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Oxymetazoline

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Identification
Molecular formula
C16H24N2O
CAS number
1491-59-4
IUPAC name
2-(o-tolylmethyl)-4,5-dihydro-1H-imidazole
State
State

At room temperature, Oxymetazoline exists as a solid. It is often used in pharmaceuticals in its hydrochloride salt form, which is easily soluble in water and used in nasal sprays and other decongestant applications.

Melting point (Celsius)
234.00
Melting point (Kelvin)
507.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
260.35g/mol
Molar mass
260.3470g/mol
Density
1.0662g/cm3
Appearence

Oxymetazoline typically appears as a colorless to light yellow solid. It can appear in various crystalline forms depending on the specific formulation and any additives or solvents present.

Comment on solubility

Solubility of 2-(o-tolylmethyl)-4,5-dihydro-1H-imidazole

The solubility of 2-(o-tolylmethyl)-4,5-dihydro-1H-imidazole is an intriguing aspect of its chemical behavior. This compound, due to its structural characteristics, exhibits distinct solubility traits in various solvents.

Solubility Characteristics

  • Solvent Dependency: The solubility can greatly vary depending on the solvent used. It is generally expected to show higher solubility in organic solvents such as ethanol and methanol compared to water.
  • Hydrophobic Nature: Given the presence of aromatic groups (o-tolyl), the compound tends to be more hydrophobic, which usually leads to lower solubility in polar solvents.
  • Temperature Influence: As with many organic compounds, increasing the temperature may enhance solubility, making it beneficial for experimental procedures.

In conclusion, understanding the solubility of 2-(o-tolylmethyl)-4,5-dihydro-1H-imidazole is essential for its application in chemical synthesis and formulation. Exploring varied solvent environments can result in better utilization of its properties, making solubility a critical factor in its chemistry.

Interesting facts

Interesting Facts about 2-(o-tolylmethyl)-4,5-dihydro-1H-imidazole

2-(o-tolylmethyl)-4,5-dihydro-1H-imidazole is a fascinating compound that belongs to the family of imidazoles, which are known for their diverse applications in medicine and material science. Here are some key points that make this compound particularly notable:

  • Pharmacological Significance: Imidazole derivatives often exhibit a wide range of biological properties, making them valuable in pharmaceuticals. They can act as antifungal, antibacterial, and antiviral agents.
  • Chemical Structure: The unique structure of this compound includes an o-tolylmethyl group, which contributes to its distinct chemical reactivity and potential interactions with biological targets.
  • Potential Uses: Research is ongoing to explore the role of 2-(o-tolylmethyl)-4,5-dihydro-1H-imidazole in catalysis, especially in tandem reactions that may lead to the development of new synthetic pathways.
  • Coordination Chemistry: Compounds containing an imidazole ring are known to form stable complexes with metal ions, which can be utilized in creating new materials, sensors, and catalysts.

As one delves deeper into the world of imidazole compounds, the complexity and importance of compounds like 2-(o-tolylmethyl)-4,5-dihydro-1H-imidazole become increasingly clear. Its interactions and contributions to chemistry are a testament to the versatility of imidazole derivatives. "Understanding these compounds is crucial for innovating new therapeutic strategies and materials."

This compound exemplifies the intricate balance between structure and function in chemical entities, inviting further exploration and study in the field of organic chemistry and medicinal research.

Synonyms
2-IMIDAZOLINE, 2-(o-METHYLBENZYL)-
2-(o-Methylbenzyl)-2-imidazoline
3038-50-4
BRN 0957386
DTXSID70184462
DTXCID80106953
5-23-07-00012 (beilstein handbook reference)
SCHEMBL953620