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2-(morpholinomethyl)tetralin-1-one

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Identification
Molecular formula
C15H21NO2
CAS number
/
IUPAC name
2-(morpholinomethyl)tetralin-1-one
State
State

At room temperature, this compound is in a solid state.

Melting point (Celsius)
89.00
Melting point (Kelvin)
362.15
Boiling point (Celsius)
356.70
Boiling point (Kelvin)
629.85
General information
Molecular weight
259.34g/mol
Molar mass
259.3390g/mol
Density
1.2065g/cm3
Appearence

2-(Morpholinomethyl)tetralin-1-one typically appears as a solid at room temperature. Its precise appearance can vary from white to off-white crystalline powder.

Comment on solubility

Solubility of 2-(morpholinomethyl)tetralin-1-one

The solubility of 2-(morpholinomethyl)tetralin-1-one can be quite interesting due to its unique structure. This compound features a tetralin core, which is primarily hydrophobic, surrounded by a morpholinomethyl group that can interact more favorably with polar solvents.

When considering its solubility, the following factors are essential:

  • Polarity: The presence of the morpholine group may increase the overall polarity of the molecule, leading to enhanced solubility in polar solvents such as water and alcohols.
  • Hydrogen Bonding: The morpholine moiety can participate in hydrogen bonding, further aiding its solubility in aqueous environments.
  • Hydrophobic Interactions: Conversely, the tetralin portion can introduce hydrophobic characteristics, which might hinder solubility in highly polar solvents.

In practical terms, one might expect 2-(morpholinomethyl)tetralin-1-one to be more soluble in polar organic solvents, such as ethanol or methanol, while its solubility in water might be limited compared to fully hydrophilic compounds.

Overall, the solubility of this compound is a balance of its structural components, making it a noteworthy subject of study in the realm of solubility behavior.

Interesting facts

Interesting Facts about 2-(Morpholinomethyl)tetralin-1-one

2-(Morpholinomethyl)tetralin-1-one is a fascinating compound with a variety of notable attributes. Here are some insightful points of interest:

  • Pharmaceutical Relevance: This compound belongs to a class of organic compounds often explored for their potential pharmacological properties. It may be used as a precursor in the synthesis of various pharmaceuticals, making it valuable in medicinal chemistry.
  • Structural Diversity: The structure of 2-(morpholinomethyl)tetralin-1-one incorporates a morpholine ring, which is known for its usefulness in enhancing biological activity and solubility. Morpholine derivatives are considered to be key components in drug discovery.
  • Research Potential: Due to its unique structure, this compound can serve as a target for further research. Scientists often look at similar compounds to understand their interactions and develop new therapeutics that may help in treating certain diseases.
  • Interdisciplinary Applications: Beyond medicinal chemistry, the properties of this compound can be studied in fields such as materials science and organic synthesis, showcasing the versatile applications of tetralin derivatives.
  • Quote from a Researcher: "Compounds like 2-(morpholinomethyl)tetralin-1-one challenge our understanding of structure-activity relationships in drug design, opening doors to novel therapeutic avenues."

Overall, 2-(morpholinomethyl)tetralin-1-one exemplifies the intriguing intersection of organic chemistry and pharmacology, illustrating how structural elements can influence biological function and drug efficacy.

Synonyms
2-(4-morpholinylmethyl)-3,4-dihydro-1(2h)-naphthalenone
Oprea1_025946
7353-60-8
CHEMBL3302800
DTXSID30274752
1(2H)-Naphthalenone, 3,4-dihydro-2-(4-morpholinylmethyl)-
2-(morpholinomethyl)tetralin-1-one
AO-840/42717745