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N-Propyl-N'-nitroguanidine

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Identification
Molecular formula
C4H10N4O3
CAS number
25686-28-6
IUPAC name
2-nitro-1-nitroso-1-propyl-guanidine
State
State

At room temperature, N-Propyl-N'-nitroguanidine is generally found in a solid state. Its stability can be affected by temperature changes, and it is usually stored under specific conditions to prevent decomposition.

Melting point (Celsius)
144.00
Melting point (Kelvin)
417.15
Boiling point (Celsius)
146.00
Boiling point (Kelvin)
419.15
General information
Molecular weight
160.14g/mol
Molar mass
160.1250g/mol
Density
1.2200g/cm3
Appearence

N-Propyl-N'-nitroguanidine is typically characterized as a solid crystal or powder. It exhibits a pale yellow to yellow coloration and must be handled with care as it can be sensitive to various conditions, including mechanical impact and static discharge.

Comment on solubility

Solubility of 2-nitro-1-nitroso-1-propyl-guanidine

The solubility of 2-nitro-1-nitroso-1-propyl-guanidine can be influenced by several factors, including the molecular structure and the presence of functional groups. Here are some key points regarding its solubility:

  • Polarity: The presence of nitro and nitroso functional groups typically increases the polarity of the compound, which can enhance solubility in polar solvents such as water.
  • Hydrogen Bonding: The guanidine moiety suggests the potential for hydrogen bonding, which could further facilitate solubility in solvent systems that can form hydrogen bonds.
  • Solvent Compatibility: Generally, compounds with similar polarities are more soluble in one another. Therefore, 2-nitro-1-nitroso-1-propyl-guanidine might exhibit better solubility in organic solvents like methanol or ethanol compared to non-polar solvents.

However, the exact solubility characteristics of this compound can vary significantly based on experimental conditions. It is often beneficial to conduct solubility tests in different solvents to determine the most effective solvent for its application. As a general rule, like dissolves like, so understanding the interactions between solvents and solutes is crucial in predicting solubility behavior.


In summary, while specific solubility data for 2-nitro-1-nitroso-1-propyl-guanidine may not be widely available, the structural features point towards a likelihood of reasonable solubility in polar solvents, particularly those that permit hydrogen bonding.

Interesting facts

Interesting Facts About 2-Nitro-1-nitroso-1-propyl-guanidine

2-Nitro-1-nitroso-1-propyl-guanidine is a remarkable compound that captures the attention of both chemists and researchers alike due to its intricate structure and diverse applications. Here are some intriguing points about this compound:

  • Historical Significance: This compound has been studied for its potential role in medicinal chemistry, particularly in the development of pharmaceuticals. Its nitro and nitroso functionalities contribute to its biological activity.
  • Reactivity: The presence of nitro and nitroso groups in the molecular structure can lead to interesting reactivity patterns, making it a subject of interest in synthetic organic chemistry.
  • Applications: Researchers have explored its efficacy in various fields, including:
    • As a potential anti-cancer agent.
    • In agricultural research for pest control and growth regulation.
  • Structure-Activity Relationship (SAR): The unique combination of functional groups allows chemists to study how structural modifications can alter the biological activity, aiding in drug development.
  • Analytical Techniques: The analysis of this compound often involves sophisticated techniques such as mass spectrometry and nuclear magnetic resonance (NMR), allowing for a deeper understanding of its properties and behavior in different environments.

In summary, 2-nitro-1-nitroso-1-propyl-guanidine is more than just a chemical entity; it represents a gateway to exploring the vast potential of nitro-based compounds in modern science. As one researcher aptly put it, "The study of such compounds not only broadens our horizons in chemical understanding but also paves the way for future breakthroughs in technology and medicine."

Synonyms
SCHEMBL11478654
CID 25591