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2-Nitrobenzamide

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Identification
Molecular formula
C7H6N2O3
CAS number
552-89-6
IUPAC name
2-nitrobenzamide
State
State

At room temperature, 2-Nitrobenzamide is typically in a solid state, often in the form of yellow to orange crystals. This solid nature is characteristic of many aromatic amides with a nitro group substitution.

Melting point (Celsius)
140.50
Melting point (Kelvin)
413.70
Boiling point (Celsius)
66.30
Boiling point (Kelvin)
339.50
General information
Molecular weight
152.14g/mol
Molar mass
152.1250g/mol
Density
1.4772g/cm3
Appearence

2-Nitrobenzamide is a yellow to orange crystalline solid. It may appear as a powder or granular compound and is known for its distinct coloration due to the nitro group attached to the benzene ring.

Comment on solubility

Solubility of 2-nitrobenzamide

2-nitrobenzamide, with the chemical formula C7H6N2O3, exhibits intriguing solubility characteristics in various solvents, which are essential to its applications in organic synthesis and medicinal chemistry. Understanding its solubility can provide insights into its behavior in different environments.

Solubility Characteristics

The solubility of 2-nitrobenzamide can be summarized as follows:

  • Water: 2-nitrobenzamide has limited solubility in water, making it a moderately polar compound.
  • Organic Solvents: It is more soluble in various organic solvents such as:
    • Acetone
    • Ethyl acetate
    • DMSO (Dimethyl sulfoxide)
  • Thermal Behavior: Solubility can increase with temperature, which is frequently observed in solid organic compounds.

In summary, 2-nitrobenzamide's solubility profile highlights its preference for organic mediums, aligning with many compounds that possess functional groups impacting their hydrophilicity and lipophilicity. As the saying goes, "Like dissolves like", emphasizing that polar solvents are less effective for apolar compounds, aligning well with 2-nitrobenzamide's properties.

Interesting facts

Interesting Facts about 2-Nitrobenzamide

2-Nitrobenzamide is a significant organic compound that plays an essential role in various chemical and industrial processes. Here are some interesting aspects of this compound:

  • Functional Group: It features a nitro group (-NO2) attached to the aromatic benzamide, making it an important precursor in the synthesis of other compounds.
  • Synthetic Applications: This compound is widely used in the synthesis of pharmaceuticals and agrochemicals, thanks to its ability to participate in nucleophilic reactions.
  • Biological Activity: 2-Nitrobenzamide has shown potential biological activity, with studies indicating it may have antimicrobial and antifungal properties.
  • Research Interest: It has attracted significant research interest in the fields of medicinal chemistry and material science due to its versatile reactivity.
  • Environmental Concerns: Being a nitro compound, it is essential to handle 2-nitrobenzamide with care due to potential environmental implications, including bioaccumulation and toxicity.

In conclusion, 2-nitrobenzamide is not just a chemical compound but also a tool of immense utility in the scientific realm. Its diverse applications and intriguing properties make it a topic of interest for researchers and students alike. As the chemist Linus Pauling once said, "Science is not only compatible with spirituality; it is a profound source of spirituality." Embracing compounds like 2-nitrobenzamide enriches our understanding of the intricate tapestry of chemical interactions and their applications.

Synonyms
2-Nitrobenzamide
610-15-1
O-NITROBENZAMIDE
DTXSID0025733
DTXCID005733
oNitrobenzamide
Benzamide, onitro
Benzamide, 2nitro
2Carbamoylnitrobenzene
Benzamide, 2nitro (9CI)
210-208-5
Benzamide, o-nitro-
Benzamide, 2-nitro-
2-Carbamoylnitrobenzene
nitrobenzamide
2-nitro-benzamide
MFCD00007976
EINECS 210-208-5
NSC 407995
BRN 1950928
nitro-benzamide
NSC407995
Benzmide, 2-nitro-
WLN: ZVR BNW
2-Nitrobenzamide, 98%
MLS002415764
SCHEMBL115478
CHEMBL1876019
SCHEMBL10766788
HMS3039B14
Tox21_200805
AKOS003264457
AKOS015889353
FN71268
NSC-407995
NCGC00091242-01
NCGC00091242-02
NCGC00258359-01
AS-56770
CAS-610-15-1
NCI60_003903
SMR001370920
SY106197
DB-053767
N0322
NS00014385
D91678
EN300-370498
AQ-776/40170836
Q63409300
F1084-0243
InChI=1/C7H6N2O3/c8-7(10)5-3-1-2-4-6(5)9(11)12/h1-4H,(H2,8,10