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2-nitroimidazole

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Identification
Molecular formula
C3H3N3O2
CAS number
527-73-1
IUPAC name
2-nitro-1H-imidazole
State
State

Solid: 2-Nitroimidazole is typically found in a solid state at room temperature, usually as a crystalline powder.

Melting point (Celsius)
161.00
Melting point (Kelvin)
434.15
Boiling point (Celsius)
230.00
Boiling point (Kelvin)
503.15
General information
Molecular weight
113.08g/mol
Molar mass
113.0820g/mol
Density
1.5200g/cm3
Appearence

2-Nitroimidazole is a yellow solid compound. As a nitroimidazole derivative, it typically forms crystals and can be powdered for various applications. It is not hygroscopic and maintains its structure under normal atmospheric conditions.

Comment on solubility

Solubility of 2-Nitro-1H-Imidazole

2-Nitro-1H-imidazole is an intriguing compound when it comes to its solubility characteristics. Understanding the solubility of this substance can provide valuable insights into its behavior in various chemical environments.

Factors Influencing Solubility:

  • Polarity: The presence of the nitro group (-NO2) in 2-nitro-1H-imidazole contributes to its overall polarity, which can enhance its solubility in polar solvents.
  • Hydrogen Bonding: This compound can engage in hydrogen bonding due to its imidazole ring, further affecting its interaction with solvents.
  • Temperature: Like many chemical compounds, the solubility of 2-nitro-1H-imidazole tends to increase with temperature, allowing for greater solvation of the molecules.

Generally, 2-nitro-1H-imidazole has moderate solubility in water and is more soluble in organic solvents such as dimethyl sulfoxide (DMSO) and ethanol. As a result, it is crucial to consider the solvent system when working with this compound in research and industrial applications.

In summary, the solubility of 2-nitro-1H-imidazole is governed by its structural features and the nature of the surrounding medium. Exploring these properties can yield important information about its potential applications and behavior in chemical reactions.

Interesting facts

Interesting Facts about 2-nitro-1H-imidazole

2-nitro-1H-imidazole is a fascinating compound with a rich history and a variety of applications in the fields of chemistry and medicine. Here are some key points that make this compound noteworthy:

  • Antimicrobial Properties: 2-nitro-1H-imidazole belongs to a class of compounds known for their antimicrobial activity, which has led to its investigation as a potential treatment option for various bacterial infections.
  • Mechanism of Action: This compound operates primarily by disrupting DNA synthesis in bacteria, a critical process for their reproduction and survival. This mechanism makes it a potent candidate for developing new antibiotics.
  • Research Applications: Due to its unique structure, it serves as an important building block in synthetic organic chemistry, allowing scientists to create a range of derivatives with enhanced biological activity.
  • Analytical Importance: 2-nitro-1H-imidazole is often used as a probe in biochemical assays, helping researchers to understand cellular processes and interactions at a molecular level.
  • Versatile Functionalization: The presence of the nitro group allows for various chemical reactions, such as reduction or substitution, which enhances the compound's utility in organic synthesis.

In conclusion, 2-nitro-1H-imidazole not only exemplifies the diverse nature of chemical compounds but also highlights the importance of continuing research into its potential applications. As scientists explore its properties further, we may discover even more about its significance in medical and synthetic chemistry.

Synonyms
2-Nitroimidazole
Azomycin
nitroimidazole
1H-Imidazole, 2-nitro-
36877-68-6
EINECS 208-425-5
Azomycin [MI]
NSC 105831
BRN 0116444
K8E96XL55D
CHEBI:67135
NSC-105831
UNII-K8E96XL55D
DTXSID7060178
DTXCID6041260
5-23-04-00471 (beilstein handbook reference)
yzeuhqhuftylph-uhfffaoysa-n
527-73-1
2-NITRO-1H-IMIDAZOLE
Amicin
Imidazole, 2-nitro-
MFCD00005185
Ro 05-9129
Azomycin (2-Nitroimidazole)
NSC105831
Nitroimidazoles
2-Nitroimidazol
2 -nitroimidazole
2-nitro-imidazole
2-Nitroimidazole, 98%
2-Aci-nitro-2H-imidazole
WLN: T5M CNJ BNW
azomycin-(2-nitroimidazole)
SCHEMBL10049
YSWG910
875208-30-3
MLS006010891
CHEMBL433637
SCHEMBL4794199
SCHEMBL17145914
HMS3655N18
ALBB-016499
BCP26458
CS-D1102
HY-N0195
BBL100949
s2267
STL554743
AKOS006222773
AKOS007929923
CCG-208568
FN16080
NCGC00346715-01
AS-14901
SMR004701806
SY019543
DB-006205
DB-216935
A7707
N0891
NS00011814
SW220260-1
EN300-84202
SR-05000002197
SR-05000002197-2
BRD-K26824830-001-02-0
BRD-K26824830-001-03-8
Q27135639
Z1203162379