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Diphenhydramine Hydrochloride

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Identification
Molecular formula
C17H22ClNO
CAS number
147-24-0
IUPAC name
(2-oxo-1,2-diphenyl-ethyl)ammonium;chloride
State
State

At room temperature, diphenhydramine hydrochloride exists as a solid. It is often utilized in its powdered form for pharmaceutical applications, especially in the formulation of tablets and capsules.

Melting point (Celsius)
168.00
Melting point (Kelvin)
441.00
Boiling point (Celsius)
340.00
Boiling point (Kelvin)
613.00
General information
Molecular weight
291.82g/mol
Molar mass
291.8240g/mol
Density
1.0840g/cm3
Appearence

Diphenhydramine hydrochloride appears as a white, crystalline powder. It is known for being highly soluble in water and slightly soluble in alcohol. As a solid, it is stable under normal circumstances, but it should be protected from light and moisture.

Comment on solubility

Solubility of (2-oxo-1,2-diphenyl-ethyl)ammonium chloride

The solubility of (2-oxo-1,2-diphenyl-ethyl)ammonium chloride exhibits interesting characteristics, influenced by its ionic and molecular structure. This compound, often categorized as a quaternary ammonium salt, can generally be soluble in polar solvents.

Key points regarding its solubility include:

  • Polar Solvents: The presence of the ammonium chloride moiety enhances the solubility in water and other polar solvents.
  • Solvent Interaction: The ionic nature of the chloride ion interacts favorably with polar solvents, promoting dissolution.
  • Temperature Dependence: As is common with many salts, temperature can significantly affect solubility; increasing temperature usually results in higher solubility.

However, it is important to note that solubility might vary based on specific conditions, such as the presence of other ions or solutes in the solution. As a general trend, quaternary ammonium salts like this compound tend to be more soluble in organic solvents compared to their primary counterparts, which can enhance their utility in various chemical applications.

In summary, (2-oxo-1,2-diphenyl-ethyl)ammonium chloride’s solubility profile underscores its potential for use in diverse chemical ecosystems where ionic interactions play a critical role.

Interesting facts

Interesting Facts about (2-oxo-1,2-diphenyl-ethyl)ammonium Chloride

(2-oxo-1,2-diphenyl-ethyl)ammonium chloride is a fascinating compound that falls within the realm of organic chemistry. Its unique structure allows for various implications in both scientific research and practical applications.

Key Characteristics

  • Potential Biological Activity: Compounds containing the ammonium group often exhibit interesting biological properties. They may show potential in medicinal chemistry due to their ability to interact with biological targets.
  • Versatile Synthesis: The synthesis of this compound can often involve a variety of synthetic methodologies. Researchers may utilize creative routes to obtain this compound, including reactions that modify aromatic rings and introduce the carbonyl functionality.
  • Chloride Ion Role: The chloride ion in this compound enhances its solubility in certain solvents, which may influence how it interacts with other compounds in chemical reactions and applications.

Applications and Research

Research into compounds like (2-oxo-1,2-diphenyl-ethyl)ammonium chloride can lead to the discovery of new materials and pharmaceuticals. Scientists can explore:

  • Medicinal Uses: The structure resembles known pharmacophores, making it a candidate for investigation in drug development.
  • Supramolecular Chemistry: Its ability to form complexes with other compounds may allow it to be studied in supramolecular assemblies.
  • Catalysis: Researchers are intrigued by the potential of this compound to act as a catalyst in various organic reactions.

As noted by many chemists, “The creativity in chemistry often lies in the unexpected potential for ordinary compounds to serve extraordinary purposes.” Exploring (2-oxo-1,2-diphenyl-ethyl)ammonium chloride opens doors to various intriguing possibilities in the field of chemistry.

Synonyms
Desylamine hydrochloride
2-Amino-1,2-diphenylethanone hydrochloride
Desylammonium chloride
NSC 33420
2-Amino-2-phenylacetophenone hydrochloride
Ethanone, 2-amino-1,2-diphenyl-, hydrochloride