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2-Nitropyridine

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Identification
Molecular formula
C5H4N2O2
CAS number
580-16-5
IUPAC name
2-nitropyridine
State
State

2-Nitropyridine is typically in a solid state at room temperature.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.15
Boiling point (Celsius)
251.00
Boiling point (Kelvin)
524.15
General information
Molecular weight
124.11g/mol
Molar mass
124.1110g/mol
Density
1.3165g/cm3
Appearence

2-Nitropyridine appears as a pale yellow crystalline solid. It is often available in powder form, and it may emit a mild aromatic odor. The compound is known for its bright, light-stable coloration.

Comment on solubility

Solubility of 2-Nitropyridine

2-nitropyridine, with the chemical formula C5H4N2O2, exhibits interesting solubility characteristics that are important to consider when utilizing the compound in chemical processes.

Key Aspects of Solubility

The solubility of 2-nitropyridine can be summarized as follows:

  • Polar Solvents: 2-nitropyridine is known to be soluble in polar solvents such as water and alcohols. The presence of the nitro group contributes to its polar nature.
  • Solvent Interactions: Its ability to interact favorably with polar solvents allows it to dissolve due to hydrogen bonding and dipole-dipole interactions.
  • Temperature Dependency: Generally, increased temperatures can enhance the solubility of 2-nitropyridine, facilitating its use in various reactions.
  • Limitations: However, in non-polar solvents, 2-nitropyridine shows low solubility, making its extraction or use in such mediums less efficient.

In conclusion, understanding the solubility dynamics of 2-nitropyridine is crucial for its application in synthesis and reactions, allowing chemists to select appropriate solvents effectively. As the saying goes, "the choice of solvent makes the world of difference," particularly in the realm of chemical compounds.

Interesting facts

Exploring 2-Nitropyridine

2-Nitropyridine is a fascinating compound that belongs to the class of nitropyridines, which are notable for their aromatic and basic properties. This compound has piqued the interest of chemists due to its versatile applications in various fields. Here are some intriguing aspects of 2-nitropyridine:

  • Chemical Reactivity: The presence of the nitro group (–NO2) at the second position of the pyridine ring makes it an excellent electrophile, opening up numerous pathways for chemical transformations.
  • Pharmaceutical Potential: 2-Nitropyridine is often used as a key intermediate in the synthesis of various pharmaceutical agents, primarily due to its ability to form diverse biologically active compounds.
  • Polymer Science: This compound is also involved in the preparation of certain polymers and materials that exhibit enhanced properties like conductivity and durability.
  • Research Significance: Scientists have been exploring its role in the development of organic electronic devices, such as organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs).

Research studies have shown that 2-nitropyridine can serve as a ligand in various coordination complexes, which can further exhibit unique catalytic behavior. Its ability to participate in hydrogen bonding and π-π interactions enhances its utility in supramolecular chemistry.

As stated by renowned chemists, “The interplay of reactivity and selectivity in compounds like 2-nitropyridine is what makes organic chemistry so exciting.” This highlights the compound's significance as it provides a platform for developing innovative chemical processes and exploring new materials.

Overall, 2-nitropyridine is more than just a chemical; it represents a cornerstone for advancements in materials science and medicinal chemistry, showcasing the dynamic nature of organic compounds and their transformations.

Synonyms
2-NITROPYRIDINE
15009-91-3
Pyridine, nitro-
Nitropyridine
DTXSID00878766
56778-64-4
DTXCID60993626
685-968-8
InChI=1/C5H4N2O2/c8-7(9)5-3-1-2-4-6-5/h1-4
Pyridine, 2-nitro-
Pyridine, 2-nitro- (6CI, 7CI, 8CI, 9CI)
MFCD00160414
2-nitro-pyridine
nitro-pyridine
NSC159025
NSC 159025
2-Nitropyridine, 97%
SCHEMBL33930
SCHEMBL258797
SCHEMBL448184
SCHEMBL448923
SCHEMBL449344
CHEMBL3274304
SCHEMBL29542640
NSC129217
SBB085545
AKOS000431569
NSC-129217
NSC-159025
SB53797
AS-75694
FN176777
SY358363
DB-028920
E85413
EN300-7547430
AE-842/30373015
Z361899950