, "like dissolves like," highlighting the importance of matching polarity in solvent selection.

Interesting facts

Interesting Facts about (2-Morpholinocyclohexyl) N-(2,6-dichlorophenyl)carbamate

(2-Morpholinocyclohexyl) N-(2,6-dichlorophenyl)carbamate is a fascinating compound with a range of intriguing properties and potential applications. Here are some key points to consider:

  • Chemical Group: This compound belongs to the class of carbamates, which are esters or derivatives of carbamic acid. Carbamates are known for their roles in agriculture as pesticides and herbicides.
  • Biological Significance: The presence of the morpholine ring suggests that this compound may interact with biological systems in a unique way, potentially influencing neurotransmitter pathways.
  • Substituent Effects: The 2,6-dichlorophenyl group adds significant steric and electronic effects that may enhance the biological activity of the compound, making it of interest for pharmacological studies.
  • Research Applications: There is ongoing research into carbamate compounds for their potential use in drug development, particularly in targeting specific diseases or cellular pathways.
  • Environmental Impact: Understanding the behavior of carbamates in the environment is crucial, as they can break down into toxic byproducts. Studies often focus on assessing their eco-toxicity and degradation pathways.
  • Interaction Studies: Research has shown that derivatives containing the morpholine group can act as inhibitors or activators of various enzymes, which is an area of interest for scientists looking to develop new therapeutic strategies.

In summary, (2-Morpholinocyclohexyl) N-(2,6-dichlorophenyl)carbamate is more than just a chemical compound; it is a subject of extensive study that bridges the worlds of organic chemistry, pharmacology, and environmental science. Its unique structure and properties make it an exciting area of exploration for both researchers and chemists alike.