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2-Nitrobenzoyl chloride

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Identification
Molecular formula
C7H4ClNO3
CAS number
577-23-5
IUPAC name
2-nitrobenzoyl chloride
State
State

At room temperature, 2-nitrobenzoyl chloride exists as a solid.

Melting point (Celsius)
42.50
Melting point (Kelvin)
315.65
Boiling point (Celsius)
261.00
Boiling point (Kelvin)
534.00
General information
Molecular weight
185.56g/mol
Molar mass
185.5640g/mol
Density
1.3990g/cm3
Appearence

2-Nitrobenzoyl chloride is a pale yellow solid. It can sometimes appear slightly brownish due to impurities. It has a pungent and unpleasant odor, characteristic of acyl chlorides.

Comment on solubility

Solubility of 2-nitrobenzoyl chloride

2-nitrobenzoyl chloride, with the chemical formula C7H4ClNO3, is known for its intriguing solubility properties. This compound exhibits varying solubility in different solvents, which can be summarized as follows:

  • Organic Solvents: 2-nitrobenzoyl chloride is generally soluble in organic solvents such as ethanol, acetone, and chloroform. This characteristic makes it useful in organic synthesis and various reactions.
  • Aqueous Solubility: The compound has very low solubility in water, which is typical for substances containing chlorides and certain nitro groups. This limited solubility can affect its reactivity in aqueous environments.
  • Influence of Temperature: It's important to note that temperature can affect solubility. As described in various studies, increases in temperature typically enhance the solubility of organic compounds.

In conclusion, while 2-nitrobenzoyl chloride shows considerable solubility in organic solvents, its low solubility in water highlights the need for careful solvent selection in practical applications. As with many chemical compounds, the solubility characteristics are crucial for understanding its behavior in chemical reactions and processes.

Interesting facts

Interesting Facts about 2-Nitrobenzoyl Chloride

2-Nitrobenzoyl chloride is a fascinating compound in the field of organic chemistry, particularly due to its role in various chemical reactions. Here are some engaging facts:

  • Esterification Reactions: This compound is commonly used in the synthesis of esters. By reacting with alcohols, it can produce useful ester derivatives that are found in flavors and fragrances.
  • Precursor in Synthesis: 2-Nitrobenzoyl chloride serves as a key intermediate in the formation of various pharmaceuticals and agrochemicals, showcasing its importance in medicinal chemistry.
  • Reaction with Amines: When this compound interacts with amines, it can form amides, which are essential in the production of proteins and other polymers.
  • Electrophilic Substitution: Due to the presence of both the nitro group and the acyl chloride group, it can undergo electrophilic substitution reactions with aromatic compounds, leading to complex chemical structures.
  • Safety Considerations: As a reactive acyl chloride, it should be handled with caution; it can hydrolyze in the presence of moisture, releasing hydrochloric acid and potentially leading to corrosive hazards.

In summary, 2-nitrobenzoyl chloride is not just a simple compound but a vital building block in organic synthesis, demonstrating its versatility and significance in chemical research and industrial applications. As researchers continue to explore its potential, the future of this compound may yield even more innovative applications!


Synonyms
2-Nitrobenzoyl chloride
O-NITROBENZOYL CHLORIDE
Benzoyl chloride, 2-nitro-
CCRIS 3135
o-nitrobenzoic acid chloride
EINECS 210-206-4
UNII-86W2G0JA5Q
BRN 0777991
86W2G0JA5Q
DTXSID4025741
DTXCID505741
NITROBENZOYL CHLORIDE, O-
4-09-00-01049 (Beilstein Handbook Reference)
2-nitro benzoyl chloride
ORTHO-NITROBENZOYL CHLORIDE
2-NITROBENZOIC ACID, CHLORIDE
bwwhtihdqbhthp-uhfffaoysa-n
610-14-0
Benzoyl chloride, o-nitro-
Nitrobenzoyl chloride
2-Nitrobenzoylchloride
MFCD00007131
2-nitro-benzoyl chloride
SCHEMBL103644
2-Nitrobenzoyl chloride, 97%
CHEMBL1897082
Tox21_200340
STL301450
AKOS005259174
FS-3815
NCGC00091764-01
NCGC00091764-02
NCGC00257894-01
CAS-610-14-0
DB-053766
NS00034524
EN300-26497
2-Nitrobenzoyl chloride, purum, >=97.0% (T)
A833004
Q27269768