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2-nitroethanol

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Identification
Molecular formula
C2H5NO3
CAS number
625-48-9
IUPAC name
2-nitroethanol
State
State

At room temperature, 2-nitroethanol is a liquid. It is known to be stable under recommended storage conditions, though it should be kept in tightly sealed containers to prevent absorption of moisture and degradation.

Melting point (Celsius)
12.00
Melting point (Kelvin)
285.15
Boiling point (Celsius)
206.00
Boiling point (Kelvin)
479.15
General information
Molecular weight
91.07g/mol
Molar mass
91.0730g/mol
Density
1.1269g/cm3
Appearence

2-Nitroethanol appears as a colorless to pale yellow liquid with a characteristic alcoholic odor. It is hygroscopic in nature, absorbing moisture from the air. It is generally clear, though it can acquire a slight yellowish hue upon prolonged exposure to light and air due to oxidation.

Comment on solubility

Solubility of 2-nitroethanol

2-nitroethanol, with the chemical formula C2H6N2O3, is a unique and interesting compound when it comes to solubility. This compound is primarily known for its solubility in various solvents, which enhances its utility in different applications. Here are some key points:

  • Water Solubility: 2-nitroethanol is highly soluble in water due to its ability to form hydrogen bonds, making it an excellent solvent in aqueous environments.
  • Organic Solvents: This compound is also soluble in a range of organic solvents such as alcohols, ether, and other polar solvents, expanding its applicability in organic synthesis.
  • Temperature Influence: The solubility may vary with temperature. For instance, an increase in temperature can enhance the solubility of 2-nitroethanol in water.
  • Miscibility: It is important to note that 2-nitroethanol can be completely miscible with a variety of solvents, which is advantageous in chemical processes.

In summary, the solubility profile of 2-nitroethanol is a critical attribute that supports its use in various chemical reactions and applications. Its excellent solubility in both water and organic solvents makes it a versatile compound in the laboratory setting.

Interesting facts

Exploring 2-Nitroethanol

2-Nitroethanol, also known as nitroethanol or nitroethyl alcohol, is a fascinating compound with a variety of applications and properties that make it of interest to chemists and industrial researchers alike.

Key Properties and Uses

  • Protic Solvent: 2-Nitroethanol is an effective protic solvent, making it an excellent medium for various chemical reactions.
  • Precursor: It serves as a valuable intermediate in the synthesis of agrochemicals, pharmaceuticals, and other nitro compounds.
  • Research Material: This compound plays a crucial role in organic chemistry as a subject of study, particularly in investigating reaction mechanisms.

Chemical Reactivity

The compound's reactivity is profoundly influenced by the nitro group (-NO2), which not only enhances its electrophilic character but also helps in polarizing the C-N bond. Some notable reactions include:

  1. Nucleophilic Substitution: 2-Nitroethanol can engage in nucleophilic substitution reactions, making it a versatile building block in organic synthesis.
  2. Reduction: Under certain conditions, it may be reduced to more reactive amines, showcasing its potential in producing various derivatives.

Safety and Handling

While 2-nitroethanol is utilized in various industrial applications, it is essential to handle it with care due to its toxicity. Researchers and students should emphasize the following safety protocols:

  • Always wear appropriate personal protective equipment (PPE), including gloves and goggles.
  • Work in a well-ventilated area to prevent inhalation of fumes.
  • Be aware of its potential environmental impacts and dispose of any waste responsibly.

A Fun Fact

Did you know? The nitro group in 2-nitroethanol not only affects its chemical behavior but also contributes to distinctive flavor profiles when used in trace amounts in analytical and food chemistry. Its utility extends beyond traditional applications, showcasing how a single functional group can drastically influence chemical properties.

In conclusion, 2-nitroethanol is a compound that exemplifies the intricate relationship between structure and function within chemistry. Its diverse applications and reactivity pattern continue to inspire research and innovation.

Synonyms
2-NITROETHANOL
625-48-9
Ethanol, 2-nitro-
CCRIS 6076
EINECS 210-895-1
NSC 16151
BRN 1633753
DTXSID8025751
AI3-28038
.beta.-Nitroethyl alcohol
DTXCID805751
4-01-00-01388 (Beilstein Handbook Reference)
beta-Nitroethyl alcohol
1-NITRO-2-HYDROXYETHANE
210-895-1
inchi=1/c2h5no3/c4-2-1-3(5)6/h4h,1-2h
kipmdpdafinliv-uhfffaoysa-n
2-nitroethan-1-ol
2-Nitro-ethanol
.beta.-Nitroethanol
MFCD00007405
beta-Nitroalcohol
beta-Nitroethanol
2-Nitroethanol; NSC 16151; ss-Nitroethano;
NSC16151
2-Nitro-1-ethanol
2-Nitroethanol, 97%
MLS002152877
CHEMBL324774
HMS3039F14
Tox21_200622
AC1643
NSC-16151
AKOS009085428
AB00877
CS-W013741
FN07840
NCGC00091621-01
NCGC00091621-02
NCGC00258176-01
CAS-625-48-9
SMR001224491
SY008757
2-Nitroethanol, purum, >=95.0% (GC)
DB-054194
N0368
NS00035065
EN300-23939
Q22668732