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N-Phenyl-ethanolamine

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Identification
Molecular formula
C10H15NO2
CAS number
92-35-3
IUPAC name
2-[N-(2-hydroxyethyl)anilino]ethanol
State
State

At room temperature, N-Phenyl-ethanolamine can exist as either a liquid or a solid. In its pure form, it is often a colorless to pale yellow solid that is slightly soluble in water, but it may also be found as a liquid in certain conditions.

Melting point (Celsius)
41.00
Melting point (Kelvin)
314.15
Boiling point (Celsius)
305.50
Boiling point (Kelvin)
578.70
General information
Molecular weight
167.22g/mol
Molar mass
167.2150g/mol
Density
1.1590g/cm3
Appearence

N-Phenyl-ethanolamine typically appears as a colorless to pale yellow liquid or solid. It may sometimes form as a crystalline powder depending on its specific formulation and purity level. The compound is hygroscopic, meaning it can absorb moisture from the air.

Comment on solubility

Solubility of 2-[N-(2-hydroxyethyl)anilino]ethanol

The solubility of 2-[N-(2-hydroxyethyl)anilino]ethanol, a compound with unique functional groups, can be interesting to explore due to its potential applications in various fields. Here are some key points regarding its solubility:

  • Polar Nature: The presence of hydroxyl groups (-OH) and amino groups (-NH) in the structure of 2-[N-(2-hydroxyethyl)anilino]ethanol suggests that it is likely to be polar, which enhances its ability to dissolve in polar solvents such as water.
  • Hydrophilicity: Compounds with hydrophilic functional groups tend to attract water molecules, making them soluble. Therefore, it can be expected that 2-[N-(2-hydroxyethyl)anilino]ethanol can be readily dissolved in aqueous solutions.
  • Influence of pH: The solubility of this compound may also be influenced by the pH of the solution. Changes in pH can affect the ionization of the amino group, potentially increasing the solubility in more acidic or alkaline environments.
  • Organic Solvents: In addition to water, this compound may also exhibit some solubility in organic solvents, particularly those with polar characteristics.

In summary, while detailed solubility data may be needed for precise applications, it is reasonable to state that 2-[N-(2-hydroxyethyl)anilino]ethanol shows good solubility in both polar solvents, such as water, and possibly compatible organic solvents, owing to its hydrophilic character.

Interesting facts

Interesting Facts about 2-[N-(2-hydroxyethyl)anilino]ethanol

2-[N-(2-hydroxyethyl)anilino]ethanol, more commonly known as a derivative of amino alcohols, has several intriguing characteristics that make it worthy of attention in the field of chemistry:

  • Versatile Applications: This compound is used in various fields such as pharmaceuticals, where it acts as an important building block for developing active pharmaceutical ingredients.
  • Biological Relevance: The presence of the hydroxyl group contributes to its solubility and reactivity, making it a suitable candidate for drug design and development, assisting in creating compounds with potential therapeutic benefits.
  • Structure Insight: The unique structure that includes both an aniline and ethanolamine component allows it to participate in various chemical reactions, notably nucleophilic substitutions and amine reactivity, enhancing its utility in organic synthesis.
  • Potential in Research: Researchers are investigating its role in biochemical pathways and its interaction with biological systems, paving the way for advancements in medicinal chemistry.
  • Safety and Handling: As with many chemical compounds, proper safety measures should be followed when handling 2-[N-(2-hydroxyethyl)anilino]ethanol to mitigate any health risks associated with exposure.

Overall, 2-[N-(2-hydroxyethyl)anilino]ethanol exemplifies the complex interplay between chemical structure and functionality, bridging the gap between basic research and practical application. As we continue to explore its properties and potential, it holds promise for innovative developments in various scientific domains.

Synonyms
N-Phenyldiethanolamine
120-07-0
2,2'-(Phenylimino)diethanol
N-Phenyl diethanolamine
Diethanolaniline
PHENYLDIETHANOLAMINE
N,N-Diethanolaniline
Diethanolphenylamine
Diethanolaminobenzene
Phenyl diethanolamine
N,N-Dioxyethylaniline
Ethanol, 2,2'-(phenylimino)bis-
N,N-Bis(2-hydroxyethyl)aniline
Phenylbis(2-hydroxyethyl)amine
2-[N-(2-hydroxyethyl)anilino]ethanol
N-Phenyl-N,N-diethanolamine
2,2'-(Phenylamino)diethanol
Emery 5703
Dihydroxyethylaniline
N,N-Di(2-hydroxyethyl)aniline
2,2'-Phenyliminodiethanol
N,N-Dihydroxyethylaniline
2,2'-(phenylazanediyl)diethanol
N,N-Bis(beta-hydroxyethyl)aniline
Ethanol, 2,2'-(phenylimino)di-
NSC 6327
N,N-Di(beta-hydroxyethyl)aniline
(Bis(2-hydroxyethyl)amino)benzene
EINECS 204-368-5
2,2-(Phenylimino)diethanol
BRN 2096832
DTXSID5021962
AI3-01739
Di(hydroxyethyl)aniline
VE25V5K077
NSC-6327
DTXCID501962
2,2/'-(Phenylimino)diethanol
2-[(2-hydroxyethyl)(phenyl)amino]ethan-1-ol
[Bis(2-hydroxyethyl)amino]benzene
N,N-Di(.beta.-hydroxyethyl)aniline
MFCD00002845
N,N-Bis(.beta.-hydroxyethyl)aniline
2,2'-(PHENYLIMINO)BIS(ETHANOL)
3-PHENYL-3-AZAPENTANE-1,5-DIOL
2-((2-HYDROXYETHYL)PHENYLAMINO)ETHANOL
UNII-VE25V5K077
N,NDiethanolaniline
N,NDioxyethylaniline
NPhenyldiethanolamine
N-phenyldiethanol amine
NPhenylN,Ndiethanolamine
2,2'Phenyliminodiethanol
Maybridge1_000066
MixCom1_000110
2,2'(Phenylamino)diethanol
2,2'(Phenylimino)diethanol
N,NDi(2hydroxyethyl)aniline
Oprea1_106708
SCHEMBL78451
N,NBis(2hydroxyethyl)aniline
Phenylbis(2hydroxyethyl)amine
N-Phenyldiethanolamine, 97%
Ethanol,2'-(phenylimino)di-
N,NDi(betahydroxyethyl)aniline
Ethanol,2'-(phenylimino)bis-
N-Phenyl-2,2'-iminodiethanol
2,2\'-(Phenylimino)diethanol
Ethanol, 2,2'(phenylimino)di
N,NBis(betahydroxyethyl)aniline
WLN: Q2NR & 2Q
CHEMBL3188755
Ethanol, 2,2'(phenylimino)bis
(Bis(2hydroxyethyl)amino)benzene
n,n-bis(2-hydroxyethyl)-aniline
NSC6327
CHEBI:194838
aniline, N,N-bis(2-hydroxyethyl)-
Tox21_301523
AKOS000268987
CS-W017150
2-[(2-hydroxyethyl)anilino]ethan-1-ol
NCGC00255359-01
AC-11088
CAS-120-07-0
LS-13825
NS00015637
P0187
D78164
EN300-383883
Q27291780
Z336079346
InChI=1/C10H15NO2/c12-8-6-11(7-9-13)10-4-2-1-3-5-10/h1-5,12-13H,6-9H