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(2-nitrophenyl)methanol

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Identification
Molecular formula
C7H7NO3
CAS number
612-25-3
IUPAC name
(2-nitrophenyl)methanol
State
State

(2-nitrophenyl)methanol is typically in a solid state at room temperature.

Melting point (Celsius)
59.00
Melting point (Kelvin)
332.15
Boiling point (Celsius)
295.20
Boiling point (Kelvin)
568.35
General information
Molecular weight
153.14g/mol
Molar mass
153.1390g/mol
Density
1.3940g/cm3
Appearence

(2-nitrophenyl)methanol appears as a yellow solid. It is typically found in its crystalline form.

Comment on solubility

Solubility of (2-nitrophenyl)methanol

(2-nitrophenyl)methanol, with its molecular structure featuring a nitrophenyl group, exhibits notable solubility characteristics in various solvents. Here are some key points to consider:

  • Polar Solvents: This compound is expected to be soluble in polar solvents such as water and methanol due to the presence of the hydroxyl (-OH) group which can engage in hydrogen bonding.
  • Non-Polar Solvents: In contrast, its solubility in non-polar solvents like hexane or benzene may be considerably lower, primarily due to the inability of these solvents to effectively interact with the polar functional groups.
  • Solvent Proficiency: Solubility can be influenced by several factors, including temperature and pH. For instance, elevated temperatures can increase the solubility of (2-nitrophenyl)methanol in water.

In summary, while (2-nitrophenyl)methanol shows a propensity to dissolve in polar environments, it is essential to tailor solvent selection based on the desired application and conditions. The intricate balance of polarity is a crucial consideration in understanding its solubility profile.

Interesting facts

Interesting Facts about (2-Nitrophenyl)methanol

(2-Nitrophenyl)methanol, also known as 2-nitrophenylcarbinol, is a fascinating organic compound that finds its significance in various fields of chemistry and industry. Here are some intriguing aspects about this compound:

  • Structure and Functionality: The compound features a nitro group (-NO2) attached to a phenolic ring, which greatly influences its reactivity and properties. The presence of the nitro group makes it an excellent candidate for further chemical transformations.
  • Importance in Synthesis: (2-Nitrophenyl)methanol serves as a key intermediate in the synthesis of numerous pharmaceuticals and agrochemicals. It plays a pivotal role in the development of compounds that may exhibit biological activity.
  • Potential Applications: Research has indicated potential applications in fields such as medicinal chemistry and material science. It may be involved in drug design processes wherein selective modifications of chemical structures are necessary.
  • Reaction Pathways: The compound can undergo a variety of chemical reactions, including reduction, oxidation, and nucleophilic substitution. This versatility makes it a valuable target for laboratory studies and industrial applications.
  • Toxicological Studies: Like many nitro compounds, (2-nitrophenyl)methanol warrants careful handling due to potential toxicity. Research into its biological effects can provide insights into environmental safety and toxicity assessments.

In summary, (2-nitrophenyl)methanol is more than just a simple aromatic compound; its unique chemical properties and potential applications make it a subject of interest for chemists exploring innovative solutions in materials and pharmaceuticals. As one scientist aptly put it, “The beauty of organic chemistry lies in the complexity and the potential for transformation within each molecule.”

Synonyms
2-Nitrobenzyl alcohol
612-25-9
(2-Nitrophenyl)methanol
O-NITROBENZYL ALCOHOL
Benzenemethanol, 2-nitro-
2-Nitrobenzenemethanol
Benzyl alcohol, o-nitro-
o-Hydroxymethylnitrobenzene
CCRIS 7967
EINECS 210-302-6
NSC 66512
BRN 2046649
AI3-16131
NSC-66512
5M66390M78
NITROBENZYL ALCOHOL, 2-
DTXSID40210101
4-06-00-02608 (Beilstein Handbook Reference)
O-(HYDROXYMETHYL)NITROBENZENE
oNitrobenzyl alcohol
2Nitrobenzenemethanol
Benzyl alcohol, onitro
Benzenemethanol, 2nitro
oHydroxymethylnitrobenzene
Benzenemethanol, 2nitro (9CI)
Benzenemethanol, 2-nitro-(9CI)
DTXCID00132592
210-302-6
inchi=1/c7h7no3/c9-5-6-3-1-2-4-7(6)8(10)11/h1-4,9h,5h
Benzenemethanol, nitro-
2-nitrobenzylalcohol
MFCD00007186
CHEMBL369485
UNII-5M66390M78
o-nitrophenylcarbinol
o-nitro benzylalcohol
2-nitro-benzylalcohol
2-Nitrophenyl methanol
(2-Nitrophenyl)methanol #
NCIOpen2_000032
SCHEMBL68381
2-Nitrobenzyl alcohol, 97%
NSC66512
BDBM50079637
AKOS007930543
CS-W016285
FN14776
HY-W015569
PS-5308
DB-013419
N0179
NS00034611
o-Nitrobenzyl alcohol;(2-nitrophenyl)methanol
D71184
EN300-1265906
Q27262550
F0001-1612