Skip to main content

2-Oxaspiro[4.5]decan-3-one

ADVERTISEMENT
Identification
Molecular formula
C9H14O2
CAS number
15892-23-6
IUPAC name
2-oxaspiro[4.5]decan-3-one
State
State

At room temperature, 2-oxaspiro[4.5]decan-3-one is generally found as a liquid. Its stability and unique structure make it a notable compound for various chemical applications.

Melting point (Celsius)
29.00
Melting point (Kelvin)
302.15
Boiling point (Celsius)
238.00
Boiling point (Kelvin)
511.15
General information
Molecular weight
154.21g/mol
Molar mass
154.2060g/mol
Density
1.1441g/cm3
Appearence

2-Oxaspiro[4.5]decan-3-one appears as a colorless to pale yellow liquid. It is typically used in organic synthesis and might also be found as an intermediate in various chemical processes. The compound has a distinctive spiro structure, contributing to its unique properties.

Comment on solubility

Solubility of 2-oxaspiro[4.5]decan-3-one

When investigating the solubility characteristics of 2-oxaspiro[4.5]decan-3-one, several factors come into play, particularly its molecular structure and polarity. This compound, being a spirocyclic ketone with an ether functional group, exhibits unique solubility behavior:

  • Polarity: The presence of the carbonyl group (C=O) generally increases the compound's polarity, suggesting a potential for solubility in polar solvents such as water.
  • Solvent Compatibility: 2-oxaspiro[4.5]decan-3-one may show affinity towards organic solvents including ethanol, methanol, and acetone due to its spirocyclic nature, which can enhance interaction with these solvents.
  • Hydrophilic and Hydrophobic Balance: The balance of hydrophilic groups (like the carbonyl) and hydrophobic regions (the spirocarbon framework) greatly influences the solubility profile.

Overall, while specific solubility data may not be readily available, one can anticipate that 2-oxaspiro[4.5]decan-3-one demonstrates moderate solubility in polar solvents, making it more soluble in organic solvents rather than in water due to its complex structural features.

As a final note, the solubility of such compounds often requires empirical data to validate these expectations and to provide a more comprehensive understanding.

Interesting facts

Interesting Facts about 2-Oxaspiro[4.5]decan-3-one

2-Oxaspiro[4.5]decan-3-one is a fascinating compound that showcases the complexity and creativity found in organic chemistry. Here are some intriguing aspects about this unique molecule:

  • Structural Uniqueness: The term "spiro" refers to a molecular structure in which two or more rings are connected at a single atom. In this case, 2-oxaspiro[4.5]decan-3-one features a spiro arrangement, highlighting the interesting spatial dynamics that can arise in organic compounds.
  • Applications in Synthesis: Compounds like 2-oxaspiro[4.5]decan-3-one serve as valuable intermediates in organic synthesis. Their unique structure allows them to participate in various chemical reactions, making them potential building blocks for more complex molecules.
  • Pharmaceutical Relevance: The presence of a ketone functional group, coupled with its spiro framework, positions this compound as a potential candidate in drug design. Many bioactive molecules incorporate similar motifs, thus warranting further exploration for medicinal applications.
  • Chirality: Some spiro compounds are chiral, meaning they can exist in two non-superimposable mirror forms. This chirality can influence the biological activity of molecules, making such compounds particularly interesting for studies in stereochemistry.
  • Research Insights: Ongoing research into spiro compounds, including 2-oxaspiro[4.5]decan-3-one, could unveil new synthetic methodologies and reveal insights into reaction mechanisms, especially in cycloaddition reactions and rearrangements.

In conclusion, 2-oxaspiro[4.5]decan-3-one exemplifies the beauty of molecular architecture and functional diversity found in organic chemistry. Its significant role in various applications makes it a topic worth delving into for both budding chemists and seasoned researchers!

Synonyms
2-Oxaspiro[4.5]decan-3-one
7236-78-4
2-OXASPIRO(4.5)DECAN-3-ONE
GO 177
8TP5X2BOF8
NSC 169568
BRN 0119521
beta,beta-Pentamethylene-alpha-butyrolactone
UNII-8TP5X2BOF8
NSC-169568
Cyclohexaneacetic acid, 1-(hydroxymethyl)-, gamma-lactone
DTXSID10222675
5-17-09-00205 (Beilstein Handbook Reference)
Cyclohexaneacetic acid, 1-(hydroxymethyl)-, .gamma.-lactone
DTXCID40145166
BUTANOIC ACID,4-HYDROXY,3,3-PENTAMETHYLENE,LACTONE BUTYROLACTONE,BETA,BETA-PENTAMETHYLENE
inchi=1/c9h14o2/c10-8-6-9(7-11-8)4-2-1-3-5-9/h1-7h
Godecke
3-oxaspiro[4.5]decan-2-one
SCHEMBL13076899
HAA23678
NSC169568
WLN: T5OV DXTJ D-& AL6XTJ
DB-261378
EN300-160391
.beta.,.beta.-Pentamethylene-.alpha.-butyrolactone
BUTANOIC ACID,4-HYDROXY,3,3-PENTAMETHYLENE,LACTONE BUTYROLACTONE,BETA,BETA-PENTAMETHYLENE